| # | Title | Journal | Year | Citations |
|---|
| 1 | Increased plasma levels of interleukin-1, interleukin-6 and α-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain? | Journal of Neuroimmunology | 2000 | 379 |
| 2 | A Magnetization Transfer Imaging Study of Normal-Appearing White Matter in Multiple Sclerosis | Neurology | 1995 | 353 |
| 3 | Comparison of two dosing frequencies of subcutaneous interferon beta-1a in patients with a first clinical demyelinating event suggestive of multiple sclerosis (REFLEX): a phase 3 randomised controlled trial | Lancet Neurology, The | 2012 | 185 |
| 4 | The impact of bilingualism on brain reserve and metabolic connectivity in Alzheimer's dementia | Proceedings of the National Academy of Sciences of the United States of America | 2017 | 164 |
| 5 | Central vein sign differentiates Multiple Sclerosis from central nervous system inflammatory vasculopathies | Annals of Neurology | 2018 | 160 |
| 6 | Intra-observer reproducibility in measuring new putative MR markers of demyelination and axonal loss in multiple sclerosis: a comparison with conventional T2-weighted images | Journal of Neurology | 1997 | 153 |
| 7 | A randomised controlled trial of intravenous immunoglobulin in IgM paraprotein associated demyelinating neuropathy | Journal of Neurology | 2002 | 151 |
| 8 | Correlations between monthly enhanced MRI Lesion rate and changes in T2 Lesion volume in multiple sclerosis | Annals of Neurology | 1998 | 150 |
| 9 | Heterogeneity of autoantibodies in stiff-man syndrome | Annals of Neurology | 1993 | 121 |
| 10 | A spinal cord MRI study of benign and secondary progressive multiple sclerosis | Journal of Neurology | 1996 | 115 |
| 11 | Non-surgical treatments for the management of early osteoarthritis | Knee Surgery, Sports Traumatology, Arthroscopy | 2016 | 108 |
| 12 | Vitamin D levels and risk of multiple sclerosis in patients with clinically isolated syndromes | Multiple Sclerosis Journal | 2014 | 94 |
| 13 | Brain metabolic maps in Mild Cognitive Impairment predict heterogeneity of progression to dementia | NeuroImage: Clinical | 2015 | 94 |
| 14 | Axonal damage and loss of connectivity in nigrostriatal and mesolimbic dopamine pathways in early Parkinson's disease | NeuroImage: Clinical | 2017 | 89 |
| 15 | Efficacy and safety of cannabinoid oromucosal spray for multiple sclerosis spasticity | Journal of Neurology, Neurosurgery and Psychiatry | 2016 | 88 |
| 16 | Nocturnal Paroxysmal Arousals With Motor Behaviors During Sleep: Frontal Lobe Epilepsy or Parasomnia? | Journal of Clinical Neurophysiology | 1997 | 82 |
| 17 | Effect of training and different measurement strategies on the reproducibility of brain MRI lesion load measurements in multiple sclerosis | Neurology | 1998 | 80 |
| 18 | Interscanner variation in brain MRI lesion load measurements in MS: Implications for clinical trials | Neurology | 1997 | 77 |
| 19 | Mitoxantrone for multiple sclerosis | The Cochrane Library | 2013 | 75 |
| 20 | Comparison of triple dose versus standard dose gadolinium-DTPA for detection of MRI enhancing lesions in patients with primary progressive multiple sclerosis. | Journal of Neurology, Neurosurgery and Psychiatry | 1995 | 68 |
| 21 | Cross-validation of biomarkers for the early differential diagnosis and prognosis of dementia in a clinical setting | European Journal of Nuclear Medicine and Molecular Imaging | 2016 | 66 |
| 22 | Natalizumab versus fingolimod in patients with relapsing-remitting multiple sclerosis non-responding to first-line injectable therapies | Multiple Sclerosis Journal | 2016 | 62 |
| 23 | Brain magnetic resonance imaging and multimodal evoked potentials in benign and secondary progressive multiple sclerosis. | Journal of Neurology, Neurosurgery and Psychiatry | 1995 | 61 |
| 24 | Interferon-γ and interferon-β affect endogenous catecholamines in human peripheral blood mononuclear cells: Implications for multiple sclerosis | Journal of Neuroimmunology | 2005 | 58 |
| 25 | Metabolic connectomics targeting brain pathology in dementia with Lewy bodies | Journal of Cerebral Blood Flow and Metabolism | 2017 | 57 |
