| # | Title | Journal | Year | Citations |
|---|
| 1 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 2 | Consensus statement on the pathology of IgG4-related disease | Modern Pathology | 2012 | 2,171 |
| 3 | Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer | Nature Medicine | 2004 | 1,852 |
| 4 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,789 |
| 5 | ACG Clinical Guideline: Ulcerative Colitis in Adults | American Journal of Gastroenterology | 2019 | 933 |
| 6 | Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution | Nature Genetics | 2010 | 836 |
| 7 | Vaccine side-effects and SARS-CoV-2 infection after vaccination in users of the COVID Symptom Study app in the UK: a prospective observational study | Lancet Infectious Diseases, The | 2021 | 744 |
| 8 | Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma | Cell Reports | 2016 | 671 |
| 9 | Relating the metatranscriptome and metagenome of the human gut | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 552 |
| 10 | A Prospective Study of Long-term Intake of Dietary Fiber and Risk of Crohn's Disease and Ulcerative Colitis | Gastroenterology | 2013 | 494 |
| 11 | Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality | JAMA Internal Medicine | 2016 | 486 |
| 12 | Influence of the Gut Microbiome, Diet, and Environment on Risk of Colorectal Cancer | Gastroenterology | 2020 | 408 |
| 13 | Long-term intake of dietary fat and risk of ulcerative colitis and Crohn's disease | Gut | 2014 | 386 |
| 14 | Discovery of common and rare genetic risk variants for colorectal cancer | Nature Genetics | 2019 | 377 |
| 15 | Aspirin and colorectal cancer: the promise of precision chemoprevention | Nature Reviews Cancer | 2016 | 370 |
| 16 | Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease | Science | 2017 | 367 |
| 17 | Comprehensive serological profiling of human populations using a synthetic human virome | Science | 2015 | 364 |
| 18 | De novo design of potent and selective mimics of IL-2 and IL-15 | Nature | 2019 | 362 |
| 19 | Higher Predicted Vitamin D Status Is Associated With Reduced Risk of Crohn's Disease | Gastroenterology | 2012 | 361 |
| 20 | Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation | PLoS Medicine | 2013 | 354 |
| 21 | The complex link between NAFLD and type 2 diabetes mellitus — mechanisms and treatments | Nature Reviews Gastroenterology and Hepatology | 2021 | 346 |
| 22 | Trends in Sedentary Behavior Among the US Population, 2001-2016 | JAMA - Journal of the American Medical Association | 2019 | 327 |
| 23 | Complex host genetics influence the microbiome in inflammatory bowel disease | Genome Medicine | 2014 | 322 |
| 24 | Gut Microbiome Function Predicts Response to Anti-integrin Biologic Therapy in Inflammatory Bowel Diseases | Cell Host and Microbe | 2017 | 306 |
| 25 | Association of Obesity With Risk of Early-Onset Colorectal Cancer Among Women | JAMA Oncology | 2019 | 305 |
| 26 | Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis | Cancer Cell | 2019 | 278 |
| 27 | AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease: Expert Review | Gastroenterology | 2021 | 245 |
| 28 | Prognosis of invasive intraductal papillary mucinous neoplasm depends on histological and precursor epithelial subtypes | Gut | 2011 | 244 |
| 29 | Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue | JAMA Oncology | 2017 | 243 |
| 30 | Aspirin in the Chemoprevention of Colorectal Neoplasia: An Overview | Cancer Prevention Research | 2012 | 242 |
| 31 | Pathways of Colorectal Carcinogenesis | Gastroenterology | 2020 | 241 |
| 32 | Plasmacytoid Dendritic Cells Mediate Anti-inflammatory Responses to a Gut Commensal Molecule via Both Innate and Adaptive Mechanisms | Cell Host and Microbe | 2014 | 239 |
| 33 | Non-alcoholic fatty liver disease and risk of fatal and non-fatal cardiovascular events: an updated systematic review and meta-analysis | The Lancet Gastroenterology and Hepatology | 2021 | 227 |
| 34 | Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors | Gastroenterology | 2018 | 226 |
| 35 | Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk | Nature Genetics | 2014 | 212 |
| 36 | Nanobody-based CAR T cells that target the tumor microenvironment inhibit the growth of solid tumors in immunocompetent mice | Proceedings of the National Academy of Sciences of the United States of America | 2019 | 205 |
| 37 | Statistical methods for studying disease subtype heterogeneity | Statistics in Medicine | 2016 | 204 |
| 38 | Environmental Factors, Gut Microbiota, and Colorectal Cancer Prevention | Clinical Gastroenterology and Hepatology | 2019 | 194 |
| 39 | Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease | Modern Pathology | 2013 | 193 |
| 40 | Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis | Nature Communications | 2020 | 193 |
| 41 | Sleep Disturbance and Risk of Active Disease in Patients With Crohn's Disease and Ulcerative Colitis | Clinical Gastroenterology and Hepatology | 2013 | 192 |
| 42 | A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers | Nature Communications | 2018 | 192 |
| 43 | A Prospective Study of Cigarette Smoking and the Risk of Inflammatory Bowel Disease in Women | American Journal of Gastroenterology | 2012 | 191 |
| 44 | Geographical variation and incidence of inflammatory bowel disease among US women | Gut | 2012 | 187 |
| 45 | Meta-analysis of new genome-wide association studies of colorectal cancer risk | Human Genetics | 2012 | 183 |
| 46 | Standardized terminology and nomenclature for pancreatobiliary cytology: The Papanicolaou Society of Cytopathology guidelines | Diagnostic Cytopathology | 2014 | 181 |
| 47 | Review article: vitamin D and inflammatory bowel diseases | Alimentary Pharmacology and Therapeutics | 2014 | 181 |
| 48 | Adverse Events Following Cancer Immunotherapy: Obstacles and Opportunities | Trends in Immunology | 2019 | 180 |
| 49 | The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk | Nature Medicine | 2021 | 179 |
| 50 | The role of diet in the aetiopathogenesis of inflammatory bowel disease | Nature Reviews Gastroenterology and Hepatology | 2018 | 178 |
