| # | Title | Journal | Year | Citations |
|---|
| 1 | P[acman]: A BAC Transgenic Platform for Targeted Insertion of Large DNA Fragments in D. melanogaster | Science | 2006 | 1,242 |
| 2 | The BDGP Gene Disruption Project | Genetics | 2004 | 774 |
| 3 | Synaptic Mitochondria Are Critical for Mobilization of Reserve Pool Vesicles at Drosophila Neuromuscular Junctions | Neuron | 2005 | 734 |
| 4 | The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis | Nature Cell Biology | 2006 | 673 |
| 5 | Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway | Nature Cell Biology | 2003 | 652 |
| 6 | p63 is the molecular switch for initiation of an epithelial stratification program | Genes and Development | 2004 | 564 |
| 7 | Math1 Expression Redefines the Rhombic Lip Derivatives and Reveals Novel Lineages within the Brainstem and Cerebellum | Neuron | 2005 | 519 |
| 8 | Axon-Glia Interactions and the Domain Organization of Myelinated Axons Requires Neurexin IV/Caspr/Paranodin | Neuron | 2001 | 510 |
| 9 | Senseless, a Zn Finger Transcription Factor, Is Necessary and Sufficient for Sensory Organ Development in Drosophila | Cell | 2000 | 473 |
| 10 | Identification of diverse astrocyte populations and their malignant analogs | Nature Neuroscience | 2017 | 410 |
| 11 | Synaptic Vesicle Size and Number Are Regulated by a Clathrin Adaptor Protein Required for Endocytosis | Neuron | 1998 | 397 |
| 12 | Genetic Manipulation of Genes and Cells in the Nervous System of the Fruit Fly | Neuron | 2011 | 395 |
| 13 | Drosophila parkinmutants have decreased mass and cell size and increased sensitivity to oxygen radical stress | Development (Cambridge) | 2004 | 387 |
| 14 | Modulating F-actin organization induces organ growth by affecting the Hippo pathway | EMBO Journal | 2011 | 376 |
| 15 | Drosophilatools and assays for the study of human diseases | DMM Disease Models and Mechanisms | 2016 | 367 |
| 16 | Huntingtin functions as a scaffold for selective macroautophagy | Nature Cell Biology | 2015 | 336 |
| 17 | Hippo pathway deficiency reverses systolic heart failure after infarction | Nature | 2017 | 333 |
| 18 | The Drosophila Gene Disruption Project: Progress Using Transposons With Distinctive Site Specificities | Genetics | 2011 | 330 |
| 19 | Developmental genetics of the female reproductive tract in mammals | Nature Reviews Genetics | 2003 | 321 |
| 20 | A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila | ELife | 2015 | 320 |
| 21 | Distinct and sequential tissue-specific activities of the LIM-class homeobox geneLim1for tubular morphogenesis during kidney development | Development (Cambridge) | 2005 | 307 |
| 22 | Shar-pei mediates cell proliferation arrest during imaginal disc growth inDrosophila | Development (Cambridge) | 2002 | 302 |
| 23 | The v-ATPase V 0 Subunit a1 Is Required for a Late Step in Synaptic Vesicle Exocytosis in Drosophila | Cell | 2005 | 297 |
| 24 | ATAXIN-1 Interacts with the Repressor Capicua in Its Native Complex to Cause SCA1 Neuropathology | Cell | 2006 | 284 |
| 25 | Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase | Nature | 2007 | 279 |
| 26 | The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 275 |
| 27 | Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling | Cell | 2008 | 272 |
| 28 | Thirty-One Flavors of Drosophila Rab Proteins | Genetics | 2007 | 264 |
| 29 | A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila | Genes and Development | 1999 | 250 |
| 30 | Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo | Nature Structural and Molecular Biology | 2005 | 245 |
| 31 | The zinc finger transcription factorGfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival | Development (Cambridge) | 2003 | 233 |
| 32 | A Distal Axonal Cytoskeleton Forms an Intra-Axonal Boundary that Controls Axon Initial Segment Assembly | Cell | 2012 | 230 |
| 33 | Engineering chromosomal rearrangements in mice | Nature Reviews Genetics | 2001 | 229 |
| 34 | Adult Neural Function Requires MeCP2 | Science | 2011 | 227 |
| 35 | Dap160/Intersectin Acts as a Stabilizing Scaffold Required for Synaptic Development and Vesicle Endocytosis | Neuron | 2004 | 225 |
| 36 | WNT4 is a key regulator of normal postnatal uterine development and progesterone signaling during embryo implantation and decidualization in the mouse | FASEB Journal | 2011 | 221 |
| 37 | Drosophila Fragile X Protein, DFXR, Regulates Neuronal Morphology and Function in the Brain | Neuron | 2002 | 215 |
| 38 | A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects | Nature | 2011 | 213 |
| 39 | Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans | Science | 2015 | 211 |
| 40 | p63 induces key target genes required for epidermal morphogenesis | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 206 |
| 41 | An AT-Hook Domain in MeCP2 Determines the Clinical Course of Rett Syndrome and Related Disorders | Cell | 2013 | 201 |
| 42 | When cell biology meets development: endocytic regulation of signaling pathways | Genes and Development | 2002 | 194 |
| 43 | Synaptotagmin I, a Ca2+ sensor for neurotransmitter release | Trends in Neurosciences | 2003 | 194 |
| 44 | Smad5 is required for mouse primordial germ cell development | Mechanisms of Development | 2001 | 191 |
| 45 | The AXH Domain of Ataxin-1 Mediates Neurodegeneration through Its Interaction with Gfi-1/Senseless Proteins | Cell | 2005 | 189 |
| 46 | Emerging technologies for gene manipulation in Drosophila melanogaster | Nature Reviews Genetics | 2005 | 186 |
| 47 | Requirement ofLim1for female reproductive tract development | Development (Cambridge) | 2004 | 182 |
| 48 | Sec15, a Component of the Exocyst, Promotes Notch Signaling during the Asymmetric Division of Drosophila Sensory Organ Precursors | Developmental Cell | 2005 | 182 |
| 49 | The roof plate regulates cerebellar cell-type specification and proliferation | Development (Cambridge) | 2006 | 180 |
| 50 | Follistatin Regulates Enamel Patterning in Mouse Incisors by Asymmetrically Inhibiting BMP Signaling and Ameloblast Differentiation | Developmental Cell | 2004 | 179 |
