| # | Title | Journal | Year | Citations |
|---|
| 1 | Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution | Cell Cycle | 2010 | 400 |
| 2 | Autophagy in cancer associated fibroblasts promotes tumor cell survival | Cell Cycle | 2010 | 377 |
| 3 | A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation | Journal of Cell Biology | 2008 | 342 |
| 4 | Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease | American Journal of Pathology | 2012 | 321 |
| 5 | CHECKPOINT INHIBITOR IMMUNE THERAPY | Retina | 2018 | 252 |
| 6 | Caveolin-1 and Cancer Metabolism in the Tumor Microenvironment: Markers, Models, and Mechanisms | Annual Review of Pathology: Mechanisms of Disease | 2012 | 249 |
| 7 | Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development | Seminars in Oncology | 2017 | 239 |
| 8 | Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: Implications for breast cancer and DCIS therapy with autophagy inhibitors | Cell Cycle | 2010 | 238 |
| 9 | Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma | Seminars in Oncology | 2014 | 226 |
| 10 | Stromal–epithelial metabolic coupling in cancer: Integrating autophagy and metabolism in the tumor microenvironment | International Journal of Biochemistry and Cell Biology | 2011 | 218 |
| 11 | Interleukin 10 in the tumor microenvironment: a target for anticancer immunotherapy | Immunologic Research | 2011 | 215 |
| 12 | Phase I Evaluation of Intravenous Ascorbic Acid in Combination with Gemcitabine and Erlotinib in Patients with Metastatic Pancreatic Cancer | PLoS ONE | 2012 | 213 |
| 13 | A randomized controlled trial of the impact of targeted and tailored interventions on colorectal cancer screening | Cancer | 2007 | 197 |
| 14 | Caveolae and signalling in cancer | Nature Reviews Cancer | 2015 | 185 |
| 15 | Understanding the "lethal" drivers of tumor-stroma co-evolution | Cancer Biology and Therapy | 2010 | 180 |
| 16 | Meta-analysis in metastatic uveal melanoma to determine progression free and overall survival benchmarks: an international rare cancers initiative (IRCI) ocular melanoma study | Annals of Oncology | 2019 | 171 |
| 17 | Implementation of Germline Testing for Prostate Cancer: Philadelphia Prostate Cancer Consensus Conference 2019 | Journal of Clinical Oncology | 2020 | 170 |
| 18 | CD147 reprograms fatty acid metabolism in hepatocellular carcinoma cells through Akt/mTOR/SREBP1c and P38/PPARα pathways | Journal of Hepatology | 2015 | 166 |
| 19 | Longitudinally collected CTCs and CTC-clusters and clinical outcomes of metastatic breast cancer | Breast Cancer Research and Treatment | 2017 | 156 |
| 20 | Association of K-ras Mutational Status and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Receiving Panitumumab Alone | Clinical Colorectal Cancer | 2008 | 147 |
| 21 | Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells | Cancer Biology and Therapy | 2011 | 145 |
| 22 | Narrative Health Communication and Behavior Change: The Influence of Exemplars in the News on Intention to Quit Smoking | Journal of Communication | 2012 | 144 |
| 23 | Berzosertib plus gemcitabine versus gemcitabine alone in platinum-resistant high-grade serous ovarian cancer: a multicentre, open-label, randomised, phase 2 trial | Lancet Oncology, The | 2020 | 140 |
| 24 | Multiple mismatches at the low expression HLA loci DP, DQ, and DRB3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation | Blood | 2013 | 137 |
| 25 | Adjuvant chemotherapy with or without bevacizumab in patients with resected non-small-cell lung cancer (E1505): an open-label, multicentre, randomised, phase 3 trial | Lancet Oncology, The | 2017 | 136 |
| 26 | Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: Similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling" | Aging | 2010 | 136 |
