# | Title | Journal | Year | Citations |
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1 | Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma | New England Journal of Medicine | 1991 | 5,222 |
2 | Global variation in copy number in the human genome | Nature | 2006 | 3,831 |
3 | Mesenchymal stem cells within tumour stroma promote breast cancer metastasis | Nature | 2007 | 2,874 |
4 | Somatic mutations affect key pathways in lung adenocarcinoma | Nature | 2008 | 2,694 |
5 | Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins | Science | 1989 | 2,274 |
6 | An immunogenic personal neoantigen vaccine for patients with melanoma | Nature | 2017 | 2,112 |
7 | Landscape of somatic mutations in 560 breast cancer whole-genome sequences | Nature | 2016 | 1,760 |
8 | Identification of an inducible endothelial-leukocyte adhesion molecule. | Proceedings of the National Academy of Sciences of the United States of America | 1987 | 1,521 |
9 | The Essential Medicinal Chemistry of Curcumin | Journal of Medicinal Chemistry | 2017 | 1,291 |
10 | T-cell invigoration to tumour burden ratio associated with anti-PD-1 response | Nature | 2017 | 1,280 |
11 | Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints | Nature Communications | 2016 | 1,163 |
12 | Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade | Nature Immunology | 2019 | 1,148 |
13 | Characterizing the cancer genome in lung adenocarcinoma | Nature | 2007 | 1,020 |
14 | The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis | Cell Metabolism | 2005 | 1,006 |
15 | Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial | Nature | 2019 | 956 |
16 | Novel mutant-selective EGFR kinase inhibitors against EGFR T790M | Nature | 2009 | 886 |
17 | Landscape of genomic alterations in cervical carcinomas | Nature | 2014 | 708 |
18 | TPM3-ALK and TPM4-ALK Oncogenes in Inflammatory Myofibroblastic Tumors | American Journal of Pathology | 2000 | 659 |
19 | Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity | Cell | 2019 | 642 |
20 | An inducible endothelial cell surface glycoprotein mediates melanoma adhesion | Science | 1989 | 628 |
21 | PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress | Cancer Cell | 2013 | 600 |
22 | Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19 | Cell | 2020 | 599 |
23 | COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets | Nature | 2021 | 537 |
24 | Clinicopathological features of acute kidney injury associated with immune checkpoint inhibitors | Kidney International | 2016 | 524 |
25 | Assessment of Resistance Mechanisms and Clinical Implications in Patients WithEGFRT790M–Positive Lung Cancer and Acquired Resistance to Osimertinib | JAMA Oncology | 2018 | 522 |
26 | The biology and treatment of EML4-ALK non-small cell lung cancer | European Journal of Cancer | 2010 | 516 |
27 | p63 protects the female germ line during meiotic arrest | Nature | 2006 | 479 |
28 | SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression | Nature | 2011 | 462 |
29 | A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response | Nature | 2012 | 430 |
30 | Targetable genetic features of primary testicular and primary central nervous system lymphomas | Blood | 2016 | 429 |
31 | MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma | Science Translational Medicine | 2018 | 425 |
32 | Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles | Science Advances | 2018 | 416 |
33 | DHODH modulates transcriptional elongation in the neural crest and melanoma | Nature | 2011 | 411 |
34 | Mouse Inducible Costimulatory Molecule (ICOS) Expression Is Enhanced by CD28 Costimulation and Regulates Differentiation of CD4+ T Cells | Journal of Immunology | 2000 | 400 |
35 | PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies | Nature | 2014 | 386 |
36 | Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease | Nature Communications | 2020 | 371 |
37 | CD11b/CD18 Acts in Concert with CD14 and Toll-Like Receptor (TLR) 4 to Elicit Full Lipopolysaccharide and Taxol-Inducible Gene Expression | Journal of Immunology | 2001 | 368 |
38 | A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 350 |
39 | A targeted mutational landscape of angioimmunoblastic T-cell lymphoma | Blood | 2014 | 345 |
40 | Highly efficient therapeutic gene editing of human hematopoietic stem cells | Nature Medicine | 2019 | 344 |
41 | Immunopathologic Characterization of a Monoclonal Antibody that Recognizes Common Surface Antigens of Human Ovarian Tumors of Serous, Endometrioid, and Clear Cell Types | American Journal of Clinical Pathology | 1983 | 338 |
42 | TNF Family Member B Cell-Activating Factor (BAFF) Receptor-Dependent and -Independent Roles for BAFF in B Cell Physiology | Journal of Immunology | 2004 | 335 |
43 | A large peptidome dataset improves HLA class I epitope prediction across most of the human population | Nature Biotechnology | 2020 | 324 |
44 | The single-cell transcriptomic landscape of early human diabetic nephropathy | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 323 |
45 | Iron addiction: a novel therapeutic target in ovarian cancer | Oncogene | 2017 | 320 |
46 | Diagnostic Relevance of Clonal Cytogenetic Aberrations in Malignant Soft-Tissue Tumors | New England Journal of Medicine | 1991 | 305 |
47 | Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton | Cell | 2016 | 301 |
48 | The BRAF Pseudogene Functions as a Competitive Endogenous RNA and Induces Lymphoma In Vivo | Cell | 2015 | 293 |
49 | IL-17 and TNF-α Sustain Neutrophil Recruitment during Inflammation through Synergistic Effects on Endothelial Activation | Journal of Immunology | 2012 | 292 |
50 | The Requirement for Cyclin D Function in Tumor Maintenance | Cancer Cell | 2012 | 284 |