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exaly
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Department of Biophysics
›
top-articles
Department of Biophysics
339
(top 1%)
papers
23.6K
(top 1%)
citations
74
(top 1%)
h
-index
147
(top 0.1%)
g
-index
417
all documents
29.8K
doc citations
2.2K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Biomolecular condensates: organizers of cellular biochemistry
Nature Reviews Molecular Cell Biology
2017
3,771
2
Accurate prediction of protein structures and interactions using a three-track neural network
Science
2021
2,843
3
Compositional Control of Phase-Separated Cellular Bodies
Cell
2016
945
4
Organization of Chromatin by Intrinsic and Regulated Phase Separation
Cell
2019
707
5
Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein
Molecular Cell
2016
622
6
Structural basis of STING binding with and phosphorylation by TBK1
Nature
2019
540
7
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
ELife
2017
514
8
Phase transitions of multivalent proteins can promote clustering of membrane receptors
ELife
2014
463
9
A framework for understanding the functions of biomolecular condensates across scales
Nature Reviews Molecular Cell Biology
2021
450
10
Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
Nature
2019
392
11
Microtubule dynamics: an interplay of biochemistry and mechanics
Nature Reviews Molecular Cell Biology
2018
379
12
Atypical angiopoietin-like protein that regulates ANGPTL3
Proceedings of the National Academy of Sciences of the United States of America
2012
375
13
The Membrane Fusion Enigma: SNAREs, Sec1/Munc18 Proteins, and Their Accomplices—Guilty as Charged?
Annual Review of Cell and Developmental Biology
2012
363
14
Stoichiometry controls activity of phase-separated clusters of actin signaling proteins
Science
2019
360
15
Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release
Science
2013
351
16
The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
Cell Reports
2014
351
17
Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway
Immunity
2020
325
18
An optogenetic gene expression system with rapid activation and deactivation kinetics
Nature Chemical Biology
2014
317
19
Computed structures of core eukaryotic protein complexes
Science
2021
316
20
Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs
Journal of Biological Chemistry
2017
288
21
Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting
Molecular Cell
2013
285
22
The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton
Cell
2014
260
23
Intrinsically Disordered Regions Can Contribute Promiscuous Interactions to RNP Granule Assembly
Cell Reports
2018
256
24
Who's In and Who's Out—Compositional Control of Biomolecular Condensates
Journal of Molecular Biology
2018
255
25
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
Science Translational Medicine
2015
254
26
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
Cell
2018
253
27
Structure of mammalian endolysosomal TRPML1 channel in nanodiscs
Nature
2017
244
28
Crystal structure of the human sterol transporter ABCG5/ABCG8
Nature
2016
233
29
Large-scale determination of previously unsolved protein structures using evolutionary information
ELife
2015
229
30
A TOG:αβ-tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase
Science
2012
226
31
Regulation of Transmembrane Signaling by Phase Separation
Annual Review of Biophysics
2019
213
32
Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy
Molecular Biology of the Cell
2015
207
33
Regulation of WASH-Dependent Actin Polymerization and Protein Trafficking by Ubiquitination
Cell
2013
201
34
In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C
Proceedings of the National Academy of Sciences of the United States of America
2014
193
35
Cryo-EM structure of the human cohesin-NIPBL-DNA complex
Science
2020
171
36
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
Cell
2018
170
37
Structural and functional diversity calls for a new classification of ABC transporters
FEBS Letters
2020
169
38
Marker for type VI secretion system effectors
Proceedings of the National Academy of Sciences of the United States of America
2014
165
39
Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation
Current Biology
2014
162
40
Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck
Proceedings of the National Academy of Sciences of the United States of America
2015
162
41
Organization and Function of Non-dynamic Biomolecular Condensates
Trends in Biochemical Sciences
2018
160
42
Structures of the calcium-activated, non-selective cation channel TRPM4
Nature
2017
158
43
Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel
Nature
2018
153
44
Protein AMPylation by an Evolutionarily Conserved Pseudokinase
Cell
2018
149
45
Mechanistic dissection of increased enzymatic rate in a phase-separated compartment
Nature Chemical Biology
2021
149
46
Structure and gating mechanism of the α7 nicotinic acetylcholine receptor
Cell
2021
137
47
Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion
Nature Structural and Molecular Biology
2014
131
48
Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution
Nature Structural and Molecular Biology
2015
129
49
Rac1 GTPase activates the WAVE regulatory complex through two distinct binding sites
ELife
2017
129
50
Local F-actin Network Links Synapse Formation and Axon Branching
Cell
2014
128
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