# | Title | Journal | Year | Citations |
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1 | Autophagy fights disease through cellular self-digestion | Nature | 2008 | 5,714 |
2 | Autophagy: Renovation of Cells and Tissues | Cell | 2011 | 4,844 |
3 | Methods in Mammalian Autophagy Research | Cell | 2010 | 3,939 |
4 | Autophagy: process and function | Genes and Development | 2007 | 3,312 |
5 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
6 | Autophagy in immunity and inflammation | Nature | 2011 | 2,901 |
7 | The Role of Atg Proteins in Autophagosome Formation | Annual Review of Cell and Developmental Biology | 2011 | 2,587 |
8 | How to Interpret LC3 Immunoblotting | Autophagy | 2007 | 2,207 |
9 | Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy | Molecular Biology of the Cell | 2009 | 1,743 |
10 | A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells | Nature | 2008 | 1,341 |
11 | Autophagy in mammalian development and differentiation | Nature Cell Biology | 2010 | 1,313 |
12 | Autophagy-deficient mice develop multiple liver tumors | Genes and Development | 2011 | 1,094 |
13 | The Hairpin-type Tail-Anchored SNARE Syntaxin 17 Targets to Autophagosomes for Fusion with Endosomes/Lysosomes | Cell | 2012 | 1,042 |
14 | Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG | Molecular Biology of the Cell | 2008 | 1,025 |
15 | The role of the Atg1/ULK1 complex in autophagy regulation | Current Opinion in Cell Biology | 2010 | 934 |
16 | Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice | Nature Cell Biology | 2009 | 889 |
17 | FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells | Journal of Cell Biology | 2008 | 833 |
18 | Protein Turnover Via Autophagy: Implications for Metabolism | Annual Review of Nutrition | 2007 | 730 |
19 | Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins | Autophagy | 2010 | 714 |
20 | LC3, an Autophagosome Marker, Can be Incorporated into Protein Aggregates Independent of Autophagy: Caution in the Interpretation of LC3 Localization | Autophagy | 2007 | 516 |
21 | Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane | Journal of Biological Chemistry | 2011 | 516 |
22 | Autophagy Is Essential for Preimplantation Development of Mouse Embryos | Science | 2008 | 485 |
23 | Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance | Nature | 2008 | 452 |
24 | In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells | Immunity | 2010 | 425 |
25 | The HOPS complex mediates autophagosome–lysosome fusion through interaction with syntaxin 17 | Molecular Biology of the Cell | 2014 | 402 |
26 | Atg101, a novel mammalian autophagy protein interacting with Atg13 | Autophagy | 2009 | 400 |
27 | De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood | Nature Genetics | 2013 | 396 |
28 | p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding | Journal of Cell Biology | 2011 | 366 |
29 | Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets | Molecular Biology of the Cell | 2012 | 339 |
30 | The structure of Atg4B–LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy | EMBO Journal | 2009 | 329 |
31 | Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids | Autophagy | 2014 | 323 |
32 | Constitutive Activation of Chaperone-mediated Autophagy in Cells with Impaired Macroautophagy | Molecular Biology of the Cell | 2008 | 281 |
33 | MiR‐133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures | EMBO Journal | 2014 | 272 |
34 | A comprehensive glossary of autophagy-related molecules and processes (2ndedition) | Autophagy | 2011 | 255 |
35 | Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy | Journal of Cell Science | 2012 | 237 |
36 | Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury | Autophagy | 2012 | 228 |
37 | DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death | Cell Death and Differentiation | 2008 | 222 |
38 | Tti1 and Tel2 Are Critical Factors in Mammalian Target of Rapamycin Complex Assembly | Journal of Biological Chemistry | 2010 | 215 |
39 | Physiological Functions of Autophagy | Current Topics in Microbiology and Immunology | 2009 | 209 |
40 | Mitofusin 2 Inhibits Mitochondrial Antiviral Signaling | Science Signaling | 2009 | 206 |
41 | Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells | Molecular and Cellular Biology | 2011 | 201 |
42 | Dynamic association of the ULK1 complex with omegasomes during autophagy induction | Journal of Cell Science | 2013 | 197 |
43 | Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site | Autophagy | 2013 | 196 |
44 | Physiological role of autophagy as an intracellular recycling system: With an emphasis on nutrient metabolism | Seminars in Cell and Developmental Biology | 2010 | 193 |
45 | Ultrastructural analysis of autophagosome organization using mammalian autophagy-deficient cells | Journal of Cell Science | 2014 | 184 |
46 | Dynamics of Mitochondrial DNA Nucleoids Regulated by Mitochondrial Fission Is Essential for Maintenance of Homogeneously Active Mitochondria during Neonatal Heart Development | Molecular and Cellular Biology | 2015 | 165 |
47 | FIP200 regulates targeting of Atg16L1 to the isolation membrane | EMBO Reports | 2013 | 159 |
48 | Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection | Journal of Cell Biology | 2010 | 156 |
49 | Autophagy in Protein and Organelle Turnover | Cold Spring Harbor Symposia on Quantitative Biology | 2011 | 146 |
50 | Chapter 2 Methods for Monitoring Autophagy Using GFP‐LC3 Transgenic Mice | Methods in Enzymology | 2009 | 142 |