| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses | Neoplasia | 2017 | 4,166 |
| 3 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
| 4 | Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy | Cell | 2005 | 3,204 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 6 | Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma | Gastroenterology | 2012 | 2,753 |
| 7 | Doppler Tissue Imaging: A Noninvasive Technique for Evaluation of Left Ventricular Relaxation and Estimation of Filling Pressures | Journal of the American College of Cardiology | 1997 | 2,720 |
| 8 | Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock | Intensive Care Medicine | 2004 | 2,079 |
| 9 | The inflammatory response in myocardial infarction | Cardiovascular Research | 2002 | 1,729 |
| 10 | Leptin Regulates Bone Formation via the Sympathetic Nervous System | Cell | 2002 | 1,530 |
| 11 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 12 | Kyoto global consensus report onHelicobacter pylorigastritis | Gut | 2015 | 1,256 |
| 13 | Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma | Gastroenterology | 2004 | 1,105 |
| 14 | Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the studies of left ventricular dysfunction (SOLVD) | Journal of the American College of Cardiology | 1996 | 1,098 |
| 15 | Replication of human noroviruses in stem cell–derived human enteroids | Science | 2016 | 1,056 |
| 16 | Epidemiology of Hepatocellular Carcinoma | Hepatology | 2021 | 1,007 |
| 17 | Epidemiology of Hepatocellular Carcinoma | Journal of Clinical Gastroenterology | 2013 | 996 |
| 18 | The Metabolic Syndrome and 11-Year Risk of Incident Cardiovascular Disease in the Atherosclerosis Risk in Communities Study | Diabetes Care | 2005 | 988 |
| 19 | Hyperuricemia induces endothelial dysfunction | Kidney International | 2005 | 968 |
| 20 | Mechanisms of Endocrine Resistance in Breast Cancer | Annual Review of Medicine | 2011 | 963 |
| 21 | Mechanism of myocardial "stunning". | Circulation | 1990 | 937 |
| 22 | Low-Grade Systemic Inflammation and the Development of Type 2 Diabetes: The Atherosclerosis Risk in Communities Study | Diabetes | 2003 | 908 |
| 23 | Cytokines and Cytokine Receptors in Advanced Heart Failure | Circulation | 2001 | 903 |
| 24 | Hippocampal synaptic transmission enhanced by low concentrations of nicotine | Nature | 1996 | 892 |
| 25 | Epidemiology of Helicobacter pylori in an asymptomatic population in the United States | Gastroenterology | 1991 | 891 |
| 26 | Tissue-factor–bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation | Blood | 2005 | 887 |
| 27 | Inflammatory Mediators and the Failing Heart | Circulation Research | 2002 | 886 |
| 28 | Prevalence of Depression and Depressive Symptoms Among Resident Physicians | JAMA - Journal of the American Medical Association | 2015 | 886 |
| 29 | Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins | Nature | 1990 | 870 |
| 30 | Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention | Nature Reviews Gastroenterology and Hepatology | 2021 | 867 |
| 31 | Nuclear factor-?B: its role in health and disease | Journal of Molecular Medicine | 2004 | 834 |
| 32 | Helicobacter pylori treatment in the era of increasing antibiotic resistance | Gut | 2010 | 821 |
| 33 | Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration | Nature | 2015 | 818 |
| 34 | Toll-like Receptor 4 Is a Sensor for Autophagy Associated with Innate Immunity | Immunity | 2007 | 813 |
| 35 | TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop | Nature Cell Biology | 2013 | 796 |
| 36 | Carotid Intima-Media Thickness and Presence or Absence of Plaque Improves Prediction of Coronary Heart Disease Risk | Journal of the American College of Cardiology | 2010 | 794 |
| 37 | ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions | Blood | 2002 | 777 |
| 38 | Burden of Gastric Cancer | Clinical Gastroenterology and Hepatology | 2020 | 775 |
| 39 | Pathophysiologically Relevant Concentrations of Tumor Necrosis Factor-α Promote Progressive Left Ventricular Dysfunction and Remodeling in Rats | Circulation | 1998 | 773 |
| 40 | Disruption of Splicing Regulated by a CUG-Binding Protein in Myotonic Dystrophy | Science | 1998 | 764 |
| 41 | Mechanisms and Models in Heart Failure | Circulation | 2005 | 740 |
| 42 | Prevalence of Antibiotic Resistance in Helicobacter pylori: A Systematic Review and Meta-analysis in World Health Organization Regions | Gastroenterology | 2018 | 740 |
| 43 | A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum Cardiomyopathy | Cell | 2007 | 736 |
| 44 | Characteristics of Patients with Uncontrolled Hypertension in the United States | New England Journal of Medicine | 2001 | 728 |
| 45 | Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part II: Definition. A Consensus Statement of the International Society for Heart and Lung Transplantation | Journal of Heart and Lung Transplantation | 2005 | 724 |
| 46 | Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo | FASEB Journal | 1990 | 719 |
| 47 | Role of the Estrogen Receptor Coactivator AIB1 (SRC-3) and HER-2/neu in Tamoxifen Resistance in Breast Cancer | Journal of the National Cancer Institute | 2003 | 717 |
| 48 | Mechanisms and Models in Heart Failure | Circulation | 1999 | 706 |
| 49 | Matrilysin Shedding of Syndecan-1 Regulates Chemokine Mobilization and Transepithelial Efflux of Neutrophils in Acute Lung Injury | Cell | 2002 | 706 |
| 50 | Risk of Hepatocellular Cancer in HCV Patients Treated With Direct-Acting Antiviral Agents | Gastroenterology | 2017 | 680 |
