| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 2 | Standardization of sample collection, isolation and analysis methods in extracellular vesicle research | Journal of Extracellular Vesicles | 2013 | 1,837 |
| 3 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 4 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 5 | Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation | PLoS Biology | 2012 | 1,064 |
| 6 | Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study | Gastroenterology | 2021 | 913 |
| 7 | European consensus conference on faecal microbiota transplantation in clinical practice | Gut | 2017 | 793 |
| 8 | Irritable bowel syndrome | Nature Reviews Disease Primers | 2016 | 674 |
| 9 | Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture | Nature | 2015 | 483 |
| 10 | Identification of an Intestinal Microbiota Signature Associated With Severity of Irritable Bowel Syndrome | Gastroenterology | 2017 | 470 |
| 11 | Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome as Well as Traditional Dietary Advice: A Randomized Controlled Trial | Gastroenterology | 2015 | 463 |
| 12 | Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology | JAMA Neurology | 2019 | 455 |
| 13 | The power of genetic diversity in genome-wide association studies of lipids | Nature | 2021 | 353 |
| 14 | The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study | PLoS Genetics | 2015 | 331 |
| 15 | Prevalence of Rome IV Functional Bowel Disorders Among Adults in the United States, Canada, and the United Kingdom | Gastroenterology | 2020 | 249 |
| 16 | New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk | Nature Communications | 2016 | 245 |
| 17 | Sex Steroid Actions in Male Bone | Endocrine Reviews | 2014 | 239 |
| 18 | Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD | Alimentary Pharmacology and Therapeutics | 2015 | 218 |
| 19 | Associations of pre-pregnancy body mass index and gestational weight gain with pregnancy outcome and postpartum weight retention: a prospective observational cohort study | BMC Pregnancy and Childbirth | 2014 | 209 |
| 20 | Metabolic effects of Lactobacillus reuteriDSM 17938 in people with type 2 diabetes: A randomized controlled trial | Diabetes, Obesity and Metabolism | 2017 | 199 |
| 21 | Epidemiology, clinical characteristics, and associations for symptom-based Rome IV functional dyspepsia in adults in the USA, Canada, and the UK: a cross-sectional population-based study | The Lancet Gastroenterology and Hepatology | 2018 | 199 |
| 22 | Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome | Nature Medicine | 2019 | 193 |
| 23 | Visceral hypersensitivity is associated with GI symptom severity in functional GI disorders: consistent findings from five different patient cohorts | Gut | 2018 | 186 |
| 24 | Multivariate modelling of faecal bacterial profiles of patients with IBS predicts responsiveness to a diet low in FODMAPs | Gut | 2018 | 176 |
| 25 | Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo‐controlled, double‐blind, clinical trial | Journal of Internal Medicine | 2018 | 169 |
| 26 | Increased colonic bile acid exposure: a relevant factor for symptoms and treatment in IBS | Gut | 2015 | 167 |
| 27 | Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults | PLoS Genetics | 2017 | 158 |
| 28 | Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels | Nature Communications | 2016 | 153 |
| 29 | An approach to the diagnosis and management of Rome IV functional disorders of chronic constipation | Expert Review of Gastroenterology and Hepatology | 2020 | 148 |
| 30 | Crosstalk at the mucosal border: importance of the gut microenvironment in IBS | Nature Reviews Gastroenterology and Hepatology | 2015 | 147 |
| 31 | The Prevalence and Impact of Overlapping Rome IV-Diagnosed Functional Gastrointestinal Disorders on Somatization, Quality of Life, and Healthcare Utilization: A Cross-Sectional General Population Study in Three Countries | American Journal of Gastroenterology | 2018 | 138 |
| 32 | Cytokine imbalance in irritable bowel syndrome: a systematic review and meta‐analysis | Neurogastroenterology and Motility | 2014 | 130 |
| 33 | Work Productivity and Activity Impairment in Irritable Bowel Syndrome (IBS): A Multifaceted Problem | American Journal of Gastroenterology | 2018 | 127 |
| 34 | Functional variants in the sucrase–isomaltase gene associate with increased risk of irritable bowel syndrome | Gut | 2018 | 120 |
| 35 | Putative Cut‐Points in Sarcopenia Components and Incident Adverse Health Outcomes: An SDOC Analysis | Journal of the American Geriatrics Society | 2020 | 120 |
| 36 | Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 118 |
| 37 | Macrophage and dendritic cell subsets in IBD: ALDH+ cells are reduced in colon tissue of patients with ulcerative colitis regardless of inflammation | Mucosal Immunology | 2016 | 115 |
| 38 | Differences in dietary intakes, food sources and determinants of total flavonoids between Mediterranean and non-Mediterranean countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study | British Journal of Nutrition | 2013 | 114 |
| 39 | Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis | American Journal of Human Genetics | 2017 | 112 |
| 40 | European society of neurogastroenterology and motility guidelines on functional constipation in adults | Neurogastroenterology and Motility | 2020 | 110 |
| 41 | Exosomes in diagnostic and therapeutic applications: biomarker, vaccine and RNA interference delivery vehicle | Expert Opinion on Biological Therapy | 2015 | 108 |
| 42 | Clinical classification of adult patients with chronic intestinal failure due to benign disease: An international multicenter cross-sectional survey | Clinical Nutrition | 2018 | 107 |
| 43 | New treatments and therapeutic targets for IBS and other functional bowel disorders | Nature Reviews Gastroenterology and Hepatology | 2018 | 99 |
| 44 | Spotlight on microRNAs in allergy and asthma | Allergy: European Journal of Allergy and Clinical Immunology | 2021 | 98 |
| 45 | EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy | Clinical and Translational Allergy | 2012 | 97 |
| 46 | Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation | Journal of Translational Medicine | 2016 | 97 |
| 47 | Epidemiology, Clinical Characteristics, and Associations for Rome IV Functional Nausea and Vomiting Disorders in Adults | Clinical Gastroenterology and Hepatology | 2019 | 93 |
| 48 | Maternal testosterone exposure increases anxiety-like behavior and impacts the limbic system in the offspring | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 91 |
| 49 | How the Change in IBS Criteria From Rome III to Rome IV Impacts on Clinical Characteristics and Key Pathophysiological Factors | American Journal of Gastroenterology | 2018 | 90 |
| 50 | Anti-inflammatory Diet In Rheumatoid Arthritis (ADIRA)—a randomized, controlled crossover trial indicating effects on disease activity | American Journal of Clinical Nutrition | 2020 | 90 |
