| # | Title | Journal | Year | Citations |
|---|
| 1 | Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification | Gut | 1999 | 1,959 |
| 2 | A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer | New England Journal of Medicine | 2015 | 1,084 |
| 3 | Risk of recurrence of gastrointestinal stromal tumour after surgery: an analysis of pooled population-based cohorts | Lancet Oncology, The | 2012 | 790 |
| 4 | Complications to thyroid surgery: results as reported in a database from a multicenter audit comprising 3,660 patients | Langenbeck's Archives of Surgery | 2008 | 576 |
| 5 | Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients | British Journal of Surgery | 2009 | 436 |
| 6 | MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool | Nature | 2014 | 419 |
| 7 | Helicobacter pylori in gastric cancer established by CagA immunoblot as a marker of past infection | Gastroenterology | 2001 | 379 |
| 8 | EURECCA colorectal: Multidisciplinary management: European consensus conference colon & rectum | European Journal of Cancer | 2014 | 349 |
| 9 | Continued (5-Year) Followup of A Randomized Clinical Study Comparing Antireflux Surgery and Omeprazole in Gastroesophageal Reflux Disease | Journal of the American College of Surgeons | 2001 | 348 |
| 10 | Urinary Incontinence and Erectile Dysfunction After Robotic Versus Open Radical Prostatectomy: A Prospective, Controlled, Nonrandomised Trial | European Urology | 2015 | 347 |
| 11 | Laparoscopy for abdominal emergencies | Surgical Endoscopy and Other Interventional Techniques | 2006 | 346 |
| 12 | Blood Biomarkers for Brain Injury in Concussed Professional Ice Hockey Players | JAMA Neurology | 2014 | 336 |
| 13 | The transfer of basic skills learned in a laparoscopic simulator to the operating room | Surgical Endoscopy and Other Interventional Techniques | 2002 | 281 |
| 14 | The Effect of Postoperative Intravenous Feeding (TPN) on Outcome Following Major Surgery Evaluated in a Randomized Study | Annals of Surgery | 1993 | 274 |
| 15 | Carbohydrate-dependent inhibition of Helicobacter pylori colonization using porcine milk | Glycobiology | 2006 | 264 |
| 16 | Survival benefit in a randomized clinical trial of faecal occult blood screening for colorectal cancer | British Journal of Surgery | 2008 | 264 |
| 17 | Body composition and time course changes in regional distribution of fat and lean tissue in unselected cancer patients on palliative care—Correlations with food intake, metabolism, exercise capacity, and hormones | Cancer | 2005 | 257 |
| 18 | Results of Screening, Rescreening, and Follow-up in a Prospective Randomized Study for Detection of Colorectal Cancer by Fecal Occult Blood Testing: Results for 68,308 Subjects | Scandinavian Journal of Gastroenterology | 1994 | 251 |
| 19 | Screening and rescreening for colorectal cancer. A controlled trial of fecal occult blood testing in 27,700 subjects | Cancer | 1988 | 250 |
| 20 | Laparoscopic resection of colon Cancer: Consensus of the European Association of Endoscopic Surgery (EAES) | Surgical Endoscopy and Other Interventional Techniques | 2004 | 231 |
| 21 | Improved Survival of Patients with Papillary Thyroid Cancer after Surgical Microdissection | World Journal of Surgery | 1996 | 230 |
| 22 | Management of acute cholecystitis in the laparoscopic era: Results of a prospective, randomized clinical trial | Journal of Gastrointestinal Surgery | 2003 | 216 |
| 23 | Increased risk of death from primary hyperparathyroidism — an update | European Journal of Clinical Investigation | 1998 | 204 |
| 24 | Engineering microporosity in bacterial cellulose scaffolds | Journal of Tissue Engineering and Regenerative Medicine | 2008 | 204 |
| 25 | Randomized clinical trial of the effect of interferon α on survival in patients with disseminated midgut carcinoid tumours | British Journal of Surgery | 2003 | 202 |
