| # | Title | Journal | Year | Citations |
|---|
| 1 | The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia | Blood | 2016 | 7,429 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes | Blood | 2009 | 3,864 |
| 4 | Intestinal mucosal barrier function in health and disease | Nature Reviews Immunology | 2009 | 2,795 |
| 5 | Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy | Science | 2015 | 2,782 |
| 6 | Flow-mediated endothelial mechanotransduction | Physiological Reviews | 1995 | 2,502 |
| 7 | CD28/B7 SYSTEM OF T CELL COSTIMULATION | Annual Review of Immunology | 1996 | 2,466 |
| 8 | The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma | American Journal of Surgical Pathology | 2005 | 2,334 |
| 9 | Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity | Nature | 2015 | 2,130 |
| 10 | The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients | Science | 2018 | 2,027 |
| 11 | The Biology of NKT Cells | Annual Review of Immunology | 2007 | 1,961 |
| 12 | The World Health Organization (WHO) classification of the myeloid neoplasms | Blood | 2002 | 1,899 |
| 13 | B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes | Immunity | 2000 | 1,884 |
| 14 | Innate immunity and intestinal microbiota in the development of Type 1 diabetes | Nature | 2008 | 1,745 |
| 15 | Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth | Nature Medicine | 2011 | 1,740 |
| 16 | Amino acid analysis by reverse-phase high-performance liquid chromatography: Precolumn derivatization with phenylisothiocyanate | Analytical Biochemistry | 1984 | 1,630 |
| 17 | STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors | Immunity | 2014 | 1,468 |
| 18 | Up-Regulation of PD-L1, IDO, and T regs in the Melanoma Tumor Microenvironment Is Driven by CD8 + T Cells | Science Translational Medicine | 2013 | 1,447 |
| 19 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 20 | Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages | Science | 1994 | 1,400 |
| 21 | The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota | Science | 2011 | 1,354 |
| 22 | STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors | Immunity | 2014 | 1,325 |
| 23 | Loss of PTEN Promotes Resistance to T Cell–Mediated Immunotherapy | Cancer Discovery | 2016 | 1,158 |
| 24 | Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment | Blood | 2009 | 1,146 |
| 25 | FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6 -Methyladenosine RNA Demethylase | Cancer Cell | 2017 | 1,139 |
| 26 | Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg | Science | 1992 | 1,119 |
| 27 | Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity | Cell Reports | 2015 | 1,083 |
| 28 | Diagnostic criteria and classification of mastocytosis: a consensus proposal | Leukemia Research | 2001 | 1,020 |
| 29 | Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy | Cancer Cell | 2017 | 1,011 |
| 30 | Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors | Genome Biology | 2007 | 1,009 |
| 31 | COMPLEXITIES OF CD28/B7: CTLA-4 COSTIMULATORY PATHWAYS IN AUTOIMMUNITY AND TRANSPLANTATION | Annual Review of Immunology | 2001 | 973 |
| 32 | Distribution of cholinergic neurons in rat brain: Demonstrated by the immunocytochemical localization of choline acetyltransferase | Journal of Comparative Neurology | 1983 | 934 |
| 33 | Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment | Cancer Research | 2009 | 911 |
| 34 | Classification and diagnosis of myeloproliferative neoplasms: The 2008 World Health Organization criteria and point-of-care diagnostic algorithms | Leukemia | 2008 | 908 |
| 35 | Lysosomal Glycosphingolipid Recognition by NKT Cells | Science | 2004 | 880 |
| 36 | Protein disaggregation mediated by heat-shock protein Hspl04 | Nature | 1994 | 862 |
| 37 | Kinetic proofreading in T-cell receptor signal transduction. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 829 |
| 38 | Tracking the Response of Natural Killer T Cells to a Glycolipid Antigen Using Cd1d Tetramers | Journal of Experimental Medicine | 2000 | 818 |
| 39 | Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: A synopsis of the National Cancer Institute Thyroid Fine‐Needle Aspiration State of the Science Conference | Diagnostic Cytopathology | 2008 | 816 |
| 40 | Stabilization of wild-type p53 by hypoxia-inducible factor 1α | Nature | 1998 | 804 |
| 41 | Helper T Cell Differentiation Is Controlled by the Cell Cycle | Immunity | 1998 | 786 |
| 42 | The intestinal epithelial barrier: a therapeutic target? | Nature Reviews Gastroenterology and Hepatology | 2017 | 786 |
| 43 | Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries | Archives of Pathology and Laboratory Medicine | 1988 | 760 |
| 44 | CTLA-4 ligation blocks CD28-dependent T cell activation. | Journal of Experimental Medicine | 1996 | 732 |
| 45 | Gender Bias in Autoimmunity Is Influenced by Microbiota | Immunity | 2013 | 730 |
| 46 | Coordinated Induction by IL15 of a TCR-Independent NKG2D Signaling Pathway Converts CTL into Lymphokine-Activated Killer Cells in Celiac Disease | Immunity | 2004 | 723 |
| 47 | Tight Junction Pore and Leak Pathways: A Dynamic Duo | Annual Review of Physiology | 2011 | 720 |
| 48 | Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT | Nature | 1997 | 704 |
| 49 | The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells | Immunity | 2012 | 694 |
| 50 | Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome | Nature Genetics | 2002 | 692 |