| 26 | Neuropsychiatric subsyndromes and brain metabolic network dysfunctions in early onset Alzheimer's disease | Human Brain Mapping | 2016 | 55 |
| 27 | The Role of Single-Subject Brain Metabolic Patterns in the Early Differential Diagnosis of Primary Progressive Aphasias and in Prediction of Progression to Dementia | Journal of Alzheimer's Disease | 2016 | 54 |
| 28 | Predictors of punding in Parkinson's disease: Results from a questionnaire survey | Movement Disorders | 2007 | 53 |
| 29 | Circadian Variation of the Effects of Immobility on Symptoms of Restless Legs Syndrome | Sleep | 2005 | 52 |
| 30 | Dural sinus thrombosis in spontaneous intracranial hypotension | Journal of Neurology | 2006 | 51 |
| 31 | Riboflavin and migraine: the bridge over troubled mitochondria | Neurological Sciences | 2014 | 50 |
| 32 | Heart rate variability during acute psychosocial stress: A randomized cross-over trial of verbal and non-verbal laboratory stressors | International Journal of Psychophysiology | 2018 | 47 |
| 33 | Efficacy of Cladribine Tablets in high disease activity subgroups of patients with relapsing multiple sclerosis: A post hoc analysis of the CLARITY study | Multiple Sclerosis Journal | 2019 | 46 |
| 34 | Influence of Clinical Variables on Neuropsychological Performance in Multiple Sclerosis | European Neurology | 1994 | 45 |
| 35 | Retrospective study of a large population of patients affected with mitochondrial disorders: clinical, morphological and molecular genetic evaluation | Journal of Neurology | 2001 | 45 |
| 36 | Efficacy of fingolimod and interferon beta-1b on cognitive, MRI, and clinical outcomes in relapsing–remitting multiple sclerosis: an 18-month, open-label, rater-blinded, randomised, multicentre study (the GOLDEN study) | Journal of Neurology | 2017 | 44 |
| 37 | The effect of imprecise repositioning on lesion volume measurements in patients with multiple sclerosis | Neurology | 1997 | 43 |
| 38 | Intravenous thrombolysis or endovascular therapy for acute ischemic stroke associated with cervical internal carotid artery occlusion: the ICARO-3 study | Journal of Neurology | 2015 | 43 |
| 39 | Triple dose of gadolinium-DTPA and delayed MRI in patients with benign multiple sclerosis. | Journal of Neurology, Neurosurgery and Psychiatry | 1996 | 42 |
| 40 | Recurrent disease-activity rebound in a patient with multiple sclerosis after natalizumab discontinuations for pregnancy planning | Multiple Sclerosis Journal | 2016 | 41 |
| 41 | Evaluation of an optimized [18F]fluoro‐deoxy‐glucose positron emission tomography voxel‐wise method to early support differential diagnosis in atypical Parkinsonian disorders | European Journal of Neurology | 2017 | 40 |
| 42 | Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4) | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 39 |
| 43 | Islet Transplantation Stabilizes Hemostatic Abnormalities and Cerebral Metabolism in Individuals With Type 1 Diabetes | Diabetes Care | 2014 | 39 |
| 44 | Long-term follow-up of pediatric MS patients starting treatment with injectable first-line agents: A multicentre, Italian, retrospective, observational study | Multiple Sclerosis Journal | 2019 | 38 |
| 45 | Training in the practice of noninvasive brain stimulation: Recommendations from an IFCN committee | Clinical Neurophysiology | 2021 | 38 |
| 46 | Serum neurofilaments increase at progressive multifocal leukoencephalopathy onset in natalizumab‐treated multiple sclerosis patients | Annals of Neurology | 2019 | 30 |
| 47 | Dizziness, migrainous vertigo and psychiatric disorders | Journal of Laryngology and Otology | 2010 | 29 |
| 48 | Smart watch, smarter EDSS: Improving disability assessment in multiple sclerosis clinical practice | Journal of the Neurological Sciences | 2017 | 29 |
| 49 | Walking-related digital mobility outcomes as clinical trial endpoint measures: protocol for a scoping review | BMJ Open | 2020 | 29 |
| 50 | Brain Stem Magnetic Resonance Imaging and Evoked Potential Studies of Symptomatic Multiple Sclerosis Patients | European Neurology | 1993 | 27 |