| 27 | Quality of life with palbociclib plus fulvestrant in previously treated hormone receptor-positive, HER2-negative metastatic breast cancer: patient-reported outcomes from the PALOMA-3 trial | Annals of Oncology | 2016 | 133 |
| 28 | MCU-dependent mitochondrial Ca2+ inhibits NAD+/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells | Oncogene | 2017 | 132 |
| 29 | CD147 promotes reprogramming of glucose metabolism and cell proliferation in HCC cells by inhibiting the p53-dependent signaling pathway | Journal of Hepatology | 2014 | 124 |
| 30 | Prospective assessment of the prognostic value of circulating tumor cells and their clusters in patients with advanced-stage breast cancer | Breast Cancer Research and Treatment | 2015 | 124 |
| 31 | TGF‐β1 targets Smad, p38 MAPK, and PI3K/Akt signaling pathways to induce PFKFB3 gene expression and glycolysis in glioblastoma cells | FEBS Journal | 2017 | 116 |
| 32 | Applying Multiple Data Collection Tools to Quantify Human Papillomavirus Vaccine Communication on Twitter | Journal of Medical Internet Research | 2016 | 115 |
| 33 | Targeting the Bcl-2 Family in B Cell Lymphoma | Frontiers in Oncology | 2018 | 106 |
| 34 | Phase 1 Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma Patients With Brain Metastases | International Journal of Radiation Oncology Biology Physics | 2017 | 103 |
| 35 | Epidermal growth factor receptor and insulinlike growth factor 1 receptor expression predict poor survival in pancreatic ductal adenocarcinoma | Cancer | 2012 | 99 |
| 36 | TP53 mutations detected in circulating tumor cells present in the blood of metastatic triple negative breast cancer patients | Breast Cancer Research | 2014 | 97 |
| 37 | Effects of Cancer Stage and Treatment Differences on Racial Disparities in Survival From Colon Cancer: A United States Population-Based Study | Gastroenterology | 2016 | 92 |
| 38 | Multiregion whole-exome sequencing of matched primary and metastatic tumors revealed genomic heterogeneity and suggested polyclonal seeding in colorectal cancer metastasis | Annals of Oncology | 2017 | 92 |
| 39 | Emergency use of uridine triacetate for the prevention and treatment of life‐threatening 5‐fluorouracil and capecitabine toxicity | Cancer | 2017 | 91 |
| 40 | Effects of Vitamin D Supplementation on Prevention of Type 2 Diabetes in Patients With Prediabetes: A Systematic Review and Meta-analysis | Diabetes Care | 2020 | 91 |
| 41 | Prognostic Significance of Tumor-Associated Macrophage Content in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis | Frontiers in Oncology | 2019 | 87 |
| 42 | Locoregional Management of Hepatic Metastasis From Primary Uveal Melanoma | Seminars in Oncology | 2010 | 84 |
| 43 | Comprehensive genomic profiles of metastatic and relapsed salivary gland carcinomas are associated with tumor type and reveal new routes to targeted therapies | Annals of Oncology | 2017 | 84 |
| 44 | Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped Lentivector | Frontiers in Immunology | 2019 | 84 |
| 45 | Immunoembolization of Malignant Liver Tumors, Including Uveal Melanoma, Using Granulocyte-Macrophage Colony-Stimulating Factor | Journal of Clinical Oncology | 2008 | 83 |
| 46 | Phase I Trial Using Proteasome Inhibitor Bortezomib and Concurrent Temozolomide and Radiotherapy for Central Nervous System Malignancies | International Journal of Radiation Oncology Biology Physics | 2009 | 83 |
| 47 | Fructose 2,6-Bisphosphate in Cancer Cell Metabolism | Frontiers in Oncology | 2018 | 83 |
| 48 | CTC enumeration and characterization: moving toward personalized medicine | Annals of Translational Medicine | 2014 | 83 |
| 49 | Epigenetic regulation of nuclear steroid receptors | Biochemical Pharmacology | 2006 | 80 |
| 50 | Gender differences in attitudes impeding colorectal cancer screening | BMC Public Health | 2013 | 79 |
