# | Title | Journal | Year | Citations |
---|
1 | Nucleated Conformational Conversion and the Replication of Conformational Information by a Prion Determinant | Science | 2000 | 912 |
2 | Pleiotropic Effects of Statins on the Cardiovascular System | Circulation Research | 2017 | 808 |
3 | Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences | Cardiovascular Research | 2005 | 483 |
4 | Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer | FASEB Journal | 2012 | 458 |
5 | Pulmonary Arterial Hypertension | Journal of the American College of Cardiology | 2013 | 432 |
6 | Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation | European Respiratory Journal | 2010 | 427 |
7 | The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun | Nature Medicine | 2012 | 400 |
8 | Epigenetic Attenuation of Mitochondrial Superoxide Dismutase 2 in Pulmonary Arterial Hypertension | Circulation | 2010 | 361 |
9 | Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1α-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer | American Journal of Physiology - Heart and Circulatory Physiology | 2008 | 319 |
10 | Sustained hemodynamic effects of an infusion of nesiritide (human b-type natriuretic peptide) in heart failure | Journal of the American College of Cardiology | 1999 | 317 |
11 | Endothelial dihydrofolate reductase: Critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 311 |
12 | Dynamin‐related protein 1 (Drp1)‐mediated diastolic dysfunction in myocardial ischemia‐reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission | FASEB Journal | 2014 | 284 |
13 | Discordance Between Echocardiography and MRI in the Assessment of Mitral Regurgitation Severity | Journal of the American College of Cardiology | 2015 | 281 |
14 | Whole-genome association study identifies STK39 as a hypertension susceptibility gene | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 280 |
15 | The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle | Journal of Molecular Medicine | 2010 | 271 |
16 | γ-Sarcoglycan Deficiency Leads to Muscle Membrane Defects and Apoptosis Independent of Dystrophin | Journal of Cell Biology | 1998 | 269 |
17 | Atomic force microscopy and dissection of gap junctions | Science | 1991 | 256 |
18 | Filamin 2 (FLN2): A Muscle-specific Sarcoglycan Interacting Protein | Journal of Cell Biology | 2000 | 253 |
19 | Clinical Characteristics of Pulmonary Hypertension in Patients With Heart Failure and Preserved Ejection Fraction | Circulation: Heart Failure | 2011 | 253 |
20 | Differential diagnosis of cardiac masses using contrast echocardiographic perfusion imaging | Journal of the American College of Cardiology | 2004 | 249 |
21 | Usefulness of Red Cell Distribution Width as a Prognostic Marker in Pulmonary Hypertension††Conflicts of interest: Dr. Gomberg-Maitland has received research grant support from Actelion Pharmaceuticals Ltd., Allschwil, Switzerland; CoTherix, Inc., South San Francisco, California; Encysive Pharmaceuticals Inc., Houston, Texas; Gilead Sciences Inc., Foster City, California; Eli Lilly/ICOS, Indianapolis, Indiana; Pfizer Inc., New York, New York; and United Therapeutics, Silver Spring, Maryland. Dr. Gomberg-Mai | American Journal of Cardiology | 2009 | 229 |
22 | Utility of Nontraditional Risk Markers in Atherosclerotic Cardiovascular Disease Risk Assessment | Journal of the American College of Cardiology | 2016 | 226 |
23 | Nesprin-1α self-associates and binds directly to emerin and lamin A in vitro | FEBS Letters | 2002 | 218 |
24 | NAD(P)H Oxidase–Dependent Self-Propagation of Hydrogen Peroxide and Vascular Disease | Circulation Research | 2005 | 214 |
25 | Caveolin-3 in muscular dystrophy | Human Molecular Genetics | 1998 | 200 |
26 | Dominant negative myostatin produces hypertrophy without hyperplasia in muscle | FEBS Letters | 2000 | 193 |
27 | Phosphodiesterase Type 5 Inhibitors for Pulmonary Arterial Hypertension | New England Journal of Medicine | 2009 | 192 |
28 | Sudden Cardiac Death Risk Stratification in Patients With Nonischemic Dilated Cardiomyopathy | Journal of the American College of Cardiology | 2014 | 184 |
29 | PGC1α-mediated Mitofusin-2 Deficiency in Female Rats and Humans with Pulmonary Arterial Hypertension | American Journal of Respiratory and Critical Care Medicine | 2013 | 177 |
30 | Vascular endothelial dysfunction, a major mediator in diabetic cardiomyopathy | Acta Pharmacologica Sinica | 2019 | 174 |
31 | Latent TGF-β–binding protein 4 modifies muscular dystrophy in mice | Journal of Clinical Investigation | 2009 | 172 |
32 | Differential requirement for individual sarcoglycans and dystrophin in the assembly and function of the dystrophin-glycoprotein complex | Journal of Cell Science | 2000 | 168 |
33 | Lung 18F-Fluorodeoxyglucose Positron Emission Tomography for Diagnosis and Monitoring of Pulmonary Arterial Hypertension | American Journal of Respiratory and Critical Care Medicine | 2012 | 159 |
34 | A Central Role for CD68(+) Macrophages in Hepatopulmonary Syndrome | American Journal of Respiratory and Critical Care Medicine | 2011 | 158 |
35 | Utility of a Deep-Learning Algorithm to Guide Novices to Acquire Echocardiograms for Limited Diagnostic Use | JAMA Cardiology | 2021 | 158 |
36 | Clinical Implications of Determining BMPR2 Mutation Status in a Large Cohort of Children and Adults With Pulmonary Arterial Hypertension | Journal of Heart and Lung Transplantation | 2008 | 157 |
37 | Atrial Fibrillation After Radiofrequency Ablation of Type I Atrial Flutter | Circulation | 1998 | 151 |
38 | Netrin-1 induces angiogenesis via a DCC-dependent ERK1/2-eNOS feed-forward mechanism | Proceedings of the National Academy of Sciences of the United States of America | 2006 | 149 |
39 | Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension | Journal of Molecular Medicine | 2013 | 143 |
40 | Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2010 | 142 |
41 | Solid angle theory and the electrocardiogram: Physiologic and quantitative interpretations | Progress in Cardiovascular Diseases | 1977 | 139 |
42 | Muscle-Specific Promoters May Be Necessary for Adeno-Associated Virus-Mediated Gene Transfer in the Treatment of Muscular Dystrophies | Human Gene Therapy | 2001 | 138 |
43 | Myne-1, a spectrin repeat transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/C | Journal of Cell Science | 2002 | 138 |
44 | Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure | Journal of Molecular Medicine | 2010 | 137 |
45 | Relationship of the Pulmonary Artery End-Diastolic Pressure to the Left Ventricular End-Diastolic and Mean Filling Pressures in Patients With and Without Left Ventricular Dysfunction | Circulation | 1970 | 136 |
46 | Physiologic mechanisms governing hemodynamic responses to positive inotropic therapy in patients with dilated cardiomyopathy. | Circulation | 1988 | 135 |
47 | Empowering self-renewal and differentiation: the role of mitochondria in stem cells | Journal of Molecular Medicine | 2010 | 135 |
48 | The Nuclear Envelope Protein Emerin Binds Directly to Histone Deacetylase 3 (HDAC3) and Activates HDAC3 Activity | Journal of Biological Chemistry | 2012 | 134 |
49 | Epicardial–Myocardial Signaling Directing Coronary Vasculogenesis | Circulation Research | 2010 | 131 |
50 | Current practice for determining pulmonary capillary wedge pressure predisposes to serious errors in the classification of patients with pulmonary hypertension | American Heart Journal | 2012 | 130 |