| # | Title | Journal | Year | Citations |
|---|
| 1 | Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells | Cell | 2014 | 375 |
| 2 | Pathobiology of transforming growth factor β in cancer, fibrosis and immunologic disease, and therapeutic considerations | Laboratory Investigation | 2007 | 370 |
| 3 | Multiple infections in carotid atherosclerotic plaques | American Heart Journal | 1999 | 352 |
| 4 | GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 316 |
| 5 | Aggressive pituitary adenomas—diagnosis and emerging treatments | Nature Reviews Endocrinology | 2014 | 239 |
| 6 | Intravenous immunoglobulin ameliorates ITP via activating Fcγ receptors on dendritic cells | Nature Medicine | 2006 | 232 |
| 7 | Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents | Blood | 2018 | 231 |
| 8 | Identification of an innate T helper type 17 response to intestinal bacterial pathogens | Nature Medicine | 2011 | 216 |
| 9 | Neuropilin-1 is a receptor for transforming growth factor β-1, activates its latent form, and promotes regulatory T cell activity | Journal of Leukocyte Biology | 2008 | 212 |
| 10 | Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations | Acta Neuropathologica | 2014 | 211 |
| 11 | Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond | Critical Reviews in Clinical Laboratory Sciences | 2016 | 211 |
| 12 | Glypican-3 expression in hepatocellular tumors: diagnostic value for preneoplastic lesions and hepatocellular carcinomas | Human Pathology | 2006 | 208 |
| 13 | Endoglin (CD105): a review of its role in angiogenesis and tumor diagnosis, progression and therapy | Anticancer Research | 2011 | 195 |
| 14 | Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection | Cell Metabolism | 2018 | 188 |
| 15 | Clinical evaluation of microRNA expression profiling in non small cell lung cancer | Lung Cancer | 2013 | 179 |
| 16 | Metastamirs: a stepping stone towards improved cancer management | Nature Reviews Clinical Oncology | 2011 | 174 |
| 17 | Electroporation-Enhanced Nonviral Gene Transfer for the Prevention or Treatment of Immunological, Endocrine and Neoplastic Diseases | Current Gene Therapy | 2006 | 173 |
| 18 | miRNA Profiling for Clear Cell Renal Cell Carcinoma: Biomarker Discovery and Identification of Potential Controls and Consequences of miRNA Dysregulation | Journal of Urology | 2011 | 172 |
| 19 | HER2 and TOP2A as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: a meta-analysis of individual patient data | Lancet Oncology, The | 2011 | 165 |
| 20 | Thrombin-triggered platelet apoptosis | Journal of Thrombosis and Haemostasis | 2006 | 160 |
| 21 | Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta | Carcinogenesis | 2011 | 153 |
| 22 | Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapies | Thrombosis Journal | 2016 | 141 |
| 23 | Crosstalk between Platelets and the Immune System: Old Systems with New Discoveries | Advances in Hematology | 2012 | 123 |
| 24 | Platelet-bound lipopolysaccharide enhances Fc receptor–mediated phagocytosis of IgG-opsonized platelets | Blood | 2007 | 122 |
| 25 | Cancer Stem Cells and Novel Targets for Antitumor Strategies | Current Pharmaceutical Design | 2012 | 121 |
| 26 | Breast Cancer Stem-Like Cells Are Inhibited by a Non-Toxic Aryl Hydrocarbon Receptor Agonist | PLoS ONE | 2010 | 117 |
| 27 | Microvessel density in pituitary adenomas and carcinomas | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2001 | 116 |
| 28 | MicroRNAs as Regulators of Signal Transduction in Urological Tumors | Clinical Chemistry | 2011 | 113 |
| 29 | Silent subtype 3 pituitary adenoma: a clinicopathologic analysis of the Mayo Clinic experience | Clinical Endocrinology | 2009 | 112 |
| 30 | Nod1 and Nod2 Regulation of Inflammation in the Salmonella Colitis Model | Infection and Immunity | 2010 | 109 |
| 31 | The Clinical Utility of miR-21 as a Diagnostic and Prognostic Marker for Renal Cell Carcinoma | Journal of Molecular Diagnostics | 2012 | 106 |
| 32 | Histogram flow mapping with optical coherence tomography for in vivo skin angiography of hereditary hemorrhagic telangiectasia | Journal of Biomedical Optics | 2014 | 106 |
| 33 | The translational potential of microRNAs as biofluid markers of urological tumours | Nature Reviews Urology | 2016 | 104 |
| 34 | Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories | Journal of Clinical Virology | 2020 | 102 |
| 35 | Role of MGMT in tumor development, progression, diagnosis, treatment and prognosis | Anticancer Research | 2009 | 101 |
| 36 | Platelets in hemostasis and thrombosis: Novel mechanisms of fibrinogen-independent platelet aggregation and fibronectinmediated protein wave of hemostasis | Journal of Biomedical Research | 2015 | 100 |
| 37 | Pituitary hyperplasia | Pituitary | 1999 | 99 |
| 38 | Temozolomide therapy in a man with an aggressive prolactin-secreting pituitary neoplasm: morphological findings | Human Pathology | 2007 | 96 |
| 39 | Treatment of pituitary neoplasms with temozolomide | Cancer | 2011 | 94 |
| 40 | Diagnostic, prognostic and therapeutic implications of microRNAs in urologic tumors | Nature Reviews Urology | 2010 | 93 |
| 41 | T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10 | Blood | 2017 | 93 |
| 42 | The impact of adoption of the International Association of Diabetes in Pregnancy Study Group criteria for the screening and diagnosis of gestational diabetes | American Journal of Obstetrics and Gynecology | 2015 | 92 |
| 43 | Antitumour effects of temozolomide in a man with a large, invasive prolactin-producing pituitary neoplasm | Clinical Endocrinology | 2006 | 90 |
| 44 | Transdifferentiation of somatotrophs to thyrotrophs in the pituitary of patients with protracted primary hypothyroidism | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2000 | 88 |
| 45 | Dopamine D2 Receptor Gene Expression in Human Adenohypophysial Adenomas | Endocrine | 2001 | 87 |
| 46 | Reversible Transdifferentiation: Interconversion of Somatotrophs and Lactotrophs in Pituitary Hyperplasia | Modern Pathology | 2001 | 87 |
| 47 | Quantitative proteomic analysis reveals potential diagnostic markers and pathways involved in pathogenesis of renal cell carcinoma | Oncotarget | 2014 | 87 |
| 48 | Guidance on Platelet Transfusion for Patients With Hypoproliferative Thrombocytopenia | Transfusion Medicine Reviews | 2015 | 87 |
| 49 | The Mechanisms of Action of Intravenous Immunoglobulin and Polyclonal Anti-D Immunoglobulin in the Amelioration of Immune Thrombocytopenic Purpura: What Do We Really Know? | Transfusion Medicine Reviews | 2008 | 82 |
| 50 | A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg? | Blood | 2007 | 81 |
