# | Title | Journal | Year | Citations |
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1 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
2 | EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update | Annals of the Rheumatic Diseases | 2014 | 1,688 |
3 | Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci | Nature Genetics | 2010 | 1,132 |
4 | Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study | Annals of the Rheumatic Diseases | 2014 | 633 |
5 | The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity | Cell Metabolism | 2010 | 558 |
6 | Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis | Journal of Clinical Investigation | 2008 | 450 |
7 | A simple sample size formula for analysis of covariance in randomized clinical trials | Journal of Clinical Epidemiology | 2007 | 402 |
8 | The Disease Activity Score and the EULAR Response Criteria | Rheumatic Disease Clinics of North America | 2009 | 380 |
9 | The Disease Activity Score and the EULAR response criteria | Clinical and Experimental Rheumatology | 2005 | 342 |
10 | Preliminary criteria for the very early diagnosis of systemic sclerosis: results of a Delphi Consensus Study from EULAR Scleroderma Trials and Research Group | Annals of the Rheumatic Diseases | 2011 | 330 |
11 | Formation of antibodies against infliximab and adalimumab strongly correlates with functional drug levels and clinical responses in rheumatoid arthritis | Annals of the Rheumatic Diseases | 2009 | 329 |
12 | Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci | PLoS Genetics | 2011 | 307 |
13 | The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans | Cell Host and Microbe | 2009 | 294 |
14 | Antiinflammatory and chondroprotective effects of intraarticular injection of adipose‐derived stem cells in experimental osteoarthritis | Arthritis and Rheumatism | 2012 | 286 |
15 | Use of oral prednisolone or naproxen for the treatment of gout arthritis: a double-blind, randomised equivalence trial | Lancet, The | 2008 | 254 |
16 | Dermatological conditions during TNF-alpha-blocking therapy in patients with rheumatoid arthritis: a prospective study | Arthritis Research | 2005 | 232 |
17 | Performance of four current risk algorithms in predicting cardiovascular events in patients with early rheumatoid arthritis | Annals of the Rheumatic Diseases | 2015 | 222 |
18 | Highest clinical effectiveness of rituximab in autoantibody-positive patients with rheumatoid arthritis and in those for whom no more than one previous TNF antagonist has failed: pooled data from 10 European registries | Annals of the Rheumatic Diseases | 2011 | 188 |
19 | Human osteoarthritic synovium impacts chondrogenic differentiation of mesenchymal stem cells via macrophage polarisation state | Osteoarthritis and Cartilage | 2014 | 188 |
20 | Immunochip Analysis Identifies Multiple Susceptibility Loci for Systemic Sclerosis | American Journal of Human Genetics | 2014 | 182 |
21 | Current evidence for the management of rheumatoid arthritis with synthetic disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of rheumatoid arthritis | Annals of the Rheumatic Diseases | 2010 | 179 |
22 | The efficacy of anti-TNF in rheumatoid arthritis, a comparison between randomised controlled trials and clinical practice | Annals of the Rheumatic Diseases | 2007 | 174 |
23 | Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll‐like receptor 4 | Arthritis and Rheumatism | 2012 | 168 |
24 | Preliminary analysis of the Very Early Diagnosis of Systemic Sclerosis (VEDOSS) EUSTAR multicentre study: evidence for puffy fingers as a pivotal sign for suspicion of systemic sclerosis | Annals of the Rheumatic Diseases | 2014 | 168 |
25 | Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis | Annals of the Rheumatic Diseases | 2008 | 161 |
26 | Performance of response criteria for assessing peripheral arthritis in patients with psoriatic arthritis: analysis of data from randomised controlled trials of two tumour necrosis factor inhibitors | Annals of the Rheumatic Diseases | 2006 | 151 |
27 | Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity | Nature Communications | 2014 | 150 |
