| # | Title | Journal | Year | Citations |
|---|
| 1 | Adalimumab for Maintenance of Clinical Response and Remission in Patients With Crohn’s Disease: The CHARM Trial | Gastroenterology | 2007 | 1,986 |
| 2 | Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10−/− mice | Nature | 2012 | 1,506 |
| 3 | Antitumor Necrosis Factor Therapy for Inflammatory Bowel Disease: A Review of Agents, Pharmacology, Clinical Results, and Safety | Inflammatory Bowel Diseases | 1999 | 356 |
| 4 | Differentiation-Dependent Expression of the Brown Adipocyte Uncoupling Protein Gene: Regulation by Peroxisome Proliferator-Activated Receptor γ | Molecular and Cellular Biology | 1996 | 268 |
| 5 | Intentional infliximab use during pregnancy for induction or maintenance of remission in Crohn's disease | Alimentary Pharmacology and Therapeutics | 2005 | 262 |
| 6 | Systematic review: adherence issues in the treatment of ulcerative colitis | Alimentary Pharmacology and Therapeutics | 2006 | 261 |
| 7 | Identification of microRNAs associated with ileal and colonic Crohnʼs disease† | Inflammatory Bowel Diseases | 2010 | 253 |
| 8 | A Controlled Trial of Azathioprine in the Management of Chronic Ulcerative Colitis | Gastroenterology | 1975 | 222 |
| 9 | Impaired Folic Acid Absorption in Inflammatory Bowel Disease: Effects of Salicylazosulfapyridine (Azulfidine) | Gastroenterology | 1973 | 208 |
| 10 | Na+/H+ exchangers, NHE-1 and NHE-3, of rat intestine. Expression and localization. | Journal of Clinical Investigation | 1994 | 202 |
| 11 | Peripheral blood MicroRNAs distinguish active ulcerative colitis and Crohnʼs disease | Inflammatory Bowel Diseases | 2011 | 198 |
| 12 | Racial Disparity in Gastrointestinal Cancer Risk | Gastroenterology | 2017 | 194 |
| 13 | Vitamin D Deficiency and Bone Disease in Patients With Crohn's Disease | Gastroenterology | 1982 | 193 |
| 14 | A controlled trial of azathioprine in Crohn's disease | The American Journal of Digestive Diseases | 1975 | 191 |
| 15 | Complete response of metastatic melanoma in a patient with Crohn’s disease simultaneously receiving anti-α4β7 and anti-PD1 antibodies | | 2019 | 143 |
| 16 | Dynamic migration of γδ intraepithelial lymphocytes requires occludin | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 142 |
| 17 | Bacterial community structure and functional contributions to emergence of health or necrotizing enterocolitis in preterm infants | Microbiome | 2013 | 138 |
| 18 | Activation of the Nuclear Receptor Peroxisome Proliferator-activated Receptor γ Promotes Brown Adipocyte Differentiation | Journal of Biological Chemistry | 1996 | 135 |
| 19 | Interventions to Improve Care Related to Colorectal Cancer Among Racial and Ethnic Minorities: A Systematic Review | Journal of General Internal Medicine | 2012 | 130 |
| 20 | The Cost of Hospitalization in Crohn's Disease | American Journal of Gastroenterology | 2000 | 128 |
| 21 | Growth retardation in inflammatory bowel disease | Gastroenterology | 1978 | 127 |
| 22 | MicroRNAs in inflammatory bowel disease | Inflammatory Bowel Diseases | 2012 | 121 |
| 23 | LFA-1 on CD4+ T Cells Is Required for Optimal Antigen-Dependent Activation In Vivo | Journal of Immunology | 2004 | 99 |
| 24 | Erythropoietin Protects Intestinal Epithelial Barrier Function and Lowers the Incidence of Experimental Neonatal Necrotizing Enterocolitis | Journal of Biological Chemistry | 2011 | 98 |
| 25 | Functional consequences of NOD2 (CARD15) mutations | Inflammatory Bowel Diseases | 2006 | 96 |
