| # | Title | Journal | Year | Citations |
|---|
| 1 | Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis | Nature Genetics | 2010 | 1,631 |
| 2 | Circulating tumour cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents | Annals of Oncology | 2010 | 183 |
| 3 | Patterns of metachronous metastases after curative treatment of colorectal cancer | Cancer Epidemiology | 2014 | 165 |
| 4 | Prevention of chemotherapy-induced hair loss by scalp cooling | Annals of Oncology | 2005 | 152 |
| 5 | The Effects of a Mindfulness-Based Intervention on Emotional Distress, Quality of Life, and HbA1c in Outpatients With Diabetes (DiaMind) | Diabetes Care | 2013 | 129 |
| 6 | Metachronous peritoneal carcinomatosis after curative treatment of colorectal cancer | European Journal of Surgical Oncology | 2014 | 123 |
| 7 | Clinical management of women with metastatic breast cancer: a descriptive study according to age group | BMC Cancer | 2006 | 114 |
| 8 | Iron Metabolism Is Associated With Adipocyte Insulin Resistance and Plasma Adiponectin | Diabetes Care | 2013 | 95 |
| 9 | Timing of adjuvant chemotherapy and its relation to survival among patients with stage III colon cancer | European Journal of Cancer | 2015 | 95 |
| 10 | Prophylaxis of Irinotecan‐Induced Diarrhea with Neomycin and Potential Role for UGT1A1*28 Genotype Screening: A Double‐Blind, Randomized, Placebo‐Controlled Study | Oncologist | 2006 | 81 |
| 11 | Population-based survival of patients with peritoneal carcinomatosis from colorectal origin in the era of increasing use of palliative chemotherapy | Annals of Oncology | 2011 | 81 |
| 12 | Mindfulness-based cognitive therapy for people with diabetes and emotional problems: Long-term follow-up findings from the DiaMind randomized controlled trial | Journal of Psychosomatic Research | 2014 | 71 |
| 13 | Hodgkin disease in the elderly. A registry-based analysis | Cancer | 1992 | 68 |
| 14 | Complement Factor 3 Is Associated With Insulin Resistance and With Incident Type 2 Diabetes Over a 7-Year Follow-up Period: The CODAM Study | Diabetes Care | 2014 | 68 |
| 15 | Trends in incidence, treatment and survival of small bowel adenocarcinomas between 1999 and 2013: a population-based study in The Netherlands | Acta Oncológica | 2016 | 68 |
| 16 | Glucose, insulin and the brain: modulation of cognition and synaptic plasticity in health and disease: a preface | European Journal of Pharmacology | 2004 | 66 |
| 17 | Malignant transformation of monoclonal gammopathy of undetermined significance among out-patients of a community hospital in Southeastern Netherlands | British Journal of Haematology | 1995 | 63 |
| 18 | The safety of breast-conserving therapy in patients with breast cancer aged ≤40 years | Cancer | 2007 | 56 |
| 19 | Combined student ratings and self-assessment provide useful feedback for clinical teachers | Advances in Health Sciences Education | 2010 | 50 |
| 20 | Challenging the dogma of colorectal peritoneal metastases as an untreatable condition: Results of a population-based study | European Journal of Cancer | 2016 | 45 |
| 21 | Interferon-α as maintenance therapy in patients with multiple myeloma | Annals of Oncology | 2005 | 43 |
| 22 | Impact of chemotherapy on health status and symptom burden of colon cancer survivors: A population-based study | European Journal of Cancer | 2011 | 42 |
| 23 | Cytomegalovirus-induced thrombocytopenia and haemolysis in an immunocompetent adult | British Journal of Haematology | 1996 | 40 |
| 24 | Low-grade inflammation and insulin resistance independently explain substantial parts of the association between body fat and serum C3: The CODAM study | Metabolism: Clinical and Experimental | 2012 | 40 |
| 25 | Iron metabolism is prospectively associated with insulin resistance and glucose intolerance over a 7-year follow-up period: the CODAM study | Acta Diabetologica | 2015 | 40 |
| 26 | Significant improvement in survival of patients presenting with metastatic colon cancer in the south of The Netherlands from 1990 to 2004 | Annals of Oncology | 2008 | 39 |
