| # | Title | Journal | Year | Citations |
|---|
| 1 | Oral antihyperglycemic therapy for type 2 diabetes mellitus | Cmaj | 2005 | 354 |
| 2 | GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 316 |
| 3 | Interaction between colonic acetate and propionate in humans | American Journal of Clinical Nutrition | 1991 | 281 |
| 4 | Parathyroid Hormone Secretion and Action: Evidence for Discrete Receptors for the Carboxyl-Terminal Region and Related Biological Actions of Carboxyl-Terminal Ligands | Endocrine Reviews | 2005 | 276 |
| 5 | Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system | Cell Metabolism | 2006 | 257 |
| 6 | THE GLYCAEMIC RESPONSE TO CARBOHYDRATE FOODS | Lancet, The | 1984 | 238 |
| 7 | Bempedoic acid plus ezetimibe fixed-dose combination in patients with hypercholesterolemia and high CVD risk treated with maximally tolerated statin therapy | European Journal of Preventive Cardiology | 2020 | 224 |
| 8 | Beneficial Effect of a Low Glycaemic Index Diet in Type 2 Diabetes | Diabetic Medicine | 1992 | 221 |
| 9 | Starchy Foods and Glycemic Index | Diabetes Care | 1988 | 212 |
| 10 | Canagliflozin Provides Durable Glycemic Improvements and Body Weight Reduction Over 104 Weeks Versus Glimepiride in Patients With Type 2 Diabetes on Metformin: A Randomized, Double-Blind, Phase 3 Study | Diabetes Care | 2015 | 197 |
| 11 | Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus | JAMA Cardiology | 2016 | 196 |
| 12 | Advancing Basal Insulin Replacement in Type 2 Diabetes Inadequately Controlled With Insulin Glargine Plus Oral Agents: A Comparison of Adding Albiglutide, a Weekly GLP-1 Receptor Agonist, Versus Thrice-Daily Prandial Insulin Lispro | Diabetes Care | 2014 | 186 |
| 13 | Effects of canagliflozin versus glimepiride on adipokines and inflammatory biomarkers in type 2 diabetes | Metabolism: Clinical and Experimental | 2018 | 180 |
| 14 | Almonds Decrease Postprandial Glycemia, Insulinemia, and Oxidative Damage in Healthy Individuals | Journal of Nutrition | 2006 | 172 |
| 15 | Glycemic Response to Wheat Products: Reduced Response to Pasta but No Effect of Fiber | Diabetes Care | 1983 | 169 |
| 16 | A dietary portfolio approach to cholesterol reduction: Combined effects of plant sterols, vegetable proteins, and viscous fibers in hypercholesterolemia | Metabolism: Clinical and Experimental | 2002 | 159 |
| 17 | Cortical PQCT Measures Are Associated With Fractures in Dialysis Patients | Journal of Bone and Mineral Research | 2006 | 158 |
| 18 | Effects of dietary pulse consumption on body weight: a systematic review and meta-analysis of randomized controlled trials | American Journal of Clinical Nutrition | 2016 | 150 |
| 19 | Effects of high- and low-isoflavone (phytoestrogen) soy foods on inflammatory biomarkers and proinflammatory cytokines in middle-aged men and women | Metabolism: Clinical and Experimental | 2002 | 135 |
| 20 | Metabolic Effects of Reducing Rate of Glucose Ingestion by Single Bolus Versus Continuous Sipping | Diabetes | 1990 | 129 |
| 21 | The 2011 Canadian Hypertension Education Program Recommendations for the Management of Hypertension: Blood Pressure Measurement, Diagnosis, Assessment of Risk, and Therapy | Canadian Journal of Cardiology | 2011 | 127 |
| 22 | Effect of an siRNA Therapeutic Targeting PCSK9 on Atherogenic Lipoproteins | Circulation | 2018 | 127 |
| 23 | Effect of a very-high-fiber vegetable, fruit, and nut diet on serum lipids and colonic function | Metabolism: Clinical and Experimental | 2001 | 124 |
| 24 | Lycopene consumption decreases oxidative stress and bone resorption markers in postmenopausal women | Osteoporosis International | 2007 | 122 |
| 25 | Metabolic advantages of spreading the nutrient load: effects of increased meal frequency in non-insulin-dependent diabetes | American Journal of Clinical Nutrition | 1992 | 106 |
