| # | Title | Journal | Year | Citations |
|---|
| 1 | Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy | Lancet, The | 1999 | 843 |
| 2 | Future challenges for clinical care of an ageing population infected with HIV: a modelling study | Lancet Infectious Diseases, The | 2015 | 634 |
| 3 | Mean wall thickness of trabecular bone packets in the human iliac crest: Changes with age | Calcified Tissue Research | 1978 | 384 |
| 4 | Effectiveness of discontinuing antibiotic treatment after three days versus eight days in mild to moderate-severe community acquired pneumonia: randomised, double blind study | BMJ: British Medical Journal | 2006 | 259 |
| 5 | Quality and Quantity of Sleep and Factors Associated With Sleep Disturbance in Hospitalized Patients | JAMA Internal Medicine | 2018 | 169 |
| 6 | White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer | Nature Communications | 2020 | 158 |
| 7 | Maintenance therapy after quadruple induction therapy in HIV-1 infected individuals: Amsterdam Duration of Antiretroviral Medication (ADAM) study | Lancet, The | 1998 | 148 |
| 8 | Mortality and progression to AIDS after starting highly active antiretroviral therapy | Aids | 2003 | 147 |
| 9 | Alarming incidence of hepatitis C virus re-infection after treatment of sexually acquired acute hepatitis C virus infection in HIV-infected MSM | Aids | 2011 | 141 |
| 10 | Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and cardiovascular disease | Diabetes Care | 1999 | 133 |
| 11 | Therapeutic drug monitoring of nelfinavir and indinavir in treatment-naive HIV-1-infected individuals | Aids | 2003 | 130 |
| 12 | Antibiotic-Induced Endotoxin Release in Patients with Gram-Negative Urosepsis: A Double-Blind Study Comparing Imipenem and Ceftazidime | Journal of Infectious Diseases | 1995 | 123 |
| 13 | Elevated procoagulant microparticles expressing endothelial and platelet markers in essential thrombocythemia | Haematologica | 2009 | 121 |
| 14 | The effect of plasma drug concentrations on HIV-1 clearance rate during quadruple drug therapy | Aids | 1998 | 113 |
| 15 | First line zidovudine/lamivudine/lopinavir/ritonavir leads to greater bone loss compared to nevirapine/lopinavir/ritonavir | Aids | 2009 | 99 |
| 16 | Herpes zoster, immunological deterioration and disease progression in HIV-1 infection | Aids | 1995 | 95 |
| 17 | Imatinib in patients with severe COVID-19: a randomised, double-blind, placebo-controlled, clinical trial | Lancet Respiratory Medicine,the | 2021 | 83 |
| 18 | Perturbation of hyaluronan metabolism predisposes patients with type 1 diabetes mellitus to atherosclerosis | Diabetologia | 2007 | 80 |
| 19 | Rapid Progression of Albumin Excretion Is an Independent Predictor of Cardiovascular Mortality in Patients With Type 2 Diabetes and Microalbuminuria | Diabetes Care | 2001 | 79 |
| 20 | Risk Factors for Sexual Transmission of Hepatitis C Virus Among Human Immunodeficiency Virus-Infected Men Who Have Sex With Men: A Case-Control Study | Open Forum Infectious Diseases | 2015 | 79 |
| 21 | No Treatment versus 24 or 60 Weeks of Antiretroviral Treatment during Primary HIV Infection: The Randomized Primo-SHM Trial | PLoS Medicine | 2012 | 77 |
| 22 | Continuous glucose monitoring during diabetic pregnancy (GlucoMOMS): A multicentre randomized controlled trial | Diabetes, Obesity and Metabolism | 2018 | 77 |
| 23 | Can reduction in hypertriglyceridaemia slow progression of microalbuminuria in patients with non-insulin-dependent diabetes mellitus? | European Journal of Clinical Investigation | 1997 | 76 |
| 24 | Change to abacavir-lamivudine-tenofovir combination treatment in patients with HIV-1 who had complete virological suppression | Lancet, The | 2003 | 74 |
