# | Title | Journal | Year | Citations |
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1 | Autoamplification of NFATc1 expression determines its essential role in bone homeostasis | Journal of Experimental Medicine | 2005 | 758 |
2 | Osteoclast‐specific Dicer gene deficiency suppresses osteoclastic bone resorption | Journal of Cellular Biochemistry | 2010 | 148 |
3 | Inhibition of Fractalkine Ameliorates Murine Collagen-Induced Arthritis | Journal of Immunology | 2004 | 136 |
4 | Pathogenic role of the CXCL16-CXCR6 pathway in rheumatoid arthritis | Arthritis and Rheumatism | 2005 | 136 |
5 | Update on the Japanese guidelines for the use of infliximab and etanercept in rheumatoid arthritis | Modern Rheumatology | 2007 | 130 |
6 | Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts | Arthritis Research and Therapy | 2006 | 126 |
7 | Polymyositis/dermatomyositis and interstitial lung disease: A new therapeutic approach with T-cell-specific immunosuppressants | Autoimmunity | 2005 | 120 |
8 | miR-31 controls osteoclast formation and bone resorption by targeting RhoA | Arthritis Research and Therapy | 2013 | 117 |
9 | Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor | Arthritis Research and Therapy | 2009 | 112 |
10 | A multicenter phase I/II trial of rituximab for refractory systemic lupus erythematosus | Modern Rheumatology | 2007 | 107 |
11 | Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) study | Modern Rheumatology | 2014 | 105 |
12 | The Multicenter Study of a New Assay for Simultaneous Detection of Multiple Anti-Aminoacyl-tRNA Synthetases in Myositis and Interstitial Pneumonia | PLoS ONE | 2014 | 104 |
13 | SomaticNLRP3mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by different phenotypes of cryopyrin-associated periodic syndromes | Annals of the Rheumatic Diseases | 2015 | 104 |
14 | Transient receptor potential vanilloid 4 deficiency suppresses unloading‐induced bone loss | Journal of Cellular Physiology | 2008 | 103 |
15 | Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis | Arthritis Research and Therapy | 2011 | 95 |
16 | A multicenter phase I/II trial of rituximab for refractory systemic lupus erythematosus | Modern Rheumatology | 2007 | 92 |
17 | Disease-Association Analysis of an Inflammation-Related Feedback Loop | Cell Reports | 2013 | 90 |
18 | Update on the Japanese guidelines for the use of infliximab and etanercept in rheumatoid arthritis | Modern Rheumatology | 2007 | 86 |
19 | Therapeutic effects of interleukin‐6 blockade in a murine model of polymyositis that does not require interleukin‐17A | Arthritis and Rheumatism | 2009 | 83 |
20 | Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis | Modern Rheumatology | 2009 | 75 |
21 | Cannabinoid receptor 2 as a potential therapeutic target in rheumatoid arthritis | BMC Musculoskeletal Disorders | 2014 | 72 |
22 | Effects of intravenous immunoglobulin therapy in Japanese patients with polymyositis and dermatomyositis resistant to corticosteroids: a randomized double-blind placebo-controlled trial | Modern Rheumatology | 2012 | 71 |
23 | Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis | Arthritis and Rheumatism | 2009 | 66 |
24 | Official Japanese guidelines for the use of infliximab for rheumatoid arthritis | Modern Rheumatology | 2005 | 63 |
25 | A new murine model to define the critical pathologic and therapeutic mediators of polymyositis | Arthritis and Rheumatism | 2007 | 62 |
26 | Temporal Expression of Growth Factors Triggered by Epiregulin Regulates Inflammation Development | Journal of Immunology | 2015 | 62 |
27 | Prediction of and prophylaxis againstPneumocystispneumonia in patients with connective tissue diseases undergoing medium- or high-dose corticosteroid therapy | Modern Rheumatology | 2005 | 61 |
28 | Guidelines for the proper use of etanercept in Japan | Modern Rheumatology | 2006 | 58 |