| 26 | Low glycemic index: lente carbohydrates and physiological effects of altered food frequency | American Journal of Clinical Nutrition | 1994 | 105 |
| 27 | Epigallocatechin-3-gallate increases the formation of mineralized bone nodules by human osteoblast-like cells | Journal of Nutritional Biochemistry | 2007 | 103 |
| 28 | Standards and Guidelines for Performing Central Dual-Energy X-Ray Absorptiometry in Premenopausal Women, Men, and ChildrenA Report From the Canadian Panel† of the International Society of Clinical Densitometry | Journal of Clinical Densitometry | 2004 | 101 |
| 29 | Supplementation with the antioxidant lycopene significantly decreases oxidative stress parameters and the bone resorption marker N-telopeptide of type I collagen in postmenopausal women | Osteoporosis International | 2011 | 99 |
| 30 | High-protein diets in hyperlipidemia: effect of wheat gluten on serum lipids, uric acid, and renal function | American Journal of Clinical Nutrition | 2001 | 94 |
| 31 | Glycemic Response to Pasta: Effect of Surface Area, Degree of Cooking, and Protein Enrichment | Diabetes Care | 1986 | 90 |
| 32 | Time of day and glucose tolerance status affect serum short-chain fatty concentrations in humans | Metabolism: Clinical and Experimental | 1997 | 88 |
| 33 | Starchy foods and fiber: reduced rate of digestion and improved carbohydrate metabolism | Scandinavian Journal of Gastroenterology | 1987 | 84 |
| 34 | Pseudohypoparathyroidism with osteitis fibrosa cystica: Direct demonstration of skeletal responsiveness to parathyroid hormone in cells cultured from bone | Journal of Bone and Mineral Research | 1993 | 83 |
| 35 | HUMAN PARATHYROID HORMONE CARBOXYTERMINAL PEPTIDE (53-84) STIMULATES ALKALINE PHOSPHATASE ACTIVITY IN DEXAMETHASONE-TREATED RAT OSTEOSARCOMA CELLS IN VITRO | Endocrinology | 1989 | 78 |
| 36 | Butyrate modulates TGF-β1 generation and function: Potential renal benefit for Acacia(sen) SUPERGUM™ (gum arabic)? | Kidney International | 2006 | 78 |
| 37 | Specific types of colonic fermentation may raise low-density-lipoprotein-cholesterol concentrations | American Journal of Clinical Nutrition | 1991 | 75 |
| 38 | Efficacy and Safety of the Once-Weekly GLP-1 Receptor Agonist Albiglutide Versus Sitagliptin in Patients With Type 2 Diabetes and Renal Impairment: A Randomized Phase III Study | Diabetes Care | 2014 | 75 |
| 39 | Isosorbide Mononitrate Increases Bone Formation and Decreases Bone Resorption in Postmenopausal Women: A Randomized Trial | Journal of Bone and Mineral Research | 2004 | 74 |
| 40 | Efficacy and Safety of Saxagliptin in Older Participants in the SAVOR-TIMI 53 Trial | Diabetes Care | 2015 | 73 |
| 41 | Comparison of high- and low-glycemic-index breakfast cereals with monounsaturated fat in the long-term dietary management of type 2 diabetes | American Journal of Clinical Nutrition | 2000 | 72 |
| 42 | Impaired muscle strength is associated with fractures in hemodialysis patients | Osteoporosis International | 2006 | 71 |
| 43 | Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: a post hoc analysis of gender, age, and baseline CV risk profile in the SUSTAIN 6 trial | Cardiovascular Diabetology | 2019 | 69 |
| 44 | Association of Lipoprotein(a) With Risk of Recurrent Ischemic Events Following Acute Coronary Syndrome | JAMA Cardiology | 2018 | 68 |
| 45 | Time Trends and Geographic Disparities in Acute Complications of Diabetes in Ontario, Canada | Diabetes Care | 2005 | 67 |
| 46 | Plasmid-based gene therapy of diabetes mellitus | Gene Therapy | 2007 | 66 |
| 47 | The Glycemic Index: Flogging a Dead Horse? | Diabetes Care | 1997 | 64 |
| 48 | Direct comparison of dietary portfolio vs statin on C-reactive protein | European Journal of Clinical Nutrition | 2005 | 64 |
| 49 | Glycemic Index of Foods in Individual Subjects | Diabetes Care | 1990 | 63 |
| 50 | Clinical utility of laboratory testing in women with osteoporosis | Osteoporosis International | 2005 | 60 |