| 25 | Mitochondrial dysfunction in AIDS and its treatment | Mitochondrion | 2004 | 70 |
| 26 | Adalimumab for Crohn's disease: Long-term sustained benefit in a population-based cohort of 438 patients | Journal of Crohn's and Colitis | 2014 | 69 |
| 27 | Comprehensive Geriatric Assessment and Transitional Care in Acutely Hospitalized Patients | JAMA Internal Medicine | 2016 | 69 |
| 28 | Determinants of Progression of Microalbuminuria in Patients With NIDDM: A prospective study | Diabetes Care | 1997 | 66 |
| 29 | Factors associated with presenting late or with advanced HIV disease in the Netherlands, 1996–2014: results from a national observational cohort | BMJ Open | 2016 | 66 |
| 30 | Health-related quality of life of people with HIV | Aids | 2018 | 59 |
| 31 | Treatment of nucleoside reverse transcriptase inhibitor-induced lactic acidosis | Aids | 2000 | 55 |
| 32 | Malacoplakia. Two case reports and a comparison of treatment modalities based on a literature review | Archives of Internal Medicine | 1996 | 54 |
| 33 | Toxicity and drug exposure in a quadruple drug regimen in HIV–1 infected patients participating in the ADAM study | Aids | 2000 | 52 |
| 34 | Colonial History and Contemporary Transmission Shape the Genetic Diversity of Hepatitis C Virus Genotype 2 in Amsterdam | Journal of Virology | 2012 | 48 |
| 35 | More co‐morbid depression in patients with Type 2 diabetes with multiple complications. An observational study at a specialized outpatient clinic | Diabetic Medicine | 2011 | 47 |
| 36 | Clinical, immunological and virological response to different antiretroviral regimens in a cohort of HIV-2-infected patients | Aids | 2003 | 46 |
| 37 | Lesson of the Week: Hypovitaminosis D in immigrant women: slow to be diagnosed | BMJ: British Medical Journal | 1996 | 46 |
| 38 | Increased carotid intima-media thickness in HIV patients treated with protease inhibitors as compared to non-nucleoside reverse transcriptase inhibitors | Atherosclerosis | 2009 | 44 |
| 39 | Interferon-α as maintenance therapy in patients with multiple myeloma | Annals of Oncology | 2005 | 43 |
| 40 | Chronic renal failure is accompanied by endothelial activation and a large increase in microparticle numbers with reduced procoagulant capacity | Nephrology Dialysis Transplantation | 2012 | 43 |
| 41 | Seasonal variations in the occurrence of Vibriovulnificusalong the Dutch coast | Epidemiology and Infection | 1994 | 42 |
| 42 | Complications of varicella zoster virus reactivation in HIV-infected homosexual men | Aids | 1996 | 42 |
| 43 | Generalized Mycobacterium genavense Infection in HIV-infected Patients: Detection of the Mycobacterium in Hospital Tap Water | Scandinavian Journal of Infectious Diseases | 1999 | 41 |
| 44 | The Power of Flash Mob Research | Chest | 2017 | 40 |
| 45 | Accumulation of advanced glycation end products is associated with macrovascular events and glycaemic control with microvascular complications in Type 2 diabetes mellitus | Diabetic Medicine | 2018 | 40 |
| 46 | The Facilitating Role of Chemotherapy in the Palliative Phase of Cancer: Qualitative Interviews with Advanced Cancer Patients | PLoS ONE | 2013 | 40 |
| 47 | Future Acceptance of an Artificial Pancreas in Adults with Type 1 Diabetes | Diabetes Technology and Therapeutics | 2011 | 39 |
| 48 | Effect of No Prehydration vs Sodium Bicarbonate Prehydration Prior to Contrast-Enhanced Computed Tomography in the Prevention of Postcontrast Acute Kidney Injury in Adults With Chronic Kidney Disease | JAMA Internal Medicine | 2020 | 39 |
| 49 | Immune dysfunction in HIV-seronegative, Cryptococcus gattii meningitis | Journal of Infection | 2007 | 37 |
| 50 | Interaction of Ginkgo biloba with efavirenz | Aids | 2009 | 35 |
