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Top Articles

#TitleJournalYearCitations
1Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trialLancet, The20172,771
2The Global Burden of Cancer 2013JAMA Oncology20152,269
3Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of CirrhosisGastroenterology20132,211
42020 International Society of Hypertension Global Hypertension Practice GuidelinesHypertension20201,895
5Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailtyNature Reviews Cardiology20181,760
6Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017JAMA Oncology20191,691
7Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
8Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research ConsortiumLancet Infectious Diseases, The2019970
9Fungal microbiota dysbiosis in IBDGut2017939
10Tocilizumab in patients with severe COVID-19: a retrospective cohort studyLancet Rheumatology, The2020772
11Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013Journal of Hepatology2014685
12Systemic inflammation in decompensated cirrhosis: Characterization and role in acute‐on‐chronic liver failureHepatology2016550
13European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten‐related disordersUnited European Gastroenterology Journal2019534
14Celiac disease: a comprehensive current reviewBMC Medicine2019529
15Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancerProceedings of the National Academy of Sciences of the United States of America2017502
162020 International Society of Hypertension global hypertension practice guidelinesJournal of Hypertension2020452
17Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ CriteriaNutrients2015423
18Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related DisordersNutrients2013418
19Metroticket 2.0 Model for Analysis of Competing Risks of Death After Liver Transplantation for Hepatocellular CarcinomaGastroenterology2018417
20Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysisGut2018397
21Development of pre and post-operative models to predict early recurrence of hepatocellular carcinoma after surgical resectionJournal of Hepatology2018360
22Molecular Pathways Involved in Colorectal Cancer: Implications for Disease Behavior and PreventionInternational Journal of Molecular Sciences2013354
23Aging and Multimorbidity: New Tasks, Priorities, and Frontiers for Integrated Gerontological and Clinical ResearchJournal of the American Medical Directors Association2015340
24Albumin: Pathophysiologic basis of its role in the treatment of cirrhosis and its complicationsHepatology2013327
25Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2019Endoscopy2019309
26Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis WorldwideGastroenterology2019296
27Tivantinib for second-line treatment of MET-high, advanced hepatocellular carcinoma (METIV-HCC): a final analysis of a phase 3, randomised, placebo-controlled studyLancet Oncology, The2018285
28An International Consortium Update: Pathophysiology, Diagnosis, and Treatment of Polycystic Ovarian Syndrome in AdolescenceHormone Research in Paediatrics2017282
29Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinionIntensive Care Medicine2020278
30Outcomes of sequential treatment with sorafenib followed by regorafenib for HCC: Additional analyses from the phase III RESORCE trialJournal of Hepatology2018270
31An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivityBMC Medicine2014263
32Characteristics, risk factors, and mortality of cirrhotic patients hospitalized for hepatic encephalopathy with and without acute-on-chronic liver failure (ACLF)Journal of Hepatology2014259
33Immune modulation by curcumin: The role of interleukin-10Critical Reviews in Food Science and Nutrition2019259
34HPA axis and aging in depression: Systematic review and meta-analysisPsychoneuroendocrinology2014258
35Esophageal stenting for benign and malignant disease: European Society of Gastrointestinal Endoscopy (ESGE) Clinical GuidelineEndoscopy2016257
36Fungal Dysbiosis in Mucosa-associated Microbiota of Crohn’s Disease PatientsJournal of Crohn's and Colitis2016252
37Coronavirus disease 2019 during pregnancy: a systematic review of reported casesAmerican Journal of Obstetrics and Gynecology2020246
38The Intestinal Microenvironment and Functional Gastrointestinal DisordersGastroenterology2016243
39Enteroendocrine cells: a review of their role in brain–gut communicationNeurogastroenterology and Motility2016241
40Treated Incidence of Psychotic Disorders in the Multinational EU-GEI StudyJAMA Psychiatry2018235
41The endocannabinoid system controls food intake via olfactory processesNature Neuroscience2014229
42Hospital-Acquired Infections in Critically Ill Patients With COVID-19Chest2021225
43Global eradication rates for Helicobacter pylori infection: systematic review and meta-analysis of sequential therapyBMJ, The2013223
44Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLFJournal of Hepatology2020223
45Designing a broad-spectrum integrative approach for cancer prevention and treatmentSeminars in Cancer Biology2015220
46EXCAVATOR: detecting copy number variants from whole-exome sequencing dataGenome Biology2013213
47Dietary linoleic acid and human health: Focus on cardiovascular and cardiometabolic effectsAtherosclerosis2020213
482017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforationWorld Journal of Emergency Surgery2018212
49Clinical outcomes after endoscopic submucosal dissection for colorectal neoplasia: a systematic review and meta-analysisGastrointestinal Endoscopy2017208
50ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian populationEuropean Journal of Human Genetics2020208