| # | Title | Journal | Year | Citations |
|---|
| 1 | 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation | Heart Rhythm | 2017 | 1,671 |
| 2 | 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation | Europace | 2018 | 767 |
| 3 | Cellular and Molecular Basis of Pulmonary Arterial Hypertension | Journal of the American College of Cardiology | 2009 | 714 |
| 4 | Long-term prognostic value of resting heart rate in patients with suspected or proven coronary artery disease | European Heart Journal | 2005 | 694 |
| 5 | Ionic Remodeling Underlying Action Potential Changes in a Canine Model of Atrial Fibrillation | Circulation Research | 1997 | 659 |
| 6 | Effects of Angiotensin-Converting Enzyme Inhibition on the Development of the Atrial Fibrillation Substrate in Dogs With Ventricular Tachypacing–Induced Congestive Heart Failure | Circulation | 2001 | 646 |
| 7 | Probucol and Multivitamins in the Prevention of Restenosis after Coronary Angioplasty | New England Journal of Medicine | 1997 | 578 |
| 8 | Enalapril Decreases the Incidence of Atrial Fibrillation in Patients With Left Ventricular Dysfunction | Circulation | 2003 | 549 |
| 9 | Sustained depolarization-induced outward current in human atrial myocytes. Evidence for a novel delayed rectifier K+ current similar to Kv1.5 cloned channel currents. | Circulation Research | 1993 | 537 |
| 10 | Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression | Circulation Research | 2014 | 530 |
| 11 | Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial | Lancet, The | 2004 | 468 |
| 12 | Lower Incidence of Thrombus Formation With Cryoenergy Versus Radiofrequency Catheter Ablation | Circulation | 2003 | 464 |
| 13 | Evidence for Two Components of Delayed Rectifier K + Current in Human Ventricular Myocytes | Circulation Research | 1996 | 409 |
| 14 | Cellular and Molecular Mechanisms of Atrial Arrhythmogenesis in Patients With Paroxysmal Atrial Fibrillation | Circulation | 2014 | 386 |
| 15 | 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary | Europace | 2018 | 375 |
| 16 | Prognostic importance of a clinical profile and exercise test in medically treated patients with coronary artery disease | Journal of the American College of Cardiology | 1984 | 370 |
| 17 | A controlled clinical trial to assess the effect of a calcium channel blocker on the progression of coronary atherosclerosis. | Circulation | 1990 | 368 |
| 18 | Hyperlipidemia and Coronary Disease | Circulation | 1995 | 357 |
| 19 | Effects of Experimental Heart Failure on Atrial Cellular and Ionic Electrophysiology | Circulation | 2000 | 356 |
| 20 | 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary | Journal of Arrhythmia | 2017 | 348 |
| 21 | Cryoballoon or Radiofrequency Ablation for Atrial Fibrillation Assessed by Continuous Monitoring | Circulation | 2019 | 345 |
| 22 | Progression to chronic atrial fibrillation after the initial diagnosis of paroxysmal atrial fibrillation: Results from the Canadian Registry of Atrial Fibrillation | American Heart Journal | 2005 | 317 |
| 23 | Aspirin versus heparin to prevent myocardial infarction during the acute phase of unstable angina. | Circulation | 1993 | 292 |
| 24 | Prognostic significance of progression of coronary atherosclerosis. | Circulation | 1993 | 285 |
| 25 | Human Pulmonary Circulation Is an Important Site for Both Clearance and Production of Endothelin-1 | Circulation | 1996 | 258 |
| 26 | Pulmonary clearance of circulating endothelin-1 in dogs in vivo: exclusive role of ETBreceptors | Journal of Applied Physiology | 1996 | 254 |
| 27 | Characterization of a transient outward K+ current with inward rectification in canine ventricular myocytes | American Journal of Physiology - Cell Physiology | 1998 | 251 |