| 26 | Comparison of brush and biopsy sampling methods of the ileal pouch for assessment of mucosa-associated microbiota of human subjects | Microbiome | 2014 | 95 |
| 27 | NOD2 Expression is Regulated by microRNAs in Colonic Epithelial HCT116 Cells | Inflammatory Bowel Diseases | 2014 | 90 |
| 28 | Polymicrobial Sepsis Following Endoscopic Retrograde Cholangiopancreatography | Gastroenterology | 1975 | 82 |
| 29 | Genetic and Metabolic Signals during Acute Enteric Bacterial Infection Alter the Microbiota and Drive Progression to Chronic Inflammatory Disease | Cell Host and Microbe | 2016 | 81 |
| 30 | Antitumor necrosis factor therapy for inflammatory bowel disease: A review of agents, pharmacology, clinical results, and safety | Inflammatory Bowel Diseases | 0 | 81 |
| 31 | Tissue distribution of Na+/H+exchanger isoforms NHE2 and NHE4 in rat intestine and kidney | American Journal of Physiology - Cell Physiology | 1997 | 80 |
| 32 | Metformin for primary colorectal cancer prevention in patients with diabetes: A case‐control study in a US population | Cancer | 2015 | 80 |
| 33 | The antioxidant (−)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression | Biochemical Journal | 2002 | 79 |
| 34 | Enteral stent placement by double balloon enteroscopy for palliation of malignant small bowel obstruction | Gastrointestinal Endoscopy | 2006 | 77 |
| 35 | Nutritional modulation of gut microbiota — the impact on metabolic disease pathophysiology | Journal of Nutritional Biochemistry | 2016 | 77 |
| 36 | Manometric asymmetry of the lower-esophageal high-pressure zone | The American Journal of Digestive Diseases | 1977 | 72 |
| 37 | A Lupus-like Syndrome Associated With Infliximab Therapy | Inflammatory Bowel Diseases | 2003 | 71 |
| 38 | Inflammatory breast cancer (IBC): clues for targeted therapies | Breast Cancer Research and Treatment | 2013 | 71 |
| 39 | Fecal bacteriotherapy for ulcerative colitis: Patients are ready, are we? | Inflammatory Bowel Diseases | 2012 | 69 |
| 40 | The transcription factor Foxm1 is essential for the quiescence and maintenance of hematopoietic stem cells | Nature Immunology | 2015 | 68 |
| 41 | Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans | Gastroenterology | 2015 | 65 |
| 42 | miR-106b Fine Tunes ATG16L1 Expression and Autophagic Activity in Intestinal Epithelial HCT116 Cells | Inflammatory Bowel Diseases | 2013 | 64 |
| 43 | Innovative Health Care Disparities Curriculum for Incoming Medical Students | Journal of General Internal Medicine | 2008 | 63 |
| 44 | Inactivation of the vitamin D receptor in APCmin/+ mice reveals a critical role for the vitamin D receptor in intestinal tumor growth | International Journal of Cancer | 2012 | 63 |
| 45 | Human autophagy geneATG16L1is post-transcriptionally regulated byMIR142-3p | Autophagy | 2014 | 63 |
| 46 | Matrilysin-1 (MMP7) cleaves galectin-3 and inhibits wound healing in intestinal epithelial cells | Inflammatory Bowel Diseases | 2011 | 62 |
| 47 | A risk score to predict the development of hepatic encephalopathy in a population‐based cohort of patients with cirrhosis | Hepatology | 2018 | 60 |
| 48 | Fulminant Hepatic Failure from Heat Stroke Requiring Liver Transplantation | Journal of Clinical Gastroenterology | 2000 | 59 |
| 49 | Intestinal Calcium Absorption and Vitamin D Status in Chronic Cholestatic Liver Disease | Hepatology | 1984 | 57 |
| 50 | Aminosalicylates in inflammatory bowel disease | Alimentary Pharmacology and Therapeutics | 2004 | 52 |
