# | Title | Journal | Year | Citations |
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1 | Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2017 | 2,771 |
2 | The Global Burden of Cancer 2013 | JAMA Oncology | 2015 | 2,269 |
3 | Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis | Gastroenterology | 2013 | 2,211 |
4 | 2020 International Society of Hypertension Global Hypertension Practice Guidelines | Hypertension | 2020 | 1,895 |
5 | Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty | Nature Reviews Cardiology | 2018 | 1,760 |
6 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
7 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
8 | Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium | Lancet Infectious Diseases, The | 2019 | 970 |
9 | Fungal microbiota dysbiosis in IBD | Gut | 2017 | 939 |
10 | Tocilizumab in patients with severe COVID-19: a retrospective cohort study | Lancet Rheumatology, The | 2020 | 772 |
11 | Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013 | Journal of Hepatology | 2014 | 685 |
12 | Systemic inflammation in decompensated cirrhosis: Characterization and role in acute‐on‐chronic liver failure | Hepatology | 2016 | 550 |
13 | European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten‐related disorders | United European Gastroenterology Journal | 2019 | 534 |
14 | Celiac disease: a comprehensive current review | BMC Medicine | 2019 | 529 |
15 | Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 502 |
16 | 2020 International Society of Hypertension global hypertension practice guidelines | Journal of Hypertension | 2020 | 452 |
17 | Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts’ Criteria | Nutrients | 2015 | 423 |
18 | Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders | Nutrients | 2013 | 418 |
19 | Metroticket 2.0 Model for Analysis of Competing Risks of Death After Liver Transplantation for Hepatocellular Carcinoma | Gastroenterology | 2018 | 417 |
20 | Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis | Gut | 2018 | 397 |
21 | Development of pre and post-operative models to predict early recurrence of hepatocellular carcinoma after surgical resection | Journal of Hepatology | 2018 | 360 |
22 | Molecular Pathways Involved in Colorectal Cancer: Implications for Disease Behavior and Prevention | International Journal of Molecular Sciences | 2013 | 354 |
23 | Aging and Multimorbidity: New Tasks, Priorities, and Frontiers for Integrated Gerontological and Clinical Research | Journal of the American Medical Directors Association | 2015 | 340 |
24 | Albumin: Pathophysiologic basis of its role in the treatment of cirrhosis and its complications | Hepatology | 2013 | 327 |
25 | Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2019 | Endoscopy | 2019 | 309 |
26 | Epidemiology and Effects of Bacterial Infections in Patients With Cirrhosis Worldwide | Gastroenterology | 2019 | 296 |
27 | Tivantinib for second-line treatment of MET-high, advanced hepatocellular carcinoma (METIV-HCC): a final analysis of a phase 3, randomised, placebo-controlled study | Lancet Oncology, The | 2018 | 285 |
28 | An International Consortium Update: Pathophysiology, Diagnosis, and Treatment of Polycystic Ovarian Syndrome in Adolescence | Hormone Research in Paediatrics | 2017 | 282 |
29 | Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion | Intensive Care Medicine | 2020 | 278 |
30 | Outcomes of sequential treatment with sorafenib followed by regorafenib for HCC: Additional analyses from the phase III RESORCE trial | Journal of Hepatology | 2018 | 270 |
31 | An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity | BMC Medicine | 2014 | 263 |
32 | Characteristics, risk factors, and mortality of cirrhotic patients hospitalized for hepatic encephalopathy with and without acute-on-chronic liver failure (ACLF) | Journal of Hepatology | 2014 | 259 |
33 | Immune modulation by curcumin: The role of interleukin-10 | Critical Reviews in Food Science and Nutrition | 2019 | 259 |
34 | HPA axis and aging in depression: Systematic review and meta-analysis | Psychoneuroendocrinology | 2014 | 258 |
35 | Esophageal stenting for benign and malignant disease: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline | Endoscopy | 2016 | 257 |
36 | Fungal Dysbiosis in Mucosa-associated Microbiota of Crohn’s Disease Patients | Journal of Crohn's and Colitis | 2016 | 252 |
37 | Coronavirus disease 2019 during pregnancy: a systematic review of reported cases | American Journal of Obstetrics and Gynecology | 2020 | 246 |
38 | The Intestinal Microenvironment and Functional Gastrointestinal Disorders | Gastroenterology | 2016 | 243 |
39 | Enteroendocrine cells: a review of their role in brain–gut communication | Neurogastroenterology and Motility | 2016 | 241 |
40 | Treated Incidence of Psychotic Disorders in the Multinational EU-GEI Study | JAMA Psychiatry | 2018 | 235 |
41 | The endocannabinoid system controls food intake via olfactory processes | Nature Neuroscience | 2014 | 229 |
42 | Hospital-Acquired Infections in Critically Ill Patients With COVID-19 | Chest | 2021 | 225 |
43 | Global eradication rates for Helicobacter pylori infection: systematic review and meta-analysis of sequential therapy | BMJ, The | 2013 | 223 |
44 | Blood metabolomics uncovers inflammation-associated mitochondrial dysfunction as a potential mechanism underlying ACLF | Journal of Hepatology | 2020 | 223 |
45 | Designing a broad-spectrum integrative approach for cancer prevention and treatment | Seminars in Cancer Biology | 2015 | 220 |
46 | EXCAVATOR: detecting copy number variants from whole-exome sequencing data | Genome Biology | 2013 | 213 |
47 | Dietary linoleic acid and human health: Focus on cardiovascular and cardiometabolic effects | Atherosclerosis | 2020 | 213 |
48 | 2017 WSES guidelines on colon and rectal cancer emergencies: obstruction and perforation | World Journal of Emergency Surgery | 2018 | 212 |
49 | Clinical outcomes after endoscopic submucosal dissection for colorectal neoplasia: a systematic review and meta-analysis | Gastrointestinal Endoscopy | 2017 | 208 |
50 | ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population | European Journal of Human Genetics | 2020 | 208 |