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| Standardization of intravenous insulin therapy improves the efficiency and safety of blood glucose control in critically ill adults | Intensive Care Medicine | 2004 | 201 |
| Prophylactic vaccination against human papillomavirus infection and disease in women: a systematic review of randomized controlled trials | Cmaj | 2007 | 114 |
| Suffering with advanced cancer | Journal of Clinical Oncology | 2007 | 109 |
| The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis | Critical Care Medicine | 2015 | 104 |
| Self-reported barriers and facilitators to preventive human papillomavirus vaccination among adolescent girls and young women: a systematic review | Preventive Medicine | 2014 | 97 |
| Evaluating the use of Drotrecogin alfa (activated) in adult severe sepsis: a Canadian multicenter observational study | Intensive Care Medicine | 2007 | 70 |
| Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement | Clinical Pharmacokinetics | 2015 | 64 |
| Efficacy and safety of dopamine agonists in traumatic brain injury: a systematic review of randomized controlled trials | Journal of Neurotrauma | 2012 | 62 |
| Systematic review of physical and chemical compatibility of commonly used medications administered by continuous infusion in intensive care units | Critical Care Medicine | 2010 | 61 |
| The pharmacokinetics of nelfinavir and M8 during pregnancy and post partum | Clinical Pharmacology and Therapeutics | 2004 | 58 |
| Cardiac glycoside toxicity: more than 200 years and counting | Critical Care Clinics | 2012 | 57 |
| Treating an established episode of delirium in palliative care: expert opinion and review of the current evidence base with recommendations for future development | Journal of Pain and Symptom Management | 2014 | 55 |
| Deprescribing versus continuation of chronic proton pump inhibitor use in adults | The Cochrane Library | 2017 | 53 |
| Pharmacokinetic interaction between mefloquine and ritonavir in healthy volunteers | British Journal of Clinical Pharmacology | 2001 | 52 |
| Time-dependent interaction between lopinavir/ritonavir and fexofenadine | Journal of Clinical Pharmacology | 2006 | 50 |
| Myasthenia Gravis Treated With Autologous Hematopoietic Stem Cell Transplantation | JAMA Neurology | 2016 | 46 |
| An evaluation of the management of asymptomatic catheter-associated bacteriuria and candiduria at The Ottawa Hospital | Canadian Journal of Infectious Diseases and Medical Microbiology | 2005 | 45 |
| Adherence to simple and effective measures reduces the incidence of ventilator-associated pneumonia | Canadian Journal of Anaesthesia | 2005 | 44 |
| Pharmacoepidemiology of stress ulcer prophylaxis in the United States and Canada | Journal of Critical Care | 2014 | 38 |
| Acquisition of metastatic tissue from patients with bone metastases from breast cancer | Breast Cancer Research and Treatment | 2011 | 37 |
| Validation of the Critical Care Pain Observation Tool in Critically Ill Patients With Delirium: A Prospective Cohort Study | Critical Care Medicine | 2016 | 37 |
| The Effect of Renal Replacement Therapy and Antibiotic Dose on Antibiotic Concentrations in Critically Ill Patients: Data From the Multinational Sampling Antibiotics in Renal Replacement Therapy Study | Clinical Infectious Diseases | 2021 | 37 |
| Incidence, causes, and consequences of preventable adverse drug reactions occurring in inpatients: A systematic review of systematic reviews | PLoS ONE | 2018 | 37 |
| Impaired gastrointestinal transit and its associated morbidity in the intensive care unit | Journal of Critical Care | 2013 | 36 |
