| # | Title | Journal | Year | Citations |
|---|
| 1 | Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats | Journal of Cerebral Blood Flow and Metabolism | 2013 | 782 |
| 2 | Exosome-Mediated Transfer of miR-133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth | Stem Cells | 2012 | 743 |
| 3 | The Impact of a Neuro-Intensivist on Patients with Stroke Admitted to a Neurosciences Intensive Care Unit | Neurocritical Care | 2008 | 642 |
| 4 | Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth | Cancer Letters | 2013 | 597 |
| 5 | MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles | Stem Cells | 2013 | 596 |
| 6 | Treatment of neural injury with marrow stromal cells | Lancet Neurology, The | 2002 | 576 |
| 7 | Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic | Lancet Neurology, The | 2009 | 536 |
| 8 | Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke | Progress in Neurobiology | 2016 | 434 |
| 9 | The cost of Alzheimer's disease in China and re‐estimation of costs worldwide | Alzheimer's and Dementia | 2018 | 404 |
| 10 | Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis | Nature Neuroscience | 2014 | 398 |
| 11 | American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2021 Version | Journal of Clinical Neurophysiology | 2021 | 370 |
| 12 | A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia | Journal of Neuroscience Methods | 2002 | 356 |
| 13 | Exosomes — beyond stem cells for restorative therapy in stroke and neurological injury | Nature Reviews Neurology | 2019 | 353 |
| 14 | Postischemic administration of an anti-Mac-1 antibody reduces ischemic cell damage after transient middle cerebral artery occlusion in rats. | Stroke | 1994 | 333 |
| 15 | Adenosine A2A receptor antagonist istradefylline (KW‐6002) reduces “off” time in Parkinson's disease: A double‐blind, randomized, multicenter clinical trial (6002‐US‐005) | Annals of Neurology | 2008 | 333 |
| 16 | Therapeutic Benefit of Bone Marrow Stromal Cells Administered 1 Month after Stroke | Journal of Cerebral Blood Flow and Metabolism | 2007 | 326 |
| 17 | MR Imaging of Human Brain at 3.0 T: Preliminary Report on Transverse Relaxation Rates and Relation to Estimated Iron Content | Radiology | 1999 | 325 |
| 18 | Assessment of relative brain iron concentrations usingT2-weighted andT2*-weighted MRI at 3 Tesla | Magnetic Resonance in Medicine | 1994 | 317 |
| 19 | Temporal profile of ischemic tissue damage, neutrophil response, and vascular plugging following permanent and transient (2H) middle cerebral artery occlusion in the rat | Journal of the Neurological Sciences | 1994 | 304 |
| 20 | A management algorithm for patients with intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC) | Intensive Care Medicine | 2019 | 292 |
| 21 | Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury | Neurochemistry International | 2017 | 290 |
| 22 | The Effect of Hypothermia on Transient Middle Cerebral Artery Occlusion in the Rat | Journal of Cerebral Blood Flow and Metabolism | 1992 | 269 |
| 23 | Levodopa for the Treatment of Parkinson's Disease | New England Journal of Medicine | 2008 | 256 |
| 24 | Lower motor neuron syndromes defined by patterns of weakness, nerve conduction abnormalities, and high titers of antiglycolipid antibodies | Annals of Neurology | 1990 | 255 |
| 25 | Quantitative proton MR spectroscopic imaging of the human brain | Magnetic Resonance in Medicine | 1996 | 254 |
| 26 | Magnetic resonance imaging assessment of evolving focal cerebral ischemia. Comparison with histopathology in rats. | Stroke | 1994 | 253 |
| 27 | Exosomes/miRNAs as mediating cell-based therapy of stroke | Frontiers in Cellular Neuroscience | 2014 | 250 |
| 28 | Transient hyperthermia protects against subsequent forebrain ischemic cell damage in the rat | Neurology | 1989 | 248 |
| 29 | The Concept of Migraine as a State of Central Neuronal Hyperexcitability | Neurologic Clinics | 1990 | 246 |
| 30 | Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas | Nature Genetics | 2014 | 242 |
| 31 | Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat | Annals of Neurology | 1994 | 229 |
| 32 | Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons | Molecular Neurobiology | 2017 | 228 |
| 33 | Interregional variation of longitudinal relaxation rates in human brain at 3.0 T: Relation to estimated iron and water contents | Magnetic Resonance in Medicine | 2001 | 222 |
| 34 | Marrow Stromal Cell Transplantation after Traumatic Brain Injury Promotes Cellular Proliferation within the Brain | Neurosurgery | 2004 | 218 |
| 35 | Coherence a measure of the brain networks: past and present | Neuropsychiatric Electrophysiology | 2016 | 218 |
| 36 | Ischemic neurons recruit natural killer cells that accelerate brain infarction | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 216 |
| 37 | MicroRNA‐21 protects neurons from ischemic death | FEBS Journal | 2010 | 213 |
| 38 | Secondary Release of Exosomes from Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery after Stroke in Rats Treated with Exosomes Harvested from MicroRNA 133b-Overexpressing Multipotent Mesenchymal Stromal Cells | Cell Transplantation | 2017 | 210 |
| 39 | Single-voxel proton MRS of the human brain at 1.5T and 3.0T | Magnetic Resonance in Medicine | 2001 | 209 |
| 40 | Downregulation of Wnt2 and β-catenin by siRNA suppresses malignant glioma cell growth | Cancer Gene Therapy | 2009 | 209 |
| 41 | One-Year Follow-Up After Bone Marrow Stromal Cell Treatment in Middle-Aged Female Rats With Stroke | Stroke | 2007 | 198 |
| 42 | Temporal evolution of ischemic damage in rat brain measured by proton nuclear magnetic resonance imaging. | Stroke | 1991 | 195 |
| 43 | MicroRNA Profiling in Subventricular Zone after Stroke: MiR-124a Regulates Proliferation of Neural Progenitor Cells through Notch Signaling Pathway | PLoS ONE | 2011 | 193 |
| 44 | Nonlinear Regularization for Per Voxel Estimation of Magnetic Susceptibility Distributions From MRI Field Maps | IEEE Transactions on Medical Imaging | 2010 | 192 |
| 45 | Preliminary observations on brain energy metabolism in migraine studied by in vivo phosphorus 31 NMR spectroscopy | Neurology | 1989 | 189 |
| 46 | Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats. | Stroke | 1993 | 187 |
| 47 | Correlations between Magnetic Resonance Spectroscopy and Image-guided Histopathology, with Special Attention to Radiation Necrosis | Neurosurgery | 2002 | 180 |
| 48 | The fallacy of the lacune hypothesis. | Stroke | 1990 | 177 |
| 49 | Mild hypothermic intervention after graded ischemic stress in rats. | Stroke | 1991 | 176 |
| 50 | Low Brain Magnesium in Migraine | Headache | 1989 | 175 |
