| # | Title | Journal | Year | Citations |
|---|
| 1 | Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules | Trends in Pharmacological Sciences | 2008 | 366 |
| 2 | The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane | Kidney International | 2008 | 233 |
| 3 | Usage patterns of personal care products: Important factors for exposure assessment | Food and Chemical Toxicology | 2013 | 169 |
| 4 | Novel conditionally immortalized human proximal tubule cell line expressing functional influx and efflux transporters | Cell and Tissue Research | 2010 | 167 |
| 5 | Cysteamine: an old drug with new potential | Drug Discovery Today | 2013 | 156 |
| 6 | The Role of ATP Binding Cassette Transporters in Tissue Defense and Organ Regeneration | Journal of Pharmacology and Experimental Therapeutics | 2009 | 154 |
| 7 | Ischemic Preconditioning in the Animal Kidney, a Systematic Review and Meta-Analysis | PLoS ONE | 2012 | 151 |
| 8 | Multidrug Resistance Protein 4 (MRP4/ABCC4) Regulates cAMP Cellular Levels and Controls Human Leukemia Cell Proliferation and Differentiation | Journal of Biological Chemistry | 2011 | 142 |
| 9 | Contribution of Multidrug Resistance Protein 2 (MRP2/ABCC2) to the Renal Excretion of p-aminohippurate (PAH) and Identification of MRP4 (ABCC4) as a Novel PAH Transporter | Journal of the American Society of Nephrology: JASN | 2004 | 140 |
| 10 | Alkaline phosphatase treatment improves renal function in severe sepsis or septic shock patients* | Critical Care Medicine | 2009 | 140 |
| 11 | Trends in use and misuse of opioids in the Netherlands: a retrospective, multi-source database study | Lancet Public Health, The | 2019 | 134 |
| 12 | Haematopoietic stem cells and endothelial progenitor cells in healthy men: effect of aging and training | Aging Cell | 2006 | 132 |
| 13 | Iron metabolism in the pathogenesis of iron-induced kidney injury | Nature Reviews Nephrology | 2013 | 126 |
| 14 | Uremic Toxins Inhibit Transport by Breast Cancer Resistance Protein and Multidrug Resistance Protein 4 at Clinically Relevant Concentrations | PLoS ONE | 2011 | 113 |
| 15 | The role of reactive oxygen species in apoptosis of the diabetic kidney | Apoptosis: an International Journal on Programmed Cell Death | 2009 | 110 |
| 16 | Vildagliptin Improves Endothelium-Dependent Vasodilatation in Type 2 Diabetes | Diabetes Care | 2011 | 108 |
| 17 | Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2013 | 105 |
| 18 | Mechanisms of renal anionic drug transport | European Journal of Pharmacology | 2008 | 104 |
| 19 | Curcumin‐induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation | Journal of Cellular and Molecular Medicine | 2009 | 96 |
| 20 | Endocrine Disruptors Differentially Target ATP-Binding Cassette Transporters in the Blood-Testis Barrier and Affect Leydig Cell Testosterone Secretion In Vitro | Toxicological Sciences | 2013 | 96 |
| 21 | In Tanzania, Hemolysis after a Single Dose of Primaquine Coadministered with an Artemisinin Is Not Restricted to Glucose-6-Phosphate Dehydrogenase-Deficient (G6PD A−) Individuals | Antimicrobial Agents and Chemotherapy | 2010 | 93 |
| 22 | Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules | AAPS Journal | 2018 | 86 |
| 23 | Cysteamine restores glutathione redox status in cultured cystinotic proximal tubular epithelial cells | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2011 | 85 |
| 24 | Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4 | British Journal of Pharmacology | 2008 | 81 |
| 25 | Therapeutic implications of renal anionic drug transporters | | 2010 | 81 |
| 26 | Diverse Functional Consequences of Mutations in the Na+/K+-ATPase α2-Subunit Causing Familial Hemiplegic Migraine Type 2 | Journal of Biological Chemistry | 2008 | 79 |