| 26 | Role of endogenous tumor necrosis factor alpha and interleukin 1 for experimental tumor growth and the development of cancer cachexia | Cancer Research | 1991 | 201 |
| 27 | High Expression of Complement Components in Omental Adipose Tissue in Obese Men | Obesity | 2003 | 195 |
| 28 | Palliative nutritional intervention in addition to cyclooxygenase and erythropoietin treatment for patients with malignant disease: Effects on survival, metabolism, and function | Cancer | 2004 | 194 |
| 29 | Anti-inflammatory treatment may prolong survival in undernourished patients with metastatic solid tumors | Cancer Research | 1994 | 190 |
| 30 | Randomized clinical trial of open versus laparoscopic cholecystectomy in the treatment of acute cholecystitis | British Journal of Surgery | 2004 | 189 |
| 31 | Laparoscopic Lavage Is Feasible and Safe for the Treatment of Perforated Diverticulitis With Purulent Peritonitis | Annals of Surgery | 2016 | 189 |
| 32 | Toward a Consensus on Centralization in Surgery | Annals of Surgery | 2018 | 187 |
| 33 | Laparoscopic Gastric Bypass: Development of Technique, Respiratory Function, and Long-Term Outcome | Obesity Surgery | 2003 | 184 |
| 34 | Influence of cultivation conditions on mechanical and morphological properties of bacterial cellulose tubes | Biotechnology and Bioengineering | 2007 | 181 |
| 35 | Five-Year Outcomes After Laparoscopic Gastric Bypass and Laparoscopic Duodenal Switch in Patients With Body Mass Index of 50 to 60 | JAMA Surgery | 2015 | 177 |
| 36 | Fertility after ileal pouch–anal anastomosis in women with ulcerative colitis | British Journal of Surgery | 2002 | 170 |
| 37 | Randomized clinical trial of the costs of open and laparoscopic surgery for colonic cancer | British Journal of Surgery | 2004 | 166 |
| 38 | Diagnosis, treatment, and consequences of anastomotic leakage in colorectal surgery | International Journal of Colorectal Disease | 2017 | 165 |
| 39 | Current Response and Management Decisions of the European Union to the COVID-19 Outbreak: A Review | Sustainability | 2020 | 160 |
| 40 | Continuous Intravenous Infusion of Omeprazole in Elderly Patients with Peptic Ulcer Bleeding Results of a Placebo-Controlled Multicenter Study | Scandinavian Journal of Gastroenterology | 1997 | 156 |
| 41 | Future cancer research priorities in the USA: a Lancet Oncology Commission | Lancet Oncology, The | 2017 | 153 |
| 42 | Transplantation of an allogeneic vein bioengineered with autologous stem cells: a proof-of-concept study | Lancet, The | 2012 | 151 |
| 43 | Breast conservation surgery, with and without radiotherapy, in women with lymph node-negative breast cancer: a randomised clinical trial in a population with access to public mammography screening | European Journal of Cancer | 2003 | 148 |
| 44 | Pneumatic Dilatation or Laparoscopic Cardiomyotomy in the Management of Newly Diagnosed Idiopathic Achalasia | World Journal of Surgery | 2007 | 145 |
| 45 | Neoadjuvant, adjuvant and palliative treatment of gastrointestinal stromal tumours (GIST) with imatinib: a centre-based study of 17 patients | British Journal of Cancer | 2003 | 144 |
| 46 | Randomized clinical trial of laparoscopic gastric bypass versus laparoscopic duodenal switch for superobesity | British Journal of Surgery | 2010 | 141 |
| 47 | Effect of KIT and PDGFRA Mutations on Survival in Patients With Gastrointestinal Stromal Tumors Treated With Adjuvant Imatinib | JAMA Oncology | 2017 | 141 |
| 48 | The Role of Cytokines, Coagulation, and Fibrinolysis in Peritoneal Tissue Repair | The European Journal of Surgery | 1999 | 140 |
| 49 | Comparison of Outcomes Twelve Years After Antireflux Surgery or Omeprazole Maintenance Therapy for Reflux Esophagitis | Clinical Gastroenterology and Hepatology | 2009 | 140 |
| 50 | Orthotopic liver or multivisceral transplantation as treatment of metastatic neuroendocrine tumors | Liver Transplantation | 2007 | 139 |
