| Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome: the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) Trial | Circulation | 2004 | 667 |
| Bidirectional relation between inflammation and coagulation | Circulation | 2004 | 649 |
| Spotty calcification typifies the culprit plaque in patients with acute myocardial infarction: an intravascular ultrasound study | Circulation | 2004 | 523 |
| Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation | Journal of Thrombosis and Haemostasis | 2004 | 371 |
| Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation | Nature Genetics | 2004 | 321 |
| Daily nighttime melatonin reduces blood pressure in male patients with essential hypertension | Hypertension | 2004 | 321 |
| Prostanoids and prostanoid receptors in signal transduction | International Journal of Biochemistry and Cell Biology | 2004 | 299 |
| IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection | Journal of Immunology | 2004 | 275 |
| Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection | Journal of Immunology | 2004 | 254 |
| Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense | Journal of Immunology | 2004 | 229 |
| Extensive screening for occult malignant disease in idiopathic venous thromboembolism: a prospective randomized clinical trial | Journal of Thrombosis and Haemostasis | 2004 | 216 |
| Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon | Gastroenterology | 2004 | 216 |
| Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice | Infection and Immunity | 2004 | 203 |
| Enzyme therapy for Fabry disease: neutralizing antibodies toward agalsidase alpha and beta | Kidney International | 2004 | 187 |
| Continuous subcutaneous insulin infusion versus multiple daily injections: the impact of baseline A1c | Diabetes Care | 2004 | 186 |
| Pressure relief and load redistribution by custom-made insoles in diabetic patients with neuropathy and foot deformity | Clinical Biomechanics | 2004 | 179 |
| Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1 | PLoS Medicine | 2004 | 176 |
| Lactobacillus rhamnosus induces peripheral hyporesponsiveness in stimulated CD4+ T cells via modulation of dendritic cell function | American Journal of Clinical Nutrition | 2004 | 160 |
| Metformin and lactic acidosis: cause or coincidence? A review of case reports | Journal of Internal Medicine | 2004 | 142 |
| Systematic review: antihypertensive drug therapy in black patients | Annals of Internal Medicine | 2004 | 138 |
| Macrolide activities beyond their antimicrobial effects: macrolides in diffuse panbronchiolitis and cystic fibrosis | Journal of Antimicrobial Chemotherapy | 2004 | 133 |
| Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia | Journal of Immunology | 2004 | 127 |
| Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study | Arthritis Research | 2004 | 108 |
| A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease | Journal of the American College of Cardiology | 2004 | 103 |
| New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology | Annals of Medicine | 2004 | 102 |
