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Top Articles

#TitleJournalYearCitations
1Nuclease P1-mediated enhancement of sensitivity of 32P-Postlabeling test for structurally diverse DNA adductsCarcinogenesis19861,175
2Nrf2 signaling in coordinated activation of antioxidant gene expressionFree Radical Biology and Medicine20041,093
3Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymesOncogene1998525
4Macromolecular modeling and design in Rosetta: recent methods and frameworksNature Methods2020513
5Phosphorylation of Nrf2 at Ser40 by Protein Kinase C in Response to Antioxidants Leads to the Release of Nrf2 from INrf2, but Is Not Required for Nrf2 Stabilization/Accumulation in the Nucleus and Transcriptional Activation of Antioxidant Response Element-mediated NAD(P)H:Quinone Oxidoreductase-1 Gene ExpressionJournal of Biological Chemistry2003450
6Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal productFree Radical Biology and Medicine1999439
7Metallo‐β‐lactamase structure and functionAnnals of the New York Academy of Sciences2013425
8GSK-3β Acts Upstream of Fyn Kinase in Regulation of Nuclear Export and Degradation of NF-E2 Related Factor 2Journal of Biological Chemistry2007415
9Mitochondrial Fission Triggered by Hyperglycemia Is Mediated by ROCK1 Activation in Podocytes and Endothelial CellsCell Metabolism2012395
10Regulation of genes encoding NAD(P)H:quinone oxidoreductasesFree Radical Biology and Medicine2000382
11Alteration of ethanol self-administration by naltrexoneLife Sciences1980377
12Bach1 Competes with Nrf2 Leading to Negative Regulation of the Antioxidant Response Element (ARE)-mediated NAD(P)H:Quinone Oxidoreductase 1 Gene Expression and Induction in Response to AntioxidantsJournal of Biological Chemistry2005337
13Detection of smoking-related covalent DNA adducts in human placentaScience1986298
14Laminar Flow Induction of Antioxidant Response Element-mediated Genes in Endothelial CellsJournal of Biological Chemistry2003289
15Silver staining, immunofluorescence, and immunoelectron microscopic localization of nucleolar phosphoproteins B23 and C23Chromosoma1984278
16The Treacher Collins syndrome ( TCOF1 ) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factorProceedings of the National Academy of Sciences of the United States of America2004275
17Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 geneOncogene2001269
18Cloning and Characterization of GEF-H1, a Microtubule-associated Guanine Nucleotide Exchange Factor for Rac and Rho GTPasesJournal of Biological Chemistry1998266
19Microbial Genetic Composition Tunes Host LongevityCell2017256
20Comparison of Nucleolar Proteins of Normal Rat Liver and Novikoff Hepatoma Ascites Cells by Two-Dimensional Polyacrylamide Gel ElectrophoresisProceedings of the National Academy of Sciences of the United States of America1973249
21MicroRNA-29c Is a Signature MicroRNA under High Glucose Conditions That Targets Sprouty Homolog 1, and Its in Vivo Knockdown Prevents Progression of Diabetic NephropathyJournal of Biological Chemistry2011238
22Disruption of the DT Diaphorase (NQO1) Gene in Mice Leads to Increased Menadione ToxicityJournal of Biological Chemistry1998237
23Localization of nucleolar phosphoproteins B23 and C23 during mitosisExperimental Cell Research1983233
24Low molecular weight RNA associated with 28 s nucleolar RNAJournal of Molecular Biology1970215
25Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic DissectionsAmerican Journal of Human Genetics2013197
26Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of γ-glutamylcysteine synthetase heavy subunit geneBiochemical Pharmacology2000193
27Small Maf (MafG and MafK) Proteins Negatively Regulate Antioxidant Response Element-mediated Expression and Antioxidant Induction of the NAD(P)H:Quinone Oxidoreductase1 GeneJournal of Biological Chemistry2000189
28Heterogeneity of human colon carcinomaCancer and Metastasis Reviews1984179
29TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector.Journal of Cell Biology1992178
30In Vivo Role of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) in the Regulation of Intracellular Redox State and Accumulation of Abdominal Adipose TissueJournal of Biological Chemistry2001176
31Antioxidant regulation of genes encoding enzymes that detoxify xenobiotics and carcinogensCurrent Topics in Cellular Regulation2001172
32Gamma-monomethyl phosphate: a cap structure in spliceosomal U6 small nuclear RNA.Proceedings of the National Academy of Sciences of the United States of America1989171
33Nuclear Import and Export Signals in Control of Nrf2Journal of Biological Chemistry2005171
34An Auto-regulatory Loop between Stress Sensors INrf2 and Nrf2 Controls Their Cellular AbundanceJournal of Biological Chemistry2007170
35Primary Sequence of U-1 Nuclear Ribonucleic Acid of Novikoff Hepatoma Ascites CellsJournal of Biological Chemistry1974167
36Quantitative Imaging of Glutathione in Live Cells Using a Reversible Reaction-Based Ratiometric Fluorescent ProbeACS Chemical Biology2015164
3732P-adduct assay: comparative recoveries of structurally diverse DNA adducts in the various enhancement proceduresCarcinogenesis1988163
38Covalent DNA Damage in Tissues of Cigarette Smokers as Determined by 32P-Postlabeling AssayJournal of the National Cancer Institute1989155
39An epigenomic approach to therapy for tamoxifen-resistant breast cancerCell Research2014155
40Phosphorylation of Tyrosine 568 Controls Nuclear Export of Nrf2Journal of Biological Chemistry2006154
41Combination of hypothyroidism and stress abolishes early LTP in the CA1 but not dentate gyrus of hippocampus of adult ratsBrain Research2001151
42Localization of phosphoprotein C23 to nucleolar structures and to the nucleolus organizer regionsExperimental Cell Research1981150
43Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene SilencingJournal of the American Chemical Society2012150
44Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1Cancer Research2014145
45C23 Interacts with B23, A Putative Nucleolar-Localization-Signal-Binding ProteinFEBS Journal1996144
46Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic StudiesJournal of the American Chemical Society2011144
47Further evidence that phosphoprotein C23 (110 kD/pI 5.1) is the nucleolar silver staining proteinExperimental Cell Research1984141
48Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondiiJournal of Experimental Medicine2011141
49Activity-Dependent Intracellular Acidification Correlates with the Duration of Seizure ActivityJournal of Neuroscience2000139
50The Treacher Collins syndrome (TCOF1) gene product is involved in pre-rRNA methylationHuman Molecular Genetics2005136