795(top 1%)
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Top Articles

#TitleJournalYearCitations
1Evaluation of D-Dimer in the Diagnosis of Suspected Deep-Vein ThrombosisNew England Journal of Medicine20031,329
2Continuous glucose monitoring in pregnant women with type 1 diabetes (CONCEPTT): a multicentre international randomised controlled trialLancet, The2017469
3YouTube as a source of information on COVID-19: a pandemic of misinformation?BMJ Global Health2020417
4Socioeconomic status and risk of cardiovascular disease in 20 low-income, middle-income, and high-income countries: the Prospective Urban Rural Epidemiologic (PURE) studyThe Lancet Global Health2019340
5Increasing Incidence of Chronic Graft-versus-Host Disease in Allogeneic Transplantation: A Report from the Center for International Blood and Marrow Transplant ResearchBiology of Blood and Marrow Transplantation2015331
6Prolonged Therapeutic Hypothermia After Traumatic Brain Injury in AdultsJAMA - Journal of the American Medical Association2003316
7Time-dependent bias was common in survival analyses published in leading clinical journalsJournal of Clinical Epidemiology2004312
8Multiple Combination Bactericidal Testing of Staphylococcal Biofilms from Implant-Associated InfectionsAntimicrobial Agents and Chemotherapy2006282
9Pulmonary embolism in pregnancyLancet, The2010258
10A Patient Decision Aid Regarding Antithrombotic Therapy for Stroke Prevention in Atrial FibrillationA Randomized Controlled TrialJAMA - Journal of the American Medical Association1999246
11Systematic review and meta-analysis of incidence, prevalence and outcomes of atrial fibrillation in patients on dialysisNephrology Dialysis Transplantation2012243
12Etidronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal womenThe Cochrane Library2008237
13Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trialsBMJ: British Medical Journal1999220
14Permeability barrier dysfunction in transgenic mice overexpressing claudin 6Development (Cambridge)2002203
15Dalteparin for the prevention of recurrence of placental-mediated complications of pregnancy in women without thrombophilia: a pilot randomized controlled trialJournal of Thrombosis and Haemostasis2009201
16Plasma PCSK9 levels are significantly modified by statins and fibrates in humansLipids in Health and Disease2008187
17Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysmNature Genetics2010181
18Angiotensin-(1–7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cellsKidney International2006171
19Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal womenThe Cochrane Library2008169
20Executive summary of the KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney DiseaseKidney International2021169
21Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority studyAnnals of Oncology2008163
22Integrated strategies for the diagnosis of venous thromboembolismJournal of Thrombosis and Haemostasis2007162
23Clinical improvement as reflected in measures of function and health-related quality of life following treatment with leflunomide compared with methotrexate in patients with rheumatoid arthritis: Sensitivity and relative efficiency to detect a treatment effect in a twelve-month, placebo-controlled trialArthritis and Rheumatism2000155
24Exclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysisBMJ, The2014154
25Atrioventricular Block as the Initial Manifestation of Cardiac Sarcoidosis in Middle‐Aged AdultsJournal of Cardiovascular Electrophysiology2014150
26A novel locus for inherited myoclonus-dystonia on 18p11Neurology2002140
27Focal and Segmental Glomerulosclerosis in Mice with Podocyte-Specific Expression of Mutant α-Actinin-4Journal of the American Society of Nephrology: JASN2003140
28Time course and pattern of COPD exacerbation onsetThorax2012139
29Severe Group A Streptococcal Soft-Tissue Infections in Ontario: 1992–1996Clinical Infectious Diseases2002136
30A systematic review of contact dermatitis treatment and preventionJournal of the American Academy of Dermatology2005131
31The Geriatrics 5M's: A New Way of Communicating What We DoJournal of the American Geriatrics Society2017127
32Fluoride for the Treatment of Postmenopausal Osteoporotic Fractures: A Meta-AnalysisOsteoporosis International2000122
33The role of angiotensin converting enzyme 2 in the generation of angiotensin 1–7 by rat proximal tubulesAmerican Journal of Physiology - Renal Physiology2005119
34Management of adverse effects of Peg-IFN and ribavirin therapy for hepatitis CNature Reviews Gastroenterology and Hepatology2011119
35Axicabtagene ciloleucel as first-line therapy in high-risk large B-cell lymphoma: the phase 2 ZUMA-12 trialNature Medicine2022114
36A pilot randomized trial of adjuvant rituximab or placebo for nonsplenectomized patients with immune thrombocytopeniaBlood2012111
37Risk of post‐thrombotic syndrome after subtherapeutic warfarin anticoagulation for a first unprovoked deep vein thrombosis: results from the REVERSE studyJournal of Thrombosis and Haemostasis2012110
38A Role for DNA Methylation in Gastrulation and Somite PatterningDevelopmental Biology1999109
39Home Mechanical Ventilation in Canada: A National SurveyRespiratory Care2015107
40Rapamycin Inhibits Human Adipocyte Differentiation in Primary CultureObesity2000102
41Novel Loss-of-Function PCSK9 Variant Is Associated with Low Plasma LDL Cholesterol in a French-Canadian Family and with Impaired Processing and Secretion in Cell CultureClinical Chemistry2011101
42What Is Necessary for High-Quality Discharge Summaries?American Journal of Medical Quality199999
43Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV‐1 reservoirs: results from a multicentre randomized clinical studyHIV Medicine201299
44Low level laser therapy (Classes I, II and III) for treating rheumatoid arthritisThe Cochrane Library200598
45The obesity paradox in community-acquired bacterial pneumoniaInternational Journal of Infectious Diseases201197
46Tai chi for treating rheumatoid arthritisThe Cochrane Library200496
47Prevalence of Cardiac Sarcoidosis in Patients Presenting with Monomorphic Ventricular TachycardiaPACE - Pacing and Clinical Electrophysiology201496
48Shelter-based managed alcohol administration to chronicallyhomeless people addicted to alcoholCmaj200695
49Transcutaneous electrical nerve stimulation (TENS) for the treatment of rheumatoid arthritis in the handThe Cochrane Library200394
50Calcium and vitamin D for corticosteroid-induced osteoporosisThe Cochrane Library199893