# | Title | Journal | Year | Citations |
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1 | NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review | Frontiers in Molecular Neuroscience | 2015 | 616 |
2 | Electrospun collagen/chitosan nanofibrous membrane as wound dressing | Colloids and Surfaces A: Physicochemical and Engineering Aspects | 2008 | 438 |
3 | Oxidative stress caused by mitochondrial calcium overload | Annals of the New York Academy of Sciences | 2010 | 411 |
4 | Melatonin as a mitochondria-targeted antioxidant: one of evolution’s best ideas | Cellular and Molecular Life Sciences | 2017 | 369 |
5 | Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases | Biochemical Pharmacology | 2012 | 346 |
6 | Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes | Journal of Pineal Research | 2004 | 240 |
7 | Formation of elongated giant mitochondria in DFO-induced cellular senescence: Involvement of enhanced fusion process through modulation of Fis1 | Journal of Cellular Physiology | 2006 | 234 |
8 | Electrospun PLGA/collagen nanofibrous membrane as early-stage wound dressing | Journal of Membrane Science | 2010 | 220 |
9 | Melatonin protects against common deletion of mitochondrial DNA‐augmented mitochondrial oxidative stress and apoptosis | Journal of Pineal Research | 2007 | 217 |
10 | The Emergence of Drug Transporter-Mediated Multidrug Resistance to Cancer Chemotherapy | Molecular Pharmaceutics | 2011 | 199 |
11 | Magnetically targeted thrombolysis with recombinant tissue plasminogen activator bound to polyacrylic acid-coated nanoparticles | Biomaterials | 2009 | 163 |
12 | Characterization of chitosan magnetic nanoparticles for in situ delivery of tissue plasminogen activator | Carbohydrate Polymers | 2011 | 148 |
13 | Visualization of melatonin’s multiple mitochondrial levels of protection against mitochondrial Ca2+‐mediated permeability transition and beyond in rat brain astrocytes | Journal of Pineal Research | 2010 | 145 |
14 | Involvement of p42/p44 MAPK, p38 MAPK, JNK and nuclear factor-kappa B in interleukin-1beta-induced matrix metalloproteinase-9 expression in rat brain astrocytes | Journal of Neurochemistry | 2004 | 132 |
15 | Interleukin-1β induces MMP-9 expression via p42/p44 MAPK, p38 MAPK, JNK, and nuclear factor-κB signaling pathways in human tracheal smooth muscle cells | Journal of Cellular Physiology | 2007 | 121 |
16 | Sustainable release of vancomycin, gentamicin and lidocaine from novel electrospun sandwich-structured PLGA/collagen nanofibrous membranes | International Journal of Pharmaceutics | 2012 | 108 |
17 | Induction of COX-2/PGE2/IL-6 is crucial for cigarette smoke extract-induced airway inflammation: Role of TLR4-dependent NADPH oxidase activation | Free Radical Biology and Medicine | 2010 | 100 |
18 | Novel Dengue Virus-Specific NS2B/NS3 Protease Inhibitor, BP2109, Discovered by a High-Throughput Screening Assay | Antimicrobial Agents and Chemotherapy | 2011 | 100 |
19 | Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells | Cell Communication and Signaling | 2012 | 97 |
20 | Cooperation of TLR2 with MyD88, PI3K, and Rac1 in Lipoteichoic Acid–Induced cPLA2/COX-2–Dependent Airway Inflammatory Responses | American Journal of Pathology | 2010 | 87 |
21 | P2Y2 receptor-mediated proliferation of C6 glioma cells via activation of Ras/Raf/MEK/MAPK pathway | British Journal of Pharmacology | 2000 | 85 |
22 | Japanese encephalitis virus induces matrix metalloproteinase-9 expression via a ROS/c-Src/PDGFR/PI3K/Akt/MAPKs-dependent AP-1 pathway in rat brain astrocytes | Journal of Neuroinflammation | 2012 | 84 |
23 | Enterovirus 71 induces COX-2 expression via MAPKs, NF-κB, and AP-1 in SK–N–SH cells: Role of PGE2 in viral replication | Cellular Signalling | 2010 | 80 |
24 | Cigarette smoke particle-phase extract induces HO-1 expression in human tracheal smooth muscle cells: role of the c-Src/NADPH oxidase/MAPK/Nrf2 signaling pathway | Free Radical Biology and Medicine | 2010 | 80 |
25 | Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats | Journal of Pineal Research | 2010 | 80 |
26 | Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3 | International Journal of Molecular Sciences | 2018 | 80 |