28 | Toll-like receptors and chronic inflammation in rheumatic diseases: new developments | Nature Reviews Rheumatology | 2016 | 150 |
29 | Long-term follow-up results after autologous haematopoietic stem cell transplantation for severe systemic sclerosis | Annals of the Rheumatic Diseases | 2008 | 149 |
30 | Smad Signaling Determines Chondrogenic Differentiation of Bone-Marrow-Derived Mesenchymal Stem Cells: Inhibition of Smad1/5/8P Prevents Terminal Differentiation and Calcification | Tissue Engineering - Part A | 2011 | 149 |
31 | Cognitive-behavioural therapies and exercise programmes for patients with fibromyalgia: state of the art and future directions | Annals of the Rheumatic Diseases | 2007 | 144 |
32 | A tight control treatment strategy aiming for remission in early rheumatoid arthritis is more effective than usual care treatment in daily clinical practice: a study of two cohorts in the Dutch Rheumatoid Arthritis Monitoring registry | Annals of the Rheumatic Diseases | 2012 | 141 |
33 | Modulation of lipoprotein plasma concentrations during long-term anti-TNF therapy in patients with active rheumatoid arthritis | Annals of the Rheumatic Diseases | 2007 | 136 |
34 | Chronic skin inflammation leads to bone loss by IL-17–mediated inhibition of Wnt signaling in osteoblasts | Science Translational Medicine | 2016 | 133 |
35 | Common and different genetic background for rheumatoid arthritis and coeliac disease | Human Molecular Genetics | 2009 | 128 |
36 | Efficacy and safety of combination etanercept and methotrexate versus etanercept alone in patients with rheumatoid arthritis with an inadequate response to methotrexate: the ADORE study | Annals of the Rheumatic Diseases | 2006 | 125 |
37 | Difference in the risk of serious infections in patients with rheumatoid arthritis treated with adalimumab, infliximab and etanercept: results from the Dutch Rheumatoid Arthritis Monitoring (DREAM) registry | Annals of the Rheumatic Diseases | 2013 | 124 |
38 | Excess mortality emerges after 10 years in an inception cohort of early rheumatoid arthritis | Arthritis Care and Research | 2010 | 122 |
39 | Poly(I:C) Drives Type I IFN- and TGFβ-Mediated Inflammation and Dermal Fibrosis Simulating Altered Gene Expression in Systemic Sclerosis | Journal of Investigative Dermatology | 2010 | 121 |
40 | Meta-analysis of tight control strategies in rheumatoid arthritis: protocolized treatment has additional value with respect to the clinical outcome | Rheumatology | 2010 | 121 |
41 | The effect of disease duration and disease activity on the risk of cardiovascular disease in rheumatoid arthritis patients | Annals of the Rheumatic Diseases | 2015 | 121 |
42 | Tumor necrosis factor–interleukin‐17 interplay induces S100A8, interleukin‐1β, and matrix metalloproteinases, and drives irreversible cartilage destruction in murine arthritis: Rationale for combination treatment during arthritis | Arthritis and Rheumatism | 2011 | 119 |
43 | Linkage of Periodontitis and Rheumatoid Arthritis: Current Evidence and Potential Biological Interactions | International Journal of Molecular Sciences | 2019 | 115 |
44 | Persistent severe fatigue in patients with rheumatoid arthritis | Journal of Clinical Nursing | 2007 | 113 |
45 | Is the disease course of rheumatoid arthritis becoming milder?: Time trends since 1985 in an inception cohort of early rheumatoid arthritis | Arthritis and Rheumatism | 2005 | 112 |
46 | Anti-inflammatory therapy with tumour necrosis factor alpha inhibitors improves high-density lipoprotein cholesterol antioxidative capacity in rheumatoid arthritis patients | Annals of the Rheumatic Diseases | 2009 | 112 |
47 | Assessing the Quality of Clinical Teachers | Journal of General Internal Medicine | 2010 | 111 |
48 | Selective Activation of Adenosine A 2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis | Science Translational Medicine | 2012 | 111 |
49 | Inflammation-dependent secretion and splicing of IL-32γ in rheumatoid arthritis | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 108 |
50 | Construct and criterion validity of several proposed DAS28-based rheumatoid arthritis flare criteria: an OMERACT cohort validation study | Annals of the Rheumatic Diseases | 2013 | 106 |