| 28 | Effect of Simvastatin and Antioxidant Vitamins on Atrial Fibrillation Promotion by Atrial-Tachycardia Remodeling in Dogs | Circulation | 2004 | 249 |
| 29 | Myocardial infarction patients in the 1990s—their risk factors, stratification and survival in Canada: The Canadian assessment of myocardial infarction (CAMI) study | Journal of the American College of Cardiology | 1996 | 241 |
| 30 | Differing sympathetic and vagal effects on atrial fibrillation in dogs: role of refractoriness heterogeneity | American Journal of Physiology - Heart and Circulatory Physiology | 1997 | 236 |
| 31 | VEGF Gene Therapy Fails to Improve Perfusion of Ischemic Myocardium in Patients With Advanced Coronary Disease: Results of the NORTHERN Trial | Molecular Therapy | 2009 | 232 |
| 32 | Additive Beneficial Effects of Beta-Blockers to Angiotensin-Converting Enzyme Inhibitors in the Survival and Ventricular Enlargement (SAVE) Study fn1fn1This study was supported by a University-Industry grant from the Medical Research Council, Ottawa, Ontario, Canada and Bristol Myers Squibb, Montreal, Quebec, Canada. | Journal of the American College of Cardiology | 1997 | 231 |
| 33 | Enalapril Reduces the Incidence of Diabetes in Patients With Chronic Heart Failure | Circulation | 2003 | 230 |
| 34 | Management of coronary artery disease: therapeutic options in patients with diabetes | Journal of the American College of Cardiology | 2000 | 229 |
| 35 | Dynamic Nature of Atrial Fibrillation Substrate During Development and Reversal of Heart Failure in Dogs | Circulation | 2002 | 226 |
| 36 | Evolution, mechanisms, and classification of antiarrhythmic drugs: focus on class III actions | American Journal of Cardiology | 1999 | 222 |
| 37 | Rapid and slow components of delayed rectifier current in human atrial myocytes | Cardiovascular Research | 1994 | 218 |
| 38 | Myocardial function during atrial pacing in patients with angina pectoris and normal coronary arteriograms | American Journal of Cardiology | 1973 | 215 |
| 39 | Enalapril effects on atrial remodeling and atrial fibrillation in experimental congestive heart failure | Cardiovascular Research | 2002 | 214 |
| 40 | Mechanisms of Atrial Fibrillation: Lessons From Animal Models | Progress in Cardiovascular Diseases | 2005 | 213 |
| 41 | Antithrombotic Therapy in Patients With Atrial Fibrillation Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention | Circulation | 2018 | 211 |
| 42 | Cigarette Smoking Acutely Increases Platelet Thrombus Formation in Patients With Coronary Artery Disease Taking Aspirin | Circulation | 1995 | 211 |
| 43 | Mechanism of flecainide's antiarrhythmic action in experimental atrial fibrillation. | Circulation Research | 1992 | 209 |
| 44 | Tachycardia-Induced Changes in Na + Current in a Chronic Dog Model of Atrial Fibrillation | Circulation Research | 1997 | 209 |
| 45 | Angiotensin Receptor Blockade and Exercise Capacity in Adults With Systemic Right Ventricles | Circulation | 2005 | 208 |
| 46 | Contrast-Induced Nephropathy: From Pathophysiology to Preventive Strategies | Canadian Journal of Cardiology | 2016 | 206 |
| 47 | Comparative mechanisms of antiarrhythmic drug action in experimental atrial fibrillation. Importance of use-dependent effects on refractoriness. | Circulation | 1993 | 197 |
| 48 | Pulmonary Vein Region Ablation in Experimental Vagal Atrial Fibrillation | Circulation | 2008 | 196 |
| 49 | Potential Molecular Basis of Different Physiological Properties of the Transient Outward K + Current in Rabbit and Human Atrial Myocytes | Circulation Research | 1999 | 193 |
| 50 | Delayed rectifier outward current and repolarization in human atrial myocytes. | Circulation Research | 1993 | 180 |
