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Top Articles

#TitleJournalYearCitations
1A restricted cell population propagates glioblastoma growth after chemotherapyNature20121,932
2Hedgehog Signaling in Development and CancerDevelopmental Cell2008986
3White Fat Progenitor Cells Reside in the Adipose VasculatureScience2008983
4A STING-activating nanovaccine for cancer immunotherapyNature Nanotechnology2017649
5Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse ModelCancer Cell2009612
6TrkB Regulates Hippocampal Neurogenesis and Governs Sensitivity to Antidepressive TreatmentNeuron2008549
7The TEAD/TEF Family of Transcription Factor Scalloped Mediates Hippo Signaling in Organ Size ControlDevelopmental Cell2008547
8Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem CellsCell2012528
9HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interactionNature Neuroscience2009517
10MicroRNA-Mediated Control of Oligodendrocyte DifferentiationNeuron2010437
11The paraventricular thalamus controls a central amygdala fear circuitNature2015416
12Neurofibromin Regulation of ERK Signaling Modulates GABA Release and LearningCell2008384
13Regulation of TFEB and V-ATPases by mTORC1EMBO Journal2011379
14Mesp1 Acts as a Master Regulator of Multipotent Cardiovascular Progenitor SpecificationCell Stem Cell2008341
15Isolation and culture of rat and mouse oligodendrocyte precursor cellsNature Protocols2007340
16Nf1-Dependent Tumors Require a Microenvironment Containing Nf1+/−- and c-kit-Dependent Bone MarrowCell2008325
17Functional skeletal muscle regeneration from differentiating embryonic stem cellsNature Medicine2008308
18Olig2 Targets Chromatin Remodelers to Enhancers to Initiate Oligodendrocyte DifferentiationCell2013307
19ER71 Acts Downstream of BMP, Notch, and Wnt Signaling in Blood and Vessel Progenitor SpecificationCell Stem Cell2008294
20Hippo signaling regulatesDrosophilaintestine stem cell proliferation through multiple pathwaysProceedings of the National Academy of Sciences of the United States of America2010283
21The oligodendrocyte-specific G protein–coupled receptor GPR17 is a cell-intrinsic timer of myelinationNature Neuroscience2009277
22Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockadeProceedings of the National Academy of Sciences of the United States of America2009274
23Hedgehog regulates smoothened activity by inducing a conformational switchNature2007244
24Caspase Activity Mediates the Differentiation of Embryonic Stem CellsCell Stem Cell2008244
25Pten Haploinsufficiency Accelerates Formation of High-Grade AstrocytomasCancer Research2008243
26The developmental origins of adipose tissueDevelopment (Cambridge)2013241
27Atf4 Regulates Obesity, Glucose Homeostasis, and Energy ExpenditureDiabetes2009206
28The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosisMolecular Metabolism2013202
29Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelinationProceedings of the National Academy of Sciences of the United States of America2012196
30Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trialLancet Oncology, The2012195
31Epithelial dynamics of pancreatic branching morphogenesisDevelopment (Cambridge)2010192
32Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelinationProceedings of the National Academy of Sciences of the United States of America2009179
33Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of SmoothenedPLoS Biology2011176
34Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma SubtypesCancer Cell2015171
35A crucial role for Olig2 in white matter astrocyte developmentDevelopment (Cambridge)2007170
36Inducible Cassette Exchange: A Rapid and Efficient System Enabling Conditional Gene Expression in Embryonic Stem and Primary CellsStem Cells2011170
37PTEN signaling in autism spectrum disordersCurrent Opinion in Neurobiology2012167
38Adenosine Nucleotide Biosynthesis and AMPK Regulate Adult Life Span and Mediate the Longevity Benefit of Caloric Restriction in FliesCell Metabolism2013167
39HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelinationNature Neuroscience2011165
40Cell of Origin for Malignant Gliomas and Its Implication in Therapeutic DevelopmentCold Spring Harbor Perspectives in Biology2015163
41Biphasic and Dosage-Dependent Regulation of Osteoclastogenesis by β-CateninMolecular and Cellular Biology2011161
42A Validated Tumorgraft Model Reveals Activity of Dovitinib Against Renal Cell CarcinomaScience Translational Medicine2012159
43Dissociation of EphB2 Signaling Pathways Mediating Progenitor Cell Proliferation and Tumor SuppressionCell2009157
44Hippo signaling regulates Yorkie nuclear localization and activity through 14-3-3 dependent and independent mechanismsDevelopmental Biology2010156
45PtenDeletion in Adult Hippocampal Neural Stem/Progenitor Cells Causes Cellular Abnormalities and Alters NeurogenesisJournal of Neuroscience2012154
46Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced DimerizationScience Signaling2012143
47Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein Sip1 Is Required for Myelination in the Central Nervous SystemNeuron2012140
48CXCR4/CXCL12 Mediate Autocrine Cell- Cycle Progression in NF1-Associated Malignant Peripheral Nerve Sheath TumorsCell2013139
49Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruningNature Neuroscience2009138
50Hedgehog-Regulated Ubiquitination Controls Smoothened Trafficking and Cell Surface Expression in DrosophilaPLoS Biology2012129