| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota | Nature Communications | 2015 | 926 |
| 3 | SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses | Cell | 2022 | 788 |
| 4 | Granulysin is a key mediator for disseminated keratinocyte death in Stevens-Johnson syndrome and toxic epidermal necrolysis | Nature Medicine | 2008 | 653 |
| 5 | NF-kappaB Signaling Pathways in Neurological Inflammation: A Mini Review | Frontiers in Molecular Neuroscience | 2015 | 616 |
| 6 | Gut commensal Parabacteroides goldsteinii plays a predominant role in the anti-obesity effects of polysaccharides isolated from Hirsutella sinensis | Gut | 2019 | 524 |
| 7 | The Novel Coronavirus 2019 epidemic and kidneys | Kidney International | 2020 | 502 |
| 8 | Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome | Nature Biotechnology | 2012 | 461 |
| 9 | Tissue macrophages: heterogeneity and functions | BMC Biology | 2017 | 448 |
| 10 | Oxidative stress caused by mitochondrial calcium overload | Annals of the New York Academy of Sciences | 2010 | 411 |
| 11 | Clinical features and risk factors of pulmonary oedema after enterovirus-71-related hand, foot, and mouth disease | Lancet, The | 1999 | 386 |
| 12 | Melatonin as a mitochondria-targeted antioxidant: one of evolution’s best ideas | Cellular and Molecular Life Sciences | 2017 | 369 |
| 13 | Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases | Biochemical Pharmacology | 2012 | 346 |
| 14 | Myopia Prevention and Outdoor Light Intensity in a School-Based Cluster Randomized Trial | Ophthalmology | 2018 | 337 |
| 15 | Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats | American Journal of Physiology - Endocrinology and Metabolism | 2006 | 328 |
| 16 | GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy | Science | 2012 | 320 |
| 17 | New epidemiology of Staphylococcus aureus infection in Asia | Clinical Microbiology and Infection | 2014 | 317 |
| 18 | Common risk allele in aromatic antiepileptic-drug induced Stevens–Johnson syndrome and toxic epidermal necrolysis in Han Chinese | Pharmacogenomics | 2010 | 277 |
| 19 | A novel approach to the treatment of lower extremity lymphedema by transferring a vascularized submental lymph node flap to the ankle | Gynecologic Oncology | 2012 | 271 |
| 20 | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient | Nature Structural and Molecular Biology | 2020 | 268 |
| 21 | Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome | Journal of Allergy and Clinical Immunology | 2012 | 262 |
| 22 | A mitochondrial superoxide theory for oxidative stress diseases and aging | Journal of Clinical Biochemistry and Nutrition | 2015 | 253 |
| 23 | Intraductal papillary neoplasia of the liver associated with hepatolithiasis | Hepatology | 2001 | 252 |
| 24 | Probiotics, prebiotics and amelioration of diseases | Journal of Biomedical Science | 2019 | 242 |
| 25 | Evaluating 3D‐Printed Biomaterials as Scaffolds for Vascularized Bone Tissue Engineering | Advanced Materials | 2015 | 241 |
| 26 | Control of the negative IREStrans-acting factor KHSRP by ubiquitination | Nucleic Acids Research | 2017 | 231 |
| 27 | Mechanisms of acquired resistance to first-line osimertinib: Preliminary data from the phase III FLAURA study | Annals of Oncology | 2018 | 229 |
| 28 | Molecular Signatures of Major Depression | Current Biology | 2015 | 224 |
| 29 | Evidence‐based (S3) Guideline on (anogenital) Lichen sclerosus | Journal of the European Academy of Dermatology and Venereology | 2015 | 223 |
| 30 | Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity | Nature Immunology | 2015 | 218 |
| 31 | Melatonin protects against common deletion of mitochondrial DNA‐augmented mitochondrial oxidative stress and apoptosis | Journal of Pineal Research | 2007 | 217 |
| 32 | Effects of Maternal Screening and Universal Immunization to Prevent Mother-to-Infant Transmission of HBV | Gastroenterology | 2012 | 212 |
| 33 | Next generation probiotics in disease amelioration | Journal of Food and Drug Analysis | 2019 | 212 |
| 34 | Oral Microbiota Community Dynamics Associated With Oral Squamous Cell Carcinoma Staging | Frontiers in Microbiology | 2018 | 211 |
| 35 | Functional Network Analysis of the Transcriptomes of Mesenchymal Stem Cells Derived from Amniotic Fluid, Amniotic Membrane, Cord Blood, and Bone Marrow | Stem Cells | 2007 | 209 |
| 36 | Donor Site Morbidity after Suprafascial Elevation of the Radial Forearm Flap: A Prospective Study in 95 Consecutive Cases | Plastic and Reconstructive Surgery | 1999 | 206 |
| 37 | Nontyphoid Salmonella Infection: Microbiology, Clinical Features, and Antimicrobial Therapy | Pediatrics and Neonatology | 2013 | 206 |
| 38 | A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses | Nature Communications | 2021 | 200 |
| 39 | Academic outcomes of flipped classroom learning: a meta-analysis | Medical Education | 2018 | 197 |
| 40 | Off-therapy durability of response to entecavir therapy in hepatitis B e antigen-negative chronic hepatitis B patients | Hepatology | 2013 | 196 |
| 41 | Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis | Nature Cell Biology | 2010 | 190 |
| 42 | High-purity and label-free isolation of circulating tumor cells (CTCs) in a microfluidic platform by using optically-induced-dielectrophoretic (ODEP) force | Lab on A Chip | 2013 | 187 |
| 43 | Baseline characteristics and early on-treatment response predict the outcomes of 2years of telbivudine treatment of chronic hepatitis B | Journal of Hepatology | 2009 | 185 |
| 44 | Comparative and Targeted Proteomic Analyses of Urinary Microparticles from Bladder Cancer and Hernia Patients | Journal of Proteome Research | 2012 | 185 |
| 45 | Randomized, controlled trial of TNF-α antagonist in CTL-mediated severe cutaneous adverse reactions | Journal of Clinical Investigation | 2018 | 185 |
| 46 | ER stress, autophagy, and RNA viruses | Frontiers in Microbiology | 2014 | 184 |
| 47 | Polyphenols and Oxidative Stress in Atherosclerosis-Related Ischemic Heart Disease and Stroke | Oxidative Medicine and Cellular Longevity | 2017 | 179 |
| 48 | Toxic Dimethylarginines: Asymmetric Dimethylarginine (ADMA) and Symmetric Dimethylarginine (SDMA) | Toxins | 2017 | 178 |
| 49 | SARS-CoV-2 Variants, Vaccines, and Host Immunity | Frontiers in Immunology | 2021 | 176 |
| 50 | Osteogenic potential: Comparison between bone marrow and adipose-derived mesenchymal stem cells | World Journal of Stem Cells | 2014 | 174 |
