| # | Title | Journal | Year | Citations |
|---|
| 1 | New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk | Nature Genetics | 2010 | 1,982 |
| 2 | Metabolic Syndrome Pandemic | Arteriosclerosis, Thrombosis, and Vascular Biology | 2008 | 1,202 |
| 3 | Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions | JAMA - Journal of the American Medical Association | 2016 | 974 |
| 4 | Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI | Molecular and Cellular Biology | 2009 | 862 |
| 5 | Acquired and Inherited Lipodystrophies | New England Journal of Medicine | 2004 | 811 |
| 6 | HMG-CoA Reductase Inhibitors for Treatment of Hypercholesterolemia | New England Journal of Medicine | 1988 | 762 |
| 7 | Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease | Gastroenterology | 2014 | 741 |
| 8 | Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 645 |
| 9 | Race and Gender Differences in C-Reactive Protein Levels | Journal of the American College of Cardiology | 2005 | 618 |
| 10 | Meta-analysis and imputation refines the association of 15q25 with smoking quantity | Nature Genetics | 2010 | 581 |
| 11 | Primary Prevention of Cardiovascular Diseases in People With Diabetes Mellitus: A scientific statement from the American Heart Association and the American Diabetes Association | Diabetes Care | 2007 | 577 |
| 12 | Metabolic Syndrome: A Multiplex Cardiovascular Risk Factor | Journal of Clinical Endocrinology and Metabolism | 2007 | 566 |
| 13 | Effect of Lowering LDL Cholesterol Substantially Below Currently Recommended Levels in Patients With Coronary Heart Disease and Diabetes: The Treating to New Targets (TNT) study | Diabetes Care | 2006 | 493 |
| 14 | Hypertriglyceridemia, Atherogenic Dyslipidemia, and the Metabolic Syndrome | American Journal of Cardiology | 1998 | 451 |
| 15 | Lipodystrophies: Genetic and Acquired Body Fat Disorders | Journal of Clinical Endocrinology and Metabolism | 2011 | 434 |
| 16 | Comparison of a High-Carbohydrate Diet with a High-Monounsaturated-Fat Diet in Patients with Non-Insulin-Dependent Diabetes Mellitus | New England Journal of Medicine | 1988 | 383 |
| 17 | Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice | Nature | 2018 | 359 |
| 18 | Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults | Obesity | 2013 | 355 |
| 19 | The Effect of α-Tocopherol Supplementation on LDL Oxidation | Arteriosclerosis, Thrombosis, and Vascular Biology | 1995 | 338 |
| 20 | LDL-cholesterol concentrations: a genome-wide association study | Lancet, The | 2008 | 329 |
| 21 | Serum Adiponectin and Leptin Levels in Patients with Lipodystrophies | Journal of Clinical Endocrinology and Metabolism | 2002 | 307 |
| 22 | PSMB8 Encoding the β5i Proteasome Subunit Is Mutated in Joint Contractures, Muscle Atrophy, Microcytic Anemia, and Panniculitis-Induced Lipodystrophy Syndrome | American Journal of Human Genetics | 2010 | 305 |
| 23 | Multifactorial causation of obesity: implications for prevention | American Journal of Clinical Nutrition | 1998 | 286 |
| 24 | Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein | Atherosclerosis | 1990 | 274 |
| 25 | Influence of Body Fat Content and Distribution on Variation in Metabolic Risk | Journal of Clinical Endocrinology and Metabolism | 2006 | 270 |
| 26 | Relationship of Generalized and Regional Adiposity to Insulin Sensitivity in Men With NIDDM | Diabetes | 1996 | 265 |
| 27 | Management of Dyslipidemia in NIDDM | Diabetes Care | 1990 | 260 |
| 28 | Niche-Specific Reprogramming of Epigenetic Landscapes Drives Myeloid Cell Diversity in Nonalcoholic Steatohepatitis | Immunity | 2020 | 248 |
| 29 | Dietary Sugars Stimulate Fatty Acid Synthesis in Adults3 | Journal of Nutrition | 2008 | 237 |
| 30 | Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC | EMBO Molecular Medicine | 2009 | 235 |
| 31 | Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity | Immunity | 2019 | 234 |
| 32 | Contributions of Different Fatty Acid Sources to Very Low-Density Lipoprotein-Triacylglycerol in the Fasted and Fed States | Journal of Clinical Endocrinology and Metabolism | 2006 | 221 |
| 33 | Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy | Cell Metabolism | 2009 | 206 |
| 34 | Primary Prevention of Coronary Heart Disease | Circulation | 1999 | 204 |
| 35 | β-Carotene inhibits the oxidative modification of low-density lipoprotein | Lipids and Lipid Metabolism | 1991 | 201 |
| 36 | Effect of dietary supplementation with alpha-tocopherol on the oxidative modification of low density lipoprotein | Journal of Lipid Research | 1992 | 199 |
| 37 | Congenital generalized lipodystrophies—new insights into metabolic dysfunction | Nature Reviews Endocrinology | 2015 | 195 |
| 38 | Insulin Resistance and Body Fat Distribution in South Asian Men Compared to Caucasian Men | PLoS ONE | 2007 | 190 |
| 39 | FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia | Cell Metabolism | 2017 | 184 |
| 40 | Relationship of Anterior and Posterior Subcutaneous Abdominal Fat to Insulin Sensitivity in Nondiabetic Men | Obesity | 1997 | 178 |
| 41 | Triglyceride–to–High-Density-Lipoprotein-Cholesterol Ratio is an Index of Heart Disease Mortality and of Incidence of Type 2 Diabetes Mellitus in Men | Journal of Investigative Medicine | 2014 | 178 |
| 42 | Effect of combined supplementation with alpha-tocopherol, ascorbate, and beta carotene on low-density lipoprotein oxidation. | Circulation | 1993 | 174 |
| 43 | Metabolic Complications of Obesity | Endocrine | 2000 | 174 |
| 44 | Adipose Tissue Distribution Pattern in Patients with Familial Partial Lipodystrophy (Dunnigan Variety)1 | Journal of Clinical Endocrinology and Metabolism | 1999 | 173 |
| 45 | Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia | Circulation | 2019 | 170 |
| 46 | Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21. | Journal of Clinical Investigation | 1998 | 169 |
| 47 | Sex Steroid Hormones, Upper Body Obesity, and Insulin Resistance | Journal of Clinical Endocrinology and Metabolism | 2002 | 167 |
| 48 | Regional Adiposity and Insulin Resistance | Journal of Clinical Endocrinology and Metabolism | 2004 | 167 |
| 49 | AMPK: Potential Therapeutic Target for Ischemic Stroke | Theranostics | 2018 | 159 |
| 50 | Phenotypic Heterogeneity in Body Fat Distribution in Patients with Congenital Generalized Lipodystrophy Caused by Mutations in the AGPAT2 or Seipin Genes | Journal of Clinical Endocrinology and Metabolism | 2003 | 155 |
