# | Title | Journal | Year | Citations |
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1 | A restricted cell population propagates glioblastoma growth after chemotherapy | Nature | 2012 | 1,932 |
2 | Hedgehog Signaling in Development and Cancer | Developmental Cell | 2008 | 986 |
3 | White Fat Progenitor Cells Reside in the Adipose Vasculature | Science | 2008 | 983 |
4 | A STING-activating nanovaccine for cancer immunotherapy | Nature Nanotechnology | 2017 | 649 |
5 | Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model | Cancer Cell | 2009 | 612 |
6 | TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive Treatment | Neuron | 2008 | 549 |
7 | The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size Control | Developmental Cell | 2008 | 547 |
8 | Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells | Cell | 2012 | 528 |
9 | HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction | Nature Neuroscience | 2009 | 517 |
10 | MicroRNA-Mediated Control of Oligodendrocyte Differentiation | Neuron | 2010 | 437 |
11 | The paraventricular thalamus controls a central amygdala fear circuit | Nature | 2015 | 416 |
12 | Neurofibromin Regulation of ERK Signaling Modulates GABA Release and Learning | Cell | 2008 | 384 |
13 | Regulation of TFEB and V-ATPases by mTORC1 | EMBO Journal | 2011 | 379 |
14 | Mesp1 Acts as a Master Regulator of Multipotent Cardiovascular Progenitor Specification | Cell Stem Cell | 2008 | 341 |
15 | Isolation and culture of rat and mouse oligodendrocyte precursor cells | Nature Protocols | 2007 | 340 |
16 | Nf1-Dependent Tumors Require a Microenvironment Containing Nf1+/−- and c-kit-Dependent Bone Marrow | Cell | 2008 | 325 |
17 | Functional skeletal muscle regeneration from differentiating embryonic stem cells | Nature Medicine | 2008 | 308 |
18 | Olig2 Targets Chromatin Remodelers to Enhancers to Initiate Oligodendrocyte Differentiation | Cell | 2013 | 307 |
19 | ER71 Acts Downstream of BMP, Notch, and Wnt Signaling in Blood and Vessel Progenitor Specification | Cell Stem Cell | 2008 | 294 |
20 | Hippo signaling regulatesDrosophilaintestine stem cell proliferation through multiple pathways | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 283 |
21 | The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelination | Nature Neuroscience | 2009 | 277 |
22 | Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 274 |
23 | Hedgehog regulates smoothened activity by inducing a conformational switch | Nature | 2007 | 244 |
24 | Caspase Activity Mediates the Differentiation of Embryonic Stem Cells | Cell Stem Cell | 2008 | 244 |
25 | Pten Haploinsufficiency Accelerates Formation of High-Grade Astrocytomas | Cancer Research | 2008 | 243 |
26 | The developmental origins of adipose tissue | Development (Cambridge) | 2013 | 241 |
27 | Atf4 Regulates Obesity, Glucose Homeostasis, and Energy Expenditure | Diabetes | 2009 | 206 |
28 | The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis | Molecular Metabolism | 2013 | 202 |
29 | Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 196 |
30 | Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial | Lancet Oncology, The | 2012 | 195 |
31 | Epithelial dynamics of pancreatic branching morphogenesis | Development (Cambridge) | 2010 | 192 |
32 | Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 179 |
33 | Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened | PLoS Biology | 2011 | 176 |
34 | Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes | Cancer Cell | 2015 | 171 |
35 | A crucial role for Olig2 in white matter astrocyte development | Development (Cambridge) | 2007 | 170 |
36 | Inducible Cassette Exchange: A Rapid and Efficient System Enabling Conditional Gene Expression in Embryonic Stem and Primary Cells | Stem Cells | 2011 | 170 |
37 | PTEN signaling in autism spectrum disorders | Current Opinion in Neurobiology | 2012 | 167 |
38 | Adenosine Nucleotide Biosynthesis and AMPK Regulate Adult Life Span and Mediate the Longevity Benefit of Caloric Restriction in Flies | Cell Metabolism | 2013 | 167 |
39 | HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination | Nature Neuroscience | 2011 | 165 |
40 | Cell of Origin for Malignant Gliomas and Its Implication in Therapeutic Development | Cold Spring Harbor Perspectives in Biology | 2015 | 163 |
41 | Biphasic and Dosage-Dependent Regulation of Osteoclastogenesis by β-Catenin | Molecular and Cellular Biology | 2011 | 161 |
42 | A Validated Tumorgraft Model Reveals Activity of Dovitinib Against Renal Cell Carcinoma | Science Translational Medicine | 2012 | 159 |
43 | Dissociation of EphB2 Signaling Pathways Mediating Progenitor Cell Proliferation and Tumor Suppression | Cell | 2009 | 157 |
44 | Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanisms | Developmental Biology | 2010 | 156 |
45 | PtenDeletion in Adult Hippocampal Neural Stem/Progenitor Cells Causes Cellular Abnormalities and Alters Neurogenesis | Journal of Neuroscience | 2012 | 154 |
46 | Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization | Science Signaling | 2012 | 143 |
47 | Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein Sip1 Is Required for Myelination in the Central Nervous System | Neuron | 2012 | 140 |
48 | CXCR4/CXCL12 Mediate Autocrine Cell- Cycle Progression in NF1-Associated Malignant Peripheral Nerve Sheath Tumors | Cell | 2013 | 139 |
49 | Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning | Nature Neuroscience | 2009 | 138 |
50 | Hedgehog-Regulated Ubiquitination Controls Smoothened Trafficking and Cell Surface Expression in Drosophila | PLoS Biology | 2012 | 129 |