| # | Title | Journal | Year | Citations |
|---|
| 1 | Birth Prevalence of Congenital Heart Disease Worldwide | Journal of the American College of Cardiology | 2011 | 2,400 |
| 2 | A newly discovered human pneumovirus isolated from young children with respiratory tract disease | Nature Medicine | 2001 | 1,821 |
| 3 | Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis | Nature Genetics | 2015 | 529 |
| 4 | A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations | Nature Genetics | 2014 | 497 |
| 5 | The Generation R Study: design and cohort update 2012 | European Journal of Epidemiology | 2012 | 486 |
| 6 | The Natural Course of Infantile Pompe's Disease: 20 Original Cases Compared With 133 Cases From the Literature | Pediatrics | 2003 | 463 |
| 7 | Titrating Steroids on Exhaled Nitric Oxide in Children with Asthma | American Journal of Respiratory and Critical Care Medicine | 2005 | 330 |
| 8 | International consensus on (ICON) pediatric asthma | Allergy: European Journal of Allergy and Clinical Immunology | 2012 | 327 |
| 9 | Air Pollution Exposure and Lung Function in Children: The ESCAPE Project | Environmental Health Perspectives | 2013 | 320 |
| 10 | Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis | Nature Genetics | 2012 | 311 |
| 11 | Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care Medicine | Intensive Care Medicine | 2018 | 305 |
| 12 | Dutch national survey to test the STRONGkids nutritional risk screening tool in hospitalized children | Clinical Nutrition | 2010 | 292 |
| 13 | Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion | Journal of Experimental Medicine | 2007 | 279 |
| 14 | Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: A randomized, double-blinded, placebo-controlled, dose-finding study | Critical Care Medicine | 2003 | 265 |
| 15 | Intervention strategies to improve nutrition and health behaviours before conception | Lancet, The | 2018 | 254 |
| 16 | Genetics, Clinical Features, and Long-Term Outcome of Noncompaction Cardiomyopathy | Journal of the American College of Cardiology | 2018 | 242 |
| 17 | Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials | Lancet Diabetes and Endocrinology,the | 2020 | 235 |
| 18 | Air Pollution and Respiratory Infections during Early Childhood: An Analysis of 10 European Birth Cohorts within the ESCAPE Project | Environmental Health Perspectives | 2014 | 224 |
| 19 | Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight | Nature Genetics | 2010 | 223 |
| 20 | Malnutrition in critically ill children: from admission to 6 months after discharge | Clinical Nutrition | 2004 | 220 |
| 21 | Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns | Nature Communications | 2016 | 219 |
| 22 | Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium | Human Molecular Genetics | 2017 | 211 |
| 23 | Serum Anti-Müllerian Hormone Levels in Healthy Females: A Nomogram Ranging from Infancy to Adulthood | Journal of Clinical Endocrinology and Metabolism | 2012 | 203 |
| 24 | Dietary Inflammatory Index and Non-Communicable Disease Risk: A Narrative Review | Nutrients | 2019 | 198 |
| 25 | Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity | Human Molecular Genetics | 2013 | 188 |
| 26 | Risk factors for necrotizing enterocolitis in neonates: a systematic review of prognostic studies | BMC Pediatrics | 2017 | 186 |
| 27 | Low socioeconomic status is a risk factor for preeclampsia: the Generation R Study | Journal of Hypertension | 2008 | 171 |
| 28 | Maternal Smoking and Fetal Growth Characteristics in Different Periods of Pregnancy: The Generation R Study | American Journal of Epidemiology | 2007 | 166 |
| 29 | Early growth characteristics and the risk of reduced lung function and asthma: A meta-analysis of 25,000 children | Journal of Allergy and Clinical Immunology | 2016 | 154 |
| 30 | Culture-Negative Early-Onset Neonatal Sepsis — At the Crossroad Between Efficient Sepsis Care and Antimicrobial Stewardship | Frontiers in Pediatrics | 2018 | 151 |
| 31 | Meta-analysis identifies seven susceptibility loci involved in the atopic march | Nature Communications | 2015 | 148 |
| 32 | The effect of cumulative energy and protein deficiency on anthropometric parameters in a pediatric ICU population | Clinical Nutrition | 2004 | 142 |
| 33 | The microcirculation: a key player in obesity-associated cardiovascular disease | Cardiovascular Research | 2017 | 141 |
| 34 | Peak bone mineral density, lean body mass and fractures | Bone | 2010 | 140 |
| 35 | Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight | Nature Communications | 2019 | 140 |
| 36 | Placebo-controlled Trial of House Dust Mite–impermeable Mattress Covers | American Journal of Respiratory and Critical Care Medicine | 2002 | 138 |
| 37 | Toward an operative diagnosis of fussy/picky eating: a latent profile approach in a population-based cohort | International Journal of Behavioral Nutrition and Physical Activity | 2014 | 137 |
| 38 | Splitting hair for cortisol? Associations of socio-economic status, ethnicity, hair color, gender and other child characteristics with hair cortisol and cortisone | Psychoneuroendocrinology | 2016 | 135 |
| 39 | Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells | Proceedings of the National Academy of Sciences of the United States of America | 2016 | 135 |
| 40 | Right and left ventricular function after chronic pulmonary artery banding in rats assessed with biventricular pressure-volume loops | American Journal of Physiology - Heart and Circulatory Physiology | 2006 | 134 |
| 41 | Withdrawal symptoms in children after long-term administration of sedatives and/or analgesics: a literature review. “Assessment remains troublesome” | Intensive Care Medicine | 2007 | 134 |
| 42 | Socioeconomic status in children is associated with hair cortisol levels as a biological measure of chronic stress | Psychoneuroendocrinology | 2016 | 131 |
| 43 | Population pharmacokinetics and metabolism of midazolam in pediatric intensive care patients | Critical Care Medicine | 2003 | 130 |
| 44 | Fetal Growth and Prenatal Exposure to Bisphenol A: The Generation R Study | Environmental Health Perspectives | 2013 | 130 |
| 45 | Minimal residual disease levels in bone marrow and peripheral blood are comparable in children with T cell acute lymphoblastic leukemia (ALL), but not in precursor-B-ALL | Leukemia | 2002 | 129 |
| 46 | Vancomycin | Clinical Pharmacokinetics | 2004 | 128 |
| 47 | Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure | Allergy: European Journal of Allergy and Clinical Immunology | 2009 | 127 |
| 48 | Children Born Small for Gestational Age: Differential Diagnosis, Molecular Genetic Evaluation, and Implications | Endocrine Reviews | 2018 | 122 |
| 49 | The Mediterranean diet and fetal size parameters: the Generation R Study | British Journal of Nutrition | 2012 | 120 |
| 50 | Reduced insulin sensitivity and the presence of cardiovascular risk factors in short prepubertal children born small for gestational age (SGA) | Clinical Endocrinology | 2005 | 119 |