29 | CXCR7 agonists inhibit the function of CXCL12 by down-regulation of CXCR4 | Biochemical and Biophysical Research Communications | 2013 | 58 |
30 | Golimumab monotherapy in Japanese patients with active rheumatoid arthritis despite prior treatment with disease-modifying antirheumatic drugs: results of the phase 2/3, multicentre, randomised, double-blind, placebo-controlled GO-MONO study through 24 weeks | Annals of the Rheumatic Diseases | 2013 | 51 |
31 | Suppression of elevations in serum C reactive protein levels by anti-IL-6 autoantibodies in two patients with severe bacterial infections | Annals of the Rheumatic Diseases | 2013 | 50 |
32 | p16INK4a Exerts an Anti-Inflammatory Effect through Accelerated IRAK1 Degradation in Macrophages | Journal of Immunology | 2012 | 49 |
33 | Efficacy and safety of certolizumab pegol plus methotrexate in Japanese rheumatoid arthritis patients with an inadequate response to methotrexate: the J-RAPID randomized, placebo-controlled trial | Modern Rheumatology | 2014 | 49 |
34 | Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis | Modern Rheumatology | 2009 | 48 |
35 | Favorable outcomes with tacrolimus in two patients with refractory interstitial lung disease associated with polymyositis/dermatomyositis | Clinical and Experimental Rheumatology | 2005 | 47 |
36 | Pneumocystis jiroveciipneumonia associated with etanercept treatment in patients with rheumatoid arthritis: a retrospective review of 15 cases and analysis of risk factors | Modern Rheumatology | 2012 | 46 |
37 | Arthritic Joint-Targeting Small Interfering RNA-Encapsulated Liposome: Implication for Treatment Strategy for Rheumatoid Arthritis | Journal of Pharmacology and Experimental Therapeutics | 2012 | 45 |
38 | Epidemiological characteristics of rheumatoid arthritis in Japan: Prevalence estimates using a nationwide population-based questionnaire survey | Modern Rheumatology | 2020 | 45 |
39 | Step-up versus primary intensive approach to the treatment of interstitial pneumonia associated with dermatomyositis/polymyositis: a retrospective study | Modern Rheumatology | 2007 | 43 |
40 | Structural and functional outcomes of a therapeutic strategy targeting low disease activity in patients with elderly-onset rheumatoid arthritis: a prospective cohort study (CRANE) | Rheumatology | 2015 | 42 |
41 | Efficacy and safety of certolizumab pegol without methotrexate co-administration in Japanese patients with active rheumatoid arthritis: The HIKARI randomized, placebo-controlled trial | Modern Rheumatology | 2014 | 40 |
42 | Efficacy and safety of rituximab in Japanese patients with systemic lupus erythematosus and lupus nephritis who are refractory to conventional therapy | Modern Rheumatology | 2016 | 40 |
43 | Therapeutic effect of D1-like dopamine receptor antagonist on collagen-induced arthritis of mice | Modern Rheumatology | 2011 | 37 |
44 | Pneumatosis Cystoides Intestinalis Following Lupus Enteritis and Peritonitis | Internal Medicine | 2008 | 33 |
45 | Prevalence and incidence of polymyositis and dermatomyositis in Japan | Modern Rheumatology | 2014 | 31 |
46 | Guidelines for the proper use of etanercept in Japan | Modern Rheumatology | 2006 | 31 |
47 | Leflunomide-related acute interstitial pneumonia in two patients with rheumatoid arthritis: autopsy findings with a mosaic pattern of acute and organizing diffuse alveolar damage | Modern Rheumatology | 2006 | 30 |
48 | Discontinuation of adalimumab treatment in rheumatoid arthritis patients after achieving low disease activity | Modern Rheumatology | 2012 | 29 |
49 | Age at onset and gender distribution of systemic lupus erythematosus, polymyositis/dermatomyositis, and systemic sclerosis in Japan | Modern Rheumatology | 2013 | 28 |
50 | Post-marketing surveillance of the safety and effectiveness of tacrolimus in 3,267 Japanese patients with rheumatoid arthritis | Modern Rheumatology | 2014 | 28 |