# | Title | Journal | Year | Citations |
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1 | Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis | Diabetologia | 1992 | 2,938 |
2 | Fetal and infant growth and impaired glucose tolerance at age 64. | BMJ: British Medical Journal | 1991 | 2,326 |
3 | Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth | Diabetologia | 1993 | 2,271 |
4 | The thrifty phenotype hypothesis | British Medical Bulletin | 2001 | 2,196 |
5 | Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease | Nature Genetics | 2004 | 2,188 |
6 | Lysosomes: fusion and function | Nature Reviews Molecular Cell Biology | 2007 | 1,397 |
7 | An SCN9A channelopathy causes congenital inability to experience pain | Nature | 2006 | 1,353 |
8 | Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene | Nature Genetics | 1997 | 1,068 |
9 | Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling | Biochemical Journal | 1998 | 924 |
10 | TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction | Nature Genetics | 2009 | 817 |
11 | Plasma membrane contributes to the formation of pre-autophagosomal structures | Nature Cell Biology | 2010 | 755 |
12 | PPAR and human metabolic disease | Journal of Clinical Investigation | 2006 | 717 |
13 | Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells | Nature Medicine | 2011 | 714 |
14 | PGP 9.5—a new marker for vertebrate neurons and neuroendocrine cells | Brain Research | 1983 | 696 |
15 | Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency | Journal of Clinical Investigation | 2002 | 670 |
16 | TNF‐α and adipocyte biology | FEBS Letters | 2008 | 624 |
17 | Glucose Sensing in L Cells: A Primary Cell Study | Cell Metabolism | 2008 | 624 |
18 | Clinical and Molecular Genetic Spectrum of Congenital Deficiency of the Leptin Receptor | New England Journal of Medicine | 2007 | 610 |
19 | Genetic cause of hyperglycaemia and response to treatment in diabetes | Lancet, The | 2003 | 526 |
20 | A Family with Severe Insulin Resistance and Diabetes Due to a Mutation in AKT2 | Science | 2004 | 509 |
21 | The Hormonal Control of Food Intake | Cell | 2007 | 508 |
22 | Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension | Nature Genetics | 2013 | 446 |
23 | Fetal and infant growth and cardiovascular risk factors in women | BMJ: British Medical Journal | 1995 | 406 |
24 | Sulfonylurea Stimulation of Insulin Secretion | Diabetes | 2002 | 393 |
25 | Fetal testosterone and autistic traits | British Journal of Psychology | 2009 | 376 |
26 | DNA damage, cellular senescence and organismal ageing: causal or correlative? | Nucleic Acids Research | 2007 | 374 |
27 | Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy | Nature Communications | 2014 | 374 |
28 | Mutations in the Pericentrin ( PCNT ) Gene Cause Primordial Dwarfism | Science | 2008 | 370 |
29 | Sensitive and specific two-site immunoradiometric assays for human insulin, proinsulin, 65-66 split and 32-33 split proinsulins | Biochemical Journal | 1989 | 367 |
30 | Signalling by insulin and IGF receptors: supporting acts and new players | Journal of Molecular Endocrinology | 2011 | 364 |
31 | Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: Effects of brefeldin A and G protein activators | Cell | 1992 | 355 |
32 | Clathrin and adaptors | Biochimica Et Biophysica Acta - Molecular Cell Research | 1998 | 349 |
33 | Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake | Neuron | 2006 | 345 |
34 | Isolation of PGP 9.5, a New Human Neurone-Specific Protein Detected by High-Resolution Two-Dimensional Electrophoresis | Journal of Neurochemistry | 1983 | 341 |
35 | A Novel Glucose-Sensing Mechanism Contributing to Glucagon-Like Peptide-1 Secretion From the GLUTag Cell Line | Diabetes | 2003 | 341 |
36 | Glucose intolerance and impairment of insulin secretion in relation to vitamin D deficiency in East London Asians | Diabetologia | 1995 | 337 |
37 | The role of clathrin, adaptors and dynamin in endocytosis | Current Opinion in Cell Biology | 1994 | 328 |
38 | Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5 | Journal of Cell Science | 2009 | 328 |
39 | The Role of Intraorganellar Ca2+In Late Endosome–Lysosome Heterotypic Fusion and in the Reformation of Lysosomes from Hybrid Organelles | Journal of Cell Biology | 2000 | 325 |
40 | Organ-selective growth in the offspring of protein-restricted mothers | British Journal of Nutrition | 1996 | 323 |
41 | Fetal Growth and Glucose and Insulin Metabolism in Four‐year‐old Indian Children | Diabetic Medicine | 1995 | 313 |
42 | Diabetes risk score: towards earlier detection of Type 2 diabetes in general practice | Diabetes/Metabolism Research and Reviews | 2000 | 308 |
43 | INSULIN DEFICIENCY IN NON-INSULIN-DEPENDENT DIABETES | Lancet, The | 1989 | 300 |
44 | Differential Lipid Partitioning Between Adipocytes and Tissue Macrophages Modulates Macrophage Lipotoxicity and M2/M1 Polarization in Obese Mice | Diabetes | 2011 | 297 |
45 | Fishing in the Stream of Diabetes: From Measuring Insulin to the Control of Fetal Organogenesis | Biochemical Society Transactions | 1996 | 296 |
46 | Foetal testosterone and eye contact in 12-month-old human infants | | 2002 | 296 |
47 | Recycle your receptors with retromer | Trends in Cell Biology | 2005 | 284 |
48 | A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex | Nature | 2008 | 280 |
49 | Pain perception is altered by a nucleotide polymorphism in SCN9A | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 279 |
50 | Fetal Testosterone Predicts Sexually Differentiated Childhood Behavior in Girls and in Boys | Psychological Science | 2009 | 272 |