| # | Title | Journal | Year | Citations |
|---|
| 1 | Model-based Analysis of ChIP-Seq (MACS) | Genome Biology | 2008 | 13,517 |
| 2 | SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS | Annual Review of Cell and Developmental Biology | 2005 | 1,670 |
| 3 | Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy | Journal of the National Cancer Institute | 2008 | 1,632 |
| 4 | p53 mutant mice that display early ageing-associated phenotypes | Nature | 2002 | 1,373 |
| 5 | Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators | Cell | 2002 | 1,345 |
| 6 | Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 1,257 |
| 7 | SIN1/MIP1 Maintains rictor-mTOR Complex Integrity and Regulates Akt Phosphorylation and Substrate Specificity | Cell | 2006 | 1,231 |
| 8 | Spatiotemporal Rescue of Memory Dysfunction in Drosophila | Science | 2003 | 1,167 |
| 9 | BSMAP: whole genome bisulfite sequence MAPping program | BMC Bioinformatics | 2009 | 960 |
| 10 | Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 909 |
| 11 | Coregulator Function: A Key to Understanding Tissue Specificity of Selective Receptor Modulators | Endocrine Reviews | 2004 | 860 |
| 12 | Rb targets histone H3 methylation and HP1 to promoters | Nature | 2001 | 840 |
| 13 | Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation | Cell | 2009 | 815 |
| 14 | Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer | Cell | 2009 | 797 |
| 15 | Intercellular Communication in the Mammalian Ovary: Oocytes Carry the Conversation | Science | 2002 | 790 |
| 16 | JHDM2A, a JmjC-Containing H3K9 Demethylase, Facilitates Transcription Activation by Androgen Receptor | Cell | 2006 | 737 |
| 17 | Farnesoid X receptor is essential for normal glucose homeostasis | Journal of Clinical Investigation | 2006 | 716 |
| 18 | Oocyte-Specific Deletion of Pten Causes Premature Activation of the Primordial Follicle Pool | Science | 2008 | 715 |
| 19 | FoxM1 is required for execution of the mitotic programme and chromosome stability | Nature Cell Biology | 2005 | 697 |
| 20 | Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways | Nature Genetics | 2005 | 680 |
| 21 | Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor | Science | 2001 | 673 |
| 22 | Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications | Nature Biotechnology | 2010 | 647 |
| 23 | The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism | Nature | 2000 | 635 |
| 24 | Subgroup of Reproductive Functions of Progesterone Mediated by Progesterone Receptor-B Isoform | Science | 2000 | 635 |
| 25 | The Increasing Complexity of the Cancer Stem Cell Paradigm | Science | 2009 | 630 |
| 26 | Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems | Genes and Development | 2000 | 609 |
| 27 | Thymosin β4 induces adult epicardial progenitor mobilization and neovascularization | Nature | 2007 | 605 |
| 28 | WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 599 |
| 29 | Spatiotemporal Gene Expression Targeting with the TARGET and Gene-Switch Systems in Drosophila | Science Signaling | 2004 | 595 |
| 30 | Activating Mutations in theABCC8Gene in Neonatal Diabetes Mellitus | New England Journal of Medicine | 2006 | 591 |
| 31 | Nuclear Receptor-Dependent Bile Acid Signaling Is Required for Normal Liver Regeneration | Science | 2006 | 588 |
| 32 | Deletion of Ghrelin Impairs neither Growth nor Appetite | Molecular and Cellular Biology | 2003 | 579 |
| 33 | Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3 | EMBO Journal | 2000 | 567 |
| 34 | Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity | Nature | 2005 | 567 |
| 35 | BAP1 links metabolic regulation of ferroptosis to tumour suppression | Nature Cell Biology | 2018 | 565 |
| 36 | The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36 | Nature | 2006 | 563 |
| 37 | MAPK3/1 (ERK1/2) in Ovarian Granulosa Cells Are Essential for Female Fertility | Science | 2009 | 559 |
| 38 | Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming | Nature | 2017 | 555 |
| 39 | Modelling breast cancer: one size does not fit all | Nature Reviews Cancer | 2007 | 545 |
| 40 | Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling | Clinical Cancer Research | 2002 | 544 |
| 41 | OLFACTORY MEMORY FORMATION INDROSOPHILA: From Molecular to Systems Neuroscience | Annual Review of Neuroscience | 2005 | 530 |
| 42 | The 26S Proteasome Is Required for Estrogen Receptor-α and Coactivator Turnover and for Efficient Estrogen Receptor-α Transactivation | Molecular Cell | 2000 | 526 |
| 43 | Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal | Cell Stem Cell | 2014 | 524 |
| 44 | SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation | Nature | 2012 | 503 |
| 45 | Endoplasmic reticulum stress signals in the tumour and its microenvironment | Nature Reviews Cancer | 2021 | 499 |
| 46 | The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 497 |
| 47 | A Natural Product That Lowers Cholesterol As an Antagonist Ligand for FXR | Science | 2002 | 491 |
| 48 | Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity | Science | 2018 | 489 |
| 49 | Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 484 |
| 50 | Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 481 |
