| # | Title | Journal | Year | Citations |
|---|
| 1 | Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration | Lancet Neurology, The | 2013 | 3,919 |
| 2 | Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis | Lancet Neurology, The | 2010 | 2,035 |
| 3 | Risk of dementia in diabetes mellitus: a systematic review | Lancet Neurology, The | 2006 | 1,791 |
| 4 | Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials | Lancet Neurology, The | 2007 | 1,580 |
| 5 | Systematic identification of trans eQTLs as putative drivers of known disease associations | Nature Genetics | 2013 | 1,544 |
| 6 | Subarachnoid haemorrhage | Lancet, The | 2007 | 1,453 |
| 7 | 1,026 Experimental treatments in acute stroke | Annals of Neurology | 2006 | 1,238 |
| 8 | Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 | Nature Genetics | 2011 | 1,201 |
| 9 | Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials | Lancet, The | 2010 | 1,168 |
| 10 | Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis | Lancet Neurology, The | 2009 | 1,079 |
| 11 | Can Animal Models of Disease Reliably Inform Human Studies? | PLoS Medicine | 2010 | 1,026 |
| 12 | Incidence of subarachnoid haemorrhage: a systematic review with emphasis on region, age, gender and time trends | Journal of Neurology, Neurosurgery and Psychiatry | 2007 | 934 |
| 13 | Amyotrophic lateral sclerosis | Nature Reviews Disease Primers | 2017 | 885 |
| 14 | Multiple common variants for celiac disease influencing immune gene expression | Nature Genetics | 2010 | 871 |
| 15 | Amyotrophic lateral sclerosis | Lancet, The | 2017 | 867 |
| 16 | Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways | Science | 2015 | 823 |
| 17 | Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial | Lancet Neurology, The | 2009 | 805 |
| 18 | Very Small Cerebellar Infarcts: Integration of Recent Insights into a Functional Topographic Classification | Cerebrovascular Diseases | 2013 | 739 |
| 19 | Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications | Nature Reviews Endocrinology | 2018 | 689 |
| 20 | The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm | Nature Genetics | 2008 | 668 |
| 21 | Cognitive deficits in adult patients with brain tumours | Lancet Neurology, The | 2004 | 641 |
| 22 | Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression | Nature Genetics | 2021 | 590 |
| 23 | Cognition and diabetes: a lifespan perspective | Lancet Neurology, The | 2008 | 557 |
| 24 | Risk of Rupture of Unruptured Intracranial Aneurysms in Relation to Patient and Aneurysm Characteristics | Stroke | 2007 | 543 |
| 25 | Aging effects on DNA methylation modules in human brain and blood tissue | Genome Biology | 2012 | 536 |
| 26 | Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis | Nature | 2012 | 522 |
| 27 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene | Neuron | 2018 | 517 |
| 28 | New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS) | Lancet Neurology, The | 2010 | 509 |
| 29 | Clinical diagnosis and management of amyotrophic lateral sclerosis | Nature Reviews Neurology | 2011 | 503 |
| 30 | Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis | Nature Genetics | 2016 | 494 |
| 31 | Hypertension and cerebral white matter lesions in a prospective cohort study | Brain | 2002 | 463 |
| 32 | Controversies and priorities in amyotrophic lateral sclerosis | Lancet Neurology, The | 2013 | 454 |
| 33 | Vascular dysfunction—The disregarded partner of Alzheimer's disease | Alzheimer's and Dementia | 2019 | 454 |
| 34 | The genetic architecture of the human cerebral cortex | Science | 2020 | 450 |
| 35 | Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons | Nature Medicine | 2018 | 445 |
| 36 | Dementia and cognitive decline in type 2 diabetes and prediabetic stages: towards targeted interventions | Lancet Diabetes and Endocrinology,the | 2014 | 431 |
| 37 | Proportional thresholding in resting-state fMRI functional connectivity networks and consequences for patient-control connectome studies: Issues and recommendations | NeuroImage | 2017 | 402 |
| 38 | Hippocampal insulin resistance and cognitive dysfunction | Nature Reviews Neuroscience | 2015 | 396 |
| 39 | Methodological considerations on tract-based spatial statistics (TBSS) | NeuroImage | 2014 | 395 |
| 40 | Disease variants alter transcription factor levels and methylation of their binding sites | Nature Genetics | 2017 | 390 |
| 41 | Long-term outcomes of patients with aneurysmal subarachnoid haemorrhage | Lancet Neurology, The | 2011 | 384 |
| 42 | Diabetes, hyperglycaemia, and acute ischaemic stroke | Lancet Neurology, The | 2012 | 377 |
| 43 | Identification of context-dependent expression quantitative trait loci in whole blood | Nature Genetics | 2017 | 363 |
| 44 | Epilepsy in low-grade gliomas: The impact on cognitive function and quality of life | Annals of Neurology | 2003 | 358 |
| 45 | Inflammatory Cell Adhesion Molecules in Ischemic Cerebrovascular Disease | Stroke | 2002 | 352 |
| 46 | Calcium antagonists for aneurysmal subarachnoid haemorrhage | The Cochrane Library | 2007 | 344 |
| 47 | Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis | Nature Genetics | 2009 | 344 |
| 48 | Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model | Lancet Neurology, The | 2018 | 342 |
| 49 | Sex differences in the perception of affective facial expressions: Do men really lack emotional sensitivity? | Cognitive Processing | 2005 | 333 |
| 50 | Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA | PLoS Genetics | 2011 | 324 |
