# | Title | Journal | Year | Citations |
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1 | STAT1 drives M1 microglia activation and neuroinflammation under hypoxia | Archives of Biochemistry and Biophysics | 2019 | 98 |
2 | Metastatic Breast Cancer Cells Enter Into Dormant State and Express Cancer Stem Cells Phenotype Under Chronic Hypoxia | Journal of Cellular Biochemistry | 2017 | 91 |
3 | The chaperone role of the pyridoxal 5′-phosphate and its implications for rare diseases involving B6-dependent enzymes | Clinical Biochemistry | 2014 | 80 |
4 | Redox Regulation of STAT1 and STAT3 Signaling | International Journal of Molecular Sciences | 2020 | 76 |
5 | Tumor Dormancy and Interplay with Hypoxic Tumor Microenvironment | International Journal of Molecular Sciences | 2019 | 74 |
6 | Molecular basis of primary hyperoxaluria: clues to innovative treatments | Urolithiasis | 2019 | 55 |
7 | Structural effects of Mg2+ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction | Biochimica Et Biophysica Acta - Molecular Cell Research | 2015 | 54 |
8 | Pyridoxamine and pyridoxal are more effective than pyridoxine in rescuing folding-defective variants of human alanine:glyoxylate aminotransferase causing primary hyperoxaluria type I | Human Molecular Genetics | 2015 | 50 |
9 | Allosteric communication pathways routed by Ca2+/Mg2+ exchange in GCAP1 selectively switch target regulation modes | Scientific Reports | 2016 | 43 |
10 | Delivery success rate of engineered nanoparticles in the presence of the protein corona: a systems-level screening | Nanomedicine: Nanotechnology, Biology, and Medicine | 2012 | 38 |
11 | Liver peroxisomal alanine:glyoxylate aminotransferase and the effects of mutations associated with Primary Hyperoxaluria Type I: An overview | Biochimica Et Biophysica Acta - Proteins and Proteomics | 2015 | 38 |
12 | Divalent cations modulate membrane binding and pore formation of a potent antibiotic peptide analog of alamethicin | Cell Calcium | 2013 | 36 |
13 | Two retinal dystrophy-associated missense mutations inGUCA1Awith distinct molecular properties result in a similar aberrant regulation of the retinal guanylate cyclase | Human Molecular Genetics | 2015 | 36 |
14 | Biochemical analyses are instrumental in identifying the impact of mutations on holo and/or apo-forms and on the region(s) of alanine:glyoxylate aminotransferase variants associated with Primary Hyperoxaluria Type I | Molecular Genetics and Metabolism | 2012 | 34 |
15 | Nanodevice-induced conformational and functional changes in a prototypical calcium sensor protein | Nanoscale | 2014 | 34 |
16 | Dysfunction of cGMP signalling in photoreceptors by a macular dystrophy-related mutation in the calcium sensor GCAP1 | Human Molecular Genetics | 2017 | 34 |
17 | Gly161 mutations associated with Primary Hyperoxaluria Type I induce the cytosolic aggregation and the intracellular degradation of the apo-form of alanine:glyoxylate aminotransferase | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2013 | 33 |
18 | Structural plasticity of calmodulin on the surface of CaF2nanoparticles preserves its biological function | Nanoscale | 2014 | 33 |
19 | A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger homeostasis in photoreceptors | Human Molecular Genetics | 2018 | 32 |
20 | The N-terminal extension is essential for the formation of the active dimeric structure of liver peroxisomal alanine:glyoxylate aminotransferase | International Journal of Biochemistry and Cell Biology | 2012 | 29 |
21 | S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia | Free Radical Biology and Medicine | 2018 | 29 |
22 | Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses | Human Molecular Genetics | 2019 | 29 |
23 | A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2 | Scientific Reports | 2016 | 27 |
24 | Molecular insights into primary hyperoxaluria Type I pathogenesis | Frontiers in Bioscience - Landmark | 2012 | 26 |