27 | Riluzole and Prognostic Factors in Amyotrophic Lateral Sclerosis Long-term and Short-term Survival: A Population-Based Study of 1149 Cases in Taiwan | Journal of Epidemiology | 2013 | 77 |
28 | Critical role of mitochondrial reactive oxygen species formation in visible laser irradiation-induced apoptosis in rat brain astrocytes (RBA-1) | Journal of Biomedical Science | 2002 | 75 |
29 | Resveratrol inhibits BK-induced COX-2 transcription by suppressing acetylation of AP-1 and NF-κB in human rheumatoid arthritis synovial fibroblasts | Biochemical Pharmacology | 2017 | 75 |
30 | Mitogenic effect of oxidized low-density lipoprotein on vascular smooth muscle cells mediated by activation of Ras/Raf/MEK/MAPK pathway | British Journal of Pharmacology | 2001 | 72 |
31 | Enterovirus 71 induces integrin β1/EGFR-Rac1-dependent oxidative stress in SK-N-SH cells: Role of HO-1/CO in viral replication | Journal of Cellular Physiology | 2011 | 72 |
32 | Protective effects of (−)-epigallocatechin-3-gallate against TNF-α-induced lung inflammation via ROS-dependent ICAM-1 inhibition | Journal of Nutritional Biochemistry | 2013 | 72 |
33 | Intracellular signalings underlying bradykinin-induced matrix metalloproteinase-9 expression in rat brain astrocyte-1 | Cellular Signalling | 2004 | 71 |
34 | BK-induced COX-2 expression via PKC-δ-dependent activation of p42/p44 MAPK and NF-κB in astrocytes | Cellular Signalling | 2007 | 70 |
35 | Overexpression of ATP-binding cassette transporter ABCG2 as a potential mechanism of acquired resistance to vemurafenib in BRAF(V600E) mutant cancer cells | Biochemical Pharmacology | 2013 | 70 |
36 | Interleukin-1β-induced cyclooxygenase-2 expression is mediated through activation of p42/44 and p38 MAPKS, and NF-κB pathways in canine tracheal smooth muscle cells | Cellular Signalling | 2002 | 69 |
37 | Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism | Experimental Neurology | 2015 | 69 |
38 | Sphingosine-1-phosphate induces COX-2 expression via PI3K/Akt and p42/p44 MAPK pathways in rat vascular smooth muscle cells | Journal of Cellular Physiology | 2006 | 67 |
39 | IL‐1β induces MMP‐9 expression via a Ca2+‐dependent CaMKII/JNK/c‐JUN cascade in rat brain astrocytes | Glia | 2009 | 67 |
40 | Involvement of p42/p44 MAPK, JNK, and NF-?B in IL-1?-induced ICAM-1 expression in human pulmonary epithelial cells | Journal of Cellular Physiology | 2005 | 65 |
41 | TNF-α induces matrix metalloproteinase-9-dependent soluble intercellular adhesion molecule-1 release via TRAF2-mediated MAPKs and NF-κB activation in osteoblast-like MC3T3-E1 cells | Journal of Biomedical Science | 2014 | 65 |
42 | Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages | Journal of Clinical Investigation | 2017 | 64 |
43 | The discoveries of molecular mechanisms for the circadian rhythm: The 2017 Nobel Prize in Physiology or Medicine | Biomedical Journal | 2018 | 64 |
44 | Lipopolysaccharide induces VCAM-1 expression and neutrophil adhesion to human tracheal smooth muscle cells: Involvement of Src/EGFR/PI3-K/Akt pathway | Toxicology and Applied Pharmacology | 2008 | 63 |
45 | Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced cyclooxygenase-2 expression in mouse brain endothelial cells | Journal of Neuroinflammation | 2010 | 63 |
46 | Reactive Oxygen Species-Dependent c-Fos/Activator Protein 1 Induction Upregulates Heme Oxygenase-1 Expression by Bradykinin in Brain Astrocytes | Antioxidants and Redox Signaling | 2010 | 63 |
47 | Lipopolysaccharide induces ICAM-1 expression via a c-Src/NADPH oxidase/ROS-dependent NF-κB pathway in human pulmonary alveolar epithelial cells | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2016 | 63 |
48 | Mitochondrial Reactive Oxygen Species Generation and Calcium Increase Induced by Visible Light in Astrocytes | Annals of the New York Academy of Sciences | 2004 | 61 |
49 | PKC-δ/c-Src-mediated EGF receptor transactivation regulates thrombin-induced COX-2 expression and PGE2 production in rat vascular smooth muscle cells | Biochimica Et Biophysica Acta - Molecular Cell Research | 2008 | 61 |
50 | NADPH oxidase 2-derived reactive oxygen species signal contributes to bradykinin-induced matrix metalloproteinase-9 expression and cell migration in brain astrocytes | Cell Communication and Signaling | 2012 | 61 |