| # | Title | Journal | Year | Citations |
|---|
| 1 | Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome | Gastroenterology | 2012 | 2,287 |
| 2 | Glucose variability is associated with intensive care unit mortality* | Critical Care Medicine | 2010 | 916 |
| 3 | Evaluation of short-term consequences of hypoglycemia in an intensive care unit* | Critical Care Medicine | 2006 | 767 |
| 4 | Fifteen years experience with finger arterial pressure monitoring: assessment of the technology | Cardiovascular Research | 1998 | 690 |
| 5 | Loss of Endothelial Glycocalyx During Acute Hyperglycemia Coincides With Endothelial Dysfunction and Coagulation Activation In Vivo | Diabetes | 2006 | 469 |
| 6 | Exenatide Reduces Infarct Size and Improves Cardiac Function in a Porcine Model of Ischemia and Reperfusion Injury | Journal of the American College of Cardiology | 2009 | 422 |
| 7 | Ventilation with lower tidal volumes as compared with conventional tidal volumes for patients without acute lung injury: a preventive randomized controlled trial | Critical Care | 2010 | 416 |
| 8 | Primary immune responses to human CMV: a critical role for IFN-γ–producing CD4+ T cells in protection against CMV disease | Blood | 2003 | 391 |
| 9 | Glucose Variability; Does It Matter? | Endocrine Reviews | 2010 | 364 |
| 10 | Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes | Diabetes | 2006 | 361 |
| 11 | Initial orthostatic hypotension: review of a forgotten condition | Clinical Science | 2007 | 319 |
| 12 | Predisposing factors for hypoglycemia in the intensive care unit* | Critical Care Medicine | 2006 | 316 |
| 13 | Emergence of a CD4+CD28− Granzyme B+, Cytomegalovirus-Specific T Cell Subset after Recovery of Primary Cytomegalovirus Infection | Journal of Immunology | 2004 | 314 |
| 14 | Early Neurodegeneration in the Retina of Type 2 Diabetic Patients | Journal of Immunology | 2012 | 273 |
| 15 | Continuous stroke volume monitoring by modelling flow from non-invasive measurement of arterial pressure in humans under orthostatic stress | Clinical Science | 1999 | 260 |
| 16 | Effectiveness of discontinuing antibiotic treatment after three days versus eight days in mild to moderate-severe community acquired pneumonia: randomised, double blind study | BMJ: British Medical Journal | 2006 | 259 |
| 17 | Prevalence of orthostatic hypotension in Parkinson’s disease: A systematic review and meta-analysis | Parkinsonism and Related Disorders | 2011 | 259 |
| 18 | Effectiveness of Physical Counterpressure Maneuvers in Preventing Vasovagal Syncope | Journal of the American College of Cardiology | 2006 | 256 |
| 19 | Validation of the Charlson Comorbidity Index in Acutely Hospitalized Elderly Adults: A Prospective Cohort Study | Journal of the American Geriatrics Society | 2014 | 254 |
| 20 | Continuous stroke volume monitoring by modelling flow from non-invasive measurement of arterial pressure in humans under orthostatic stress | Clinical Science | 1999 | 252 |
| 21 | Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects | American Journal of Human Genetics | 2018 | 252 |
| 22 | Recommendations for initiation and cessation of enzyme replacement therapy in patients with Fabry disease: the European Fabry Working Group consensus document | Orphanet Journal of Rare Diseases | 2015 | 239 |
| 23 | Pathophysiology and treatment of haemodynamic instability in acute pulmonary embolism: the pivotal role of pulmonary vasoconstriction | Cardiovascular Research | 2000 | 237 |
| 24 | Clinical Pharmacology and Therapeutic Potential of Artemisinin and its Derivatives in the Treatment of Malaria | Drugs | 1996 | 232 |
| 25 | Continuous Subcutaneous Insulin Infusion Versus Multiple Daily Injections: The impact of baseline A1c | Diabetes Care | 2004 | 222 |
| 26 | Cytokines and acute phase response in delirium | Journal of Psychosomatic Research | 2007 | 217 |
| 27 | Evaluating Causality of Gut Microbiota in Obesity and Diabetes in Humans | Endocrine Reviews | 2018 | 207 |
| 28 | Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial | Lancet, The | 2017 | 204 |
| 29 | Differentiation of cytomegalovirus-specific CD8+ T cells in healthy and immunosuppressed virus carriers | Blood | 2001 | 186 |
| 30 | Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans | Journal of Allergy and Clinical Immunology | 2018 | 185 |
| 31 | Lactobacilli vs Antibiotics to Prevent Urinary Tract Infections | Archives of Internal Medicine | 2012 | 177 |
| 32 | Percentiles for skeletal muscle index, area and radiation attenuation based on computed tomography imaging in a healthy Caucasian population | European Journal of Clinical Nutrition | 2018 | 177 |
| 33 | Metformin and lactic acidosis: cause or coincidence? A review of case reports | Journal of Internal Medicine | 2004 | 172 |
| 34 | Tissue factor and coronary artery disease | Cardiovascular Research | 2002 | 171 |
| 35 | Glucose fluctuations and activation of oxidative stress in patients with type 1 diabetes | Diabetologia | 2007 | 169 |
| 36 | Quality and Quantity of Sleep and Factors Associated With Sleep Disturbance in Hospitalized Patients | JAMA Internal Medicine | 2018 | 169 |
| 37 | Systematic Review: Antihypertensive Drug Therapy in Black Patients | Annals of Internal Medicine | 2004 | 163 |
| 38 | Nonantibiotic Prophylaxis for Recurrent Urinary Tract Infections: A Systematic Review and Meta-Analysis of Randomized Controlled Trials | Journal of Urology | 2013 | 159 |
| 39 | ESC Council on hypertension position document on the management of hypertensive emergencies | European Heart Journal - Cardiovascular Pharmacotherapy | 2019 | 155 |
| 40 | Early switch from intravenous to oral antibiotics: guidelines and implementation in a large teaching hospital | Journal of Antimicrobial Chemotherapy | 1999 | 154 |
| 41 | Human Cytomegalovirus Induces Systemic Immune Activation Characterized by a Type 1 Cytokine Signature | Journal of Infectious Diseases | 2010 | 148 |
| 42 | Muscle Tensing During Standing | Stroke | 2001 | 145 |
| 43 | CD103 Is a Marker for Alloantigen-Induced Regulatory CD8+ T Cells | Journal of Immunology | 2006 | 145 |
| 44 | A 24-Week, Randomized, Treat-to-Target Trial Comparing Initiation of Insulin Glargine Once-Daily With Insulin Detemir Twice-Daily in Patients With Type 2 Diabetes Inadequately Controlled on Oral Glucose-Lowering Drugs | Diabetes Care | 2010 | 145 |
| 45 | Assessment of splenic function | European Journal of Clinical Microbiology and Infectious Diseases | 2010 | 142 |
| 46 | Alefacept treatment in psoriatic arthritis: Reduction of the effector T cell population in peripheral blood and synovial tissue is associated with improvement of clinical signs of arthritis | Arthritis and Rheumatism | 2002 | 140 |
| 47 | Short-term and long-term mortality in very elderly patients admitted to an intensive care unit | Intensive Care Medicine | 2006 | 140 |
| 48 | Insulin Therapy for Type 2 Diabetes | Diabetes Care | 2009 | 140 |
| 49 | Clinical Presentations and Epidemiology of Urinary Tract Infections | Microbiology Spectrum | 2016 | 140 |
| 50 | Proliferation Requirements of Cytomegalovirus-Specific, Effector-Type Human CD8+ T Cells | Journal of Immunology | 2002 | 138 |
