| # | Title | Journal | Year | Citations |
|---|
| 1 | Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2019 | 866 |
| 2 | Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span | Journal of Experimental Medicine | 2017 | 755 |
| 3 | Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study | Lancet Respiratory Medicine,the | 2013 | 486 |
| 4 | Role of Oxidants in NF-κB Activation and TNF-α Gene Transcription Induced by Hypoxia and Endotoxin | Journal of Immunology | 2000 | 472 |
| 5 | Daily interruption of sedative infusions and complications of critical illness in mechanically ventilated patients* | Critical Care Medicine | 2004 | 423 |
| 6 | Churg-Strauss syndrome | Lancet, The | 2003 | 390 |
| 7 | Sepsis associated acute kidney injury | BMJ: British Medical Journal | 2019 | 380 |
| 8 | Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases | JAMA Oncology | 2017 | 376 |
| 9 | Phosphorylation of β-Catenin by Cyclic AMP-dependent Protein Kinase* | Journal of Biological Chemistry | 2006 | 373 |
| 10 | Particulate Matter Air Pollution: Effects on the Cardiovascular System | Frontiers in Endocrinology | 2018 | 358 |
| 11 | Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation | Nature Communications | 2013 | 328 |
| 12 | Acute Asthma in Adults | Chest | 2004 | 264 |
| 13 | TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2015 | 257 |
| 14 | Prostaglandins PGE2 and PGI2 promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation | Experimental Cell Research | 2007 | 251 |
| 15 | Peripheral Blood Mononuclear Cell Gene Expression Profiles Predict Poor Outcome in Idiopathic Pulmonary Fibrosis | Science Translational Medicine | 2013 | 242 |
| 16 | ERM-Dependent Movement of CD43 Defines a Novel Protein Complex Distal to the Immunological Synapse | Immunity | 2001 | 239 |
| 17 | Autoimmune-Featured Interstitial Lung Disease | Chest | 2011 | 236 |
| 18 | Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study | Lancet Respiratory Medicine,the | 2017 | 233 |
| 19 | Sensory neuropeptides and airway function | Journal of Applied Physiology | 1991 | 230 |
| 20 | Pathological supply dependence of O2 uptake during bacteremia in dogs | Journal of Applied Physiology | 1987 | 225 |
| 21 | PD-1 up-regulation on CD4 + T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production | Science Translational Medicine | 2018 | 225 |
| 22 | Blockade of Inflammation and Airway Hyperresponsiveness in Immune-sensitized Mice by Dominant-Negative Phosphoinositide 3-Kinase–TAT | Journal of Experimental Medicine | 2003 | 219 |
| 23 | Characterisation of patients with interstitial pneumonia with autoimmune features | European Respiratory Journal | 2016 | 219 |
| 24 | Effects of surface tension and viscosity on airway reopening | Journal of Applied Physiology | 1990 | 190 |
| 25 | Bronchiectasis | Nature Reviews Disease Primers | 2018 | 181 |
| 26 | Inhalational exposure to particulate matter air pollution alters the composition of the gut microbiome | Environmental Pollution | 2018 | 181 |
| 27 | The Association Between Depression, Lung Function, and Health-Related Quality of Life Among Adults With Cystic Fibrosis | Chest | 2007 | 163 |
| 28 | Heliox improves pulsus paradoxus and peak expiratory flow in nonintubated patients with severe asthma. | American Journal of Respiratory and Critical Care Medicine | 1995 | 158 |
| 29 | Basic Fibroblast Growth Factor Stimulates Matrix Metalloproteinase-13 via the Molecular Cross-talk between the Mitogen-activated Protein Kinases and Protein Kinase Cδ Pathways in Human Adult Articular Chondrocytes | Journal of Biological Chemistry | 2007 | 156 |
| 30 | Redox Regulation of 4-Hydroxy-2-nonenal-mediated Endothelial Barrier Dysfunction by Focal Adhesion, Adherens, and Tight Junction Proteins | Journal of Biological Chemistry | 2006 | 152 |
| 31 | Sleep Apnea and Cancer: Analysis of a Nationwide Population Sample | Sleep | 2016 | 152 |
| 32 | The Diagnosis and Management of Alpha-1 Antitrypsin Deficiency in the Adult | Chronic Obstructive Pulmonary Diseases (Miami, Fla ) | 2016 | 148 |
| 33 | Acute respiratory acidosis decreases left ventricular contractility but increases cardiac output in dogs. | Circulation Research | 1990 | 147 |
| 34 | Categorization and impact of pulmonary hypertension in patients with advanced COPD | Respiratory Medicine | 2010 | 147 |
| 35 | Determinants of Hypercapnia in Obese Patients With Obstructive Sleep Apnea | Chest | 2009 | 145 |
| 36 | A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle | Journal of Allergy and Clinical Immunology | 2018 | 143 |
| 37 | Microbes Are Associated with Host Innate Immune Response in Idiopathic Pulmonary Fibrosis | American Journal of Respiratory and Critical Care Medicine | 2017 | 130 |
| 38 | NOX Enzymes and Pulmonary Disease | Antioxidants and Redox Signaling | 2009 | 129 |
| 39 | The effect of sex and age on the comorbidity burden of OSA: an observational analysis from a large nationwide US health claims database | European Respiratory Journal | 2016 | 129 |
| 40 | Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways | Journal of Allergy and Clinical Immunology | 2016 | 128 |
| 41 | Epac/Rap and PKA are novel mechanisms of ANP‐induced Rac‐mediated pulmonary endothelial barrier protection | Journal of Cellular Physiology | 2008 | 127 |
| 42 | IL-6 Inhibition in Critically Ill COVID-19 Patients Is Associated With Increased Secondary Infections | Frontiers in Medicine | 2020 | 125 |
| 43 | COPD Readmissions | Chest | 2016 | 124 |
| 44 | Allergic Bronchopulmonary Aspergillosis | Proceedings of the American Thoracic Society | 2010 | 122 |
| 45 | Intracellular Generation of Sphingosine 1-Phosphate in Human Lung Endothelial Cells | Journal of Biological Chemistry | 2007 | 120 |
| 46 | HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium | ELife | 2017 | 120 |
| 47 | HGF attenuates thrombin‐induced endothelial permeability by Tiaml‐mediated activation of the Rac pathway and by Tiam1/Rac‐dependent inhibition of the Rho pathway | FASEB Journal | 2007 | 119 |
| 48 | Interstitial pneumonia with autoimmune features: Clinical, radiologic, and histological characteristics and outcome in a series of 57 patients | Respiratory Medicine | 2017 | 119 |
| 49 | Divergent differentiation paths in airway smooth muscle culture: induction of functionally contractile myocytes | American Journal of Physiology - Lung Cellular and Molecular Physiology | 1999 | 117 |
| 50 | Daily sedative interruption in mechanically ventilated patients at risk for coronary artery disease* | Critical Care Medicine | 2007 | 116 |