| 27 | Remote ischaemic preconditioning by brief hind limb ischaemia protects against renal ischaemia-reperfusion injury: the role of adenosine | Nephrology Dialysis Transplantation | 2011 | 74 |
| 28 | Rare missense variants inATP1A2 in families with clustering of common forms of migraine | Human Mutation | 2005 | 72 |
| 29 | Reproducibility of blood flow and post-occlusive reactive hyperaemia as measured by venous occlusion plethysmography | Clinical Science | 2005 | 62 |
| 30 | Trends in chloroquine resistance marker, Pfcrt-K76T mutation ten years after chloroquine withdrawal in Tanzania | Malaria Journal | 2013 | 62 |
| 31 | Involvement of VDAC, Bax and Ceramides in the Efflux of AIF from Mitochondria during Curcumin-Induced Apoptosis | PLoS ONE | 2009 | 62 |
| 32 | ABC transporter expression profiling after ischemic reperfusion injury in mouse kidney | Kidney International | 2006 | 61 |
| 33 | Interaction of immunosuppressive drugs with human organic anion transporter (OAT) 1 and OAT3, and multidrug resistance-associated protein (MRP) 2 and MRP4 | Translational Research | 2013 | 61 |
| 34 | Targeting Outpatient Drug Safety | Drug Safety | 2012 | 60 |
| 35 | Epithelial-to-mesenchymal transition in fibrosis: Collagen type I expression is highly upregulated after EMT, but does not contribute to collagen deposition | Experimental Cell Research | 2013 | 57 |
| 36 | Optimized Metabolomic Approach to Identify Uremic Solutes in Plasma of Stage 3–4 Chronic Kidney Disease Patients | PLoS ONE | 2013 | 55 |
| 37 | Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations | CPT: Pharmacometrics and Systems Pharmacology | 2018 | 51 |
| 38 | AMAP, the alleged non-toxic isomer of acetaminophen, is toxic in rat and human liver | Archives of Toxicology | 2013 | 46 |
| 39 | Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP) | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2013 | 46 |
| 40 | Mesenchymal stem cell-conditioned medium accelerates regeneration of human renal proximal tubule epithelial cells after gentamicin toxicity | Experimental and Toxicologic Pathology | 2013 | 46 |
| 41 | Functional Role of Arginine 375 in Transmembrane Helix 6 of Multidrug Resistance Protein 4 (MRP4/ABCC4) | Molecular Pharmacology | 2008 | 44 |
| 42 | Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity | Malaria Journal | 2014 | 43 |
| 43 | Interaction of fluvastatin with the liver-specific Na+-dependent taurocholate cotransporting polypeptide (NTCP) | European Journal of Pharmaceutical Sciences | 2011 | 40 |
| 44 | St. John’s Wort Constituents Modulate P-glycoprotein Transport Activity at the Blood-Brain Barrier | Pharmaceutical Research | 2010 | 39 |
| 45 | Rosuvastatin Increases Extracellular Adenosine Formation in Humans In Vivo | Arteriosclerosis, Thrombosis, and Vascular Biology | 2009 | 37 |
| 46 | Hepcidin suppression and defective iron recycling account for dysregulation of iron homeostasis in heme oxygenase‐1 deficiency | Journal of Cellular and Molecular Medicine | 2009 | 37 |
| 47 | Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2C19 and CYP2D6 and SSRIs | European Journal of Human Genetics | 2022 | 37 |
| 48 | Diannexin Protects against Renal Ischemia Reperfusion Injury and Targets Phosphatidylserines in Ischemic Tissue | PLoS ONE | 2011 | 35 |
| 49 | Subunit-specific Incorporation Efficiency and Kinetics in Mitochondrial Complex I Homeostasis | Journal of Biological Chemistry | 2012 | 34 |
| 50 | Nitric oxide down-regulates the expression of organic cation transporters (OCT) 1 and 2 in rat kidney during endotoxemia | European Journal of Pharmacology | 2008 | 33 |