25 | Impact of cone dystrophy-related mutations in GCAP1 on a kinetic model of phototransduction | Cellular and Molecular Life Sciences | 2014 | 26 |
26 | Targeting Cystalysin, a Virulence Factor of Treponema denticola‐Supported Periodontitis | ChemMedChem | 2014 | 26 |
27 | Preferential Binding of Mg2+ Over Ca2+ to CIB2 Triggers an Allosteric Switch Impaired in Usher Syndrome Type 1J | Frontiers in Molecular Neuroscience | 2018 | 26 |
28 | A physiological role for the supramolecular organization of rhodopsin and transducin in rod photoreceptors | FEBS Letters | 2013 | 25 |
29 | Crystal structure of the S187F variant of human liver alanine: Aminotransferase associated with primary hyperoxaluria type I and its functional implications | Proteins: Structure, Function and Bioinformatics | 2013 | 24 |
30 | Mutations in PLS1 , encoding fimbrin, cause autosomal dominant nonsyndromic hearing loss | Human Mutation | 2019 | 23 |
31 | Biochemical and Computational Approaches to Improve the Clinical Treatment of Dopa Decarboxylase-Related Diseases: An Overview | The Open Biochemistry Journal | 2012 | 23 |
32 | Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects | Biochimica Et Biophysica Acta - Proteins and Proteomics | 2021 | 22 |
33 | Rapid Profiling of Disease Alleles Using a Tunable Reporter of Protein Misfolding | Genetics | 2012 | 20 |
34 | Use of polymer conjugates for the intraperoxisomal delivery of engineered human alanine:glyoxylate aminotransferase as a protein therapy for primary hyperoxaluria type I | Nanomedicine: Nanotechnology, Biology, and Medicine | 2017 | 20 |
35 | The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I | ACS Chemical Biology | 2015 | 19 |
36 | New variants of AADC deficiency expand the knowledge of enzymatic phenotypes | Archives of Biochemistry and Biophysics | 2020 | 19 |
37 | Correlation between the molecular effects of mutations at the dimer interface of alanine–glyoxylate aminotransferase leading to primary hyperoxaluria type I and the cellular response to vitamin B6 | Journal of Inherited Metabolic Disease | 2018 | 18 |
38 | Evolutionary-Conserved Allosteric Properties of Three Neuronal Calcium Sensor Proteins | Frontiers in Molecular Neuroscience | 2019 | 18 |
39 | Aromatic Amino Acid Decarboxylase Deficiency: The Added Value of Biochemistry | International Journal of Molecular Sciences | 2021 | 18 |
40 | Allele-specific Characterization of Alanine: Glyoxylate Aminotransferase Variants Associated with Primary Hyperoxaluria | PLoS ONE | 2014 | 17 |
41 | Fingerprints of Calcium-Binding Protein Conformational Dynamics Monitored by Surface Plasmon Resonance | ACS Chemical Biology | 2016 | 17 |
42 | Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A | Scientific Reports | 2019 | 17 |
43 | Electrostatic interactions drive native‐like aggregation of human alanine:glyoxylate aminostransferase | FEBS Journal | 2017 | 15 |
44 | Gut microbiota modulates seizure susceptibility | Epilepsia | 2021 | 15 |
45 | Astrocytes Regulate the Expression of Insulin-Like Growth Factor 1 Receptor (IGF1-R) in Primary Cortical Neurons During In Vitro Senescence | Journal of Molecular Neuroscience | 2010 | 14 |
46 | Polymorphism −2604G>A variants in TLR4 promoter are associated with different gene expression level in peripheral blood of atherosclerotic patients | Journal of Human Genetics | 2013 | 14 |
47 | Natural Sesquiterpene Lactones Enhance Chemosensitivity of Tumor Cells through Redox Regulation of STAT3 Signaling | Oxidative Medicine and Cellular Longevity | 2019 | 14 |
48 | A medieval case of digitalis poisoning: the sudden death of Cangrande della Scala, lord of verona (1291–1329) | Journal of Archaeological Science | 2015 | 13 |
49 | CaF2nanoparticles as surface carriers of GCAP1, a calcium sensor protein involved in retinal dystrophies | Nanoscale | 2017 | 13 |
50 | Folding Defects Leading to Primary Hyperoxaluria | Handbook of Experimental Pharmacology | 2017 | 13 |