| 27 | Treatment of acute hepatitis C genotypes 1 and 4 with 8 weeks of grazoprevir plus elbasvir (DAHHS2): an open-label, multicentre, single-arm, phase 3b trial | The Lancet Gastroenterology and Hepatology | 2019 | 39 |
| 28 | Microalbuminuria and Cardiovascular Autonomic Dysfunction Are Independently Associated With Cardiovascular Mortality: Evidence for Distinct Pathways: The Hoorn Study | Diabetes Care | 2009 | 38 |
| 29 | High prevalence of diabetes mellitus in patients with liver cirrhosis | Diabetic Medicine | 2010 | 38 |
| 30 | Implementation of osteoporosis guidelines: a survey of five large fracture liaison services in the Netherlands | Osteoporosis International | 2011 | 38 |
| 31 | Activated complement factor 3 is associated with liver fat and liver enzymes: the CODAM study | European Journal of Clinical Investigation | 2013 | 38 |
| 32 | Disappearance of prognostic significance of histopathological grading of nodular sclerosing Hodgkin's disease for unselected patients, 1972-92 | British Journal of Haematology | 1997 | 34 |
| 33 | Chemotherapy and cognitive complaints in women with breast cancer | Psycho-Oncology | 2013 | 34 |
| 34 | Impact of the Advanced Practice Provider in Adult Critical Care: A Systematic Review and Meta-Analysis* | Critical Care Medicine | 2019 | 34 |
| 35 | Prospective study on clinical effects of renal replacement therapy in treatment-resistant congestive heart failure | Nephrology Dialysis Transplantation | 2012 | 33 |
| 36 | Acute renal failure after cardiovascular surgery. Current concepts in pathophysiology, prevention and treatment | European Heart Journal | 1989 | 32 |
| 37 | Doxorubicin/cyclophosphamide with concurrent versus sequential docetaxel as neoadjuvant treatment in patients with breast cancer | European Journal of Cancer | 2013 | 32 |
| 38 | Randomised Phase III study of biweekly 24-h infusion of high-dose 5FU with folinic acid and oxaliplatin versus monthly plus 5-FU/folinic acid in first-line treatment of advanced colorectal cancer | Annals of Oncology | 2006 | 30 |
| 39 | Ten weeks to live: A population-based study on treatment and survival of patients with metastatic pancreatic cancer in the south of the Netherlands | Acta Oncológica | 2015 | 30 |
| 40 | Validation, revision and extension of the Follicular Lymphoma International Prognostic Index (FLIPI) in a population-based setting | Annals of Oncology | 2009 | 29 |
| 41 | Chronic Lymphocytic Leukaemia in the Netherlands: Trends in incidence, treatment and survival, 1989–2008 | European Journal of Cancer | 2012 | 29 |
| 42 | Comparison of acidified glycerol lysis test, Pink test and osmotic fragility test in hereditary spherocytosis: Effect of incubation | European Journal of Haematology | 1988 | 27 |
| 43 | Pregnancy in classic galactosemia despite undetectable anti-Müllerian hormone | Fertility and Sterility | 2009 | 27 |
| 44 | The Value of 18F-FDG PET/CT in Diagnosis and During Follow-up in 273 Patients with Chronic Q Fever | Journal of Nuclear Medicine | 2018 | 26 |
| 45 | Diabetes mellitus at the time of diagnosis ofcirrhosis is associated with higher incidence of spontaneous bacterial peritonitis, but not with increased mortality | Clinical Science | 2013 | 25 |
| 46 | Consideration of QRS complex in addition to ST-segment abnormalities in the estimated “risk region” during acute anterior myocardial infarction | Journal of Electrocardiology | 2011 | 23 |
| 47 | Chemotherapy as palliative treatment for peritoneal carcinomatosis of gastric origin | Acta Oncológica | 2014 | 23 |
| 48 | AR splice variants in circulating tumor cells of patients with castration‐resistant prostate cancer: relation with outcome to cabazitaxel | Molecular Oncology | 2019 | 23 |
| 49 | Improved survival of Hodgkin's patients in South-East Netherlands since 1972 | European Journal of Cancer | 1997 | 22 |
| 50 | Does long-term survival exist in pancreatic adenocarcinoma? | Acta Oncológica | 2016 | 22 |
