| # | Title | Journal | Year | Citations |
|---|
| 1 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 2 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 4 | Common genetic determinants of vitamin D insufficiency: a genome-wide association study | Lancet, The | 2010 | 1,385 |
| 5 | Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement | Thyroid | 2014 | 1,283 |
| 6 | Genome-wide association study of blood pressure and hypertension | Nature Genetics | 2009 | 1,224 |
| 7 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 8 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
| 9 | ENETS Consensus Guidelines Update for the Management of Patients with Functional Pancreatic Neuroendocrine Tumors and Non-Functional Pancreatic Neuroendocrine Tumors | Neuroendocrinology | 2016 | 1,074 |
| 10 | Cushing's syndrome | Lancet, The | 2015 | 988 |
| 11 | Large-scale genotyping identifies 41 new loci associated with breast cancer risk | Nature Genetics | 2013 | 960 |
| 12 | Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility | Nature Genetics | 2014 | 959 |
| 13 | A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance | Nature Genetics | 2012 | 762 |
| 14 | DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis | American Journal of Human Genetics | 2016 | 717 |
| 15 | Homocysteine Levels and the Risk of Osteoporotic Fracture | New England Journal of Medicine | 2004 | 673 |
| 16 | Variants in MTNR1B influence fasting glucose levels | Nature Genetics | 2009 | 662 |
| 17 | 2013 ETA Guideline: Management of Subclinical Hypothyroidism | European Thyroid Journal | 2013 | 623 |
| 18 | Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation | Lancet, The | 2004 | 615 |
| 19 | An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans | Diabetes | 2017 | 615 |
| 20 | Identification of Monocarboxylate Transporter 8 as a Specific Thyroid Hormone Transporter | Journal of Biological Chemistry | 2003 | 602 |
| 21 | Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge | Nature Genetics | 2010 | 591 |
| 22 | Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression | Nature Genetics | 2021 | 590 |
| 23 | Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus | Clinical Pharmacology and Therapeutics | 2003 | 580 |
| 24 | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture | Nature Genetics | 2013 | 578 |
| 25 | An atlas of genetic influences on osteoporosis in humans and mice | Nature Genetics | 2019 | 557 |
| 26 | Multiple loci associated with indices of renal function and chronic kidney disease | Nature Genetics | 2009 | 553 |
| 27 | A catalog of genetic loci associated with kidney function from analyses of a million individuals | Nature Genetics | 2019 | 549 |
| 28 | Hair cortisol, stress exposure, and mental health in humans: A systematic review | Psychoneuroendocrinology | 2013 | 548 |
| 29 | Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche | Nature | 2014 | 548 |
| 30 | Rare and low-frequency coding variants alter human adult height | Nature | 2017 | 544 |
| 31 | Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine | Nature Genetics | 2016 | 520 |
| 32 | Hypertension | Circulation Research | 2015 | 517 |
| 33 | Consensus report on the use of somatostatin analogs for the management of neuroendocrine tumors of the gastroenteropancreatic system | Annals of Oncology | 2004 | 486 |
| 34 | The Generation R Study: design and cohort update 2012 | European Journal of Epidemiology | 2012 | 486 |
| 35 | High Serum Uric Acid as a Novel Risk Factor for Type 2 Diabetes | Diabetes Care | 2008 | 484 |
| 36 | Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture | Nature | 2015 | 483 |
| 37 | An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis | Lancet Oncology, The | 2009 | 477 |
| 38 | EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis | Allergy: European Journal of Allergy and Clinical Immunology | 2018 | 473 |
| 39 | Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution | PLoS Genetics | 2009 | 453 |
| 40 | Prevention of Catheter-Related Bacteremia with a Daily Ethanol Lock in Patients with Tunnelled Catheters: A Randomized, Placebo-Controlled Trial | PLoS ONE | 2010 | 429 |
| 41 | Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk | Nature Genetics | 2017 | 426 |
| 42 | Guidelines for the Diagnosis and Treatment of Neuroendocrine Gastrointestinal Tumours | Neuroendocrinology | 2004 | 422 |
| 43 | Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function | Nature Communications | 2016 | 412 |
| 44 | Renin-Angiotensin System Blockers and the COVID-19 Pandemic | Hypertension | 2020 | 412 |
| 45 | Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure | Nature Genetics | 2011 | 403 |
| 46 | Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia | Nature Genetics | 2013 | 398 |
| 47 | Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis | Nature Genetics | 2017 | 391 |
| 48 | Clinical Genetic Testing for Familial Hypercholesterolemia | Journal of the American College of Cardiology | 2018 | 387 |
| 49 | Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells | Stem Cells | 2018 | 384 |
| 50 | Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study | Lancet Diabetes and Endocrinology,the | 2016 | 381 |
