| # | Title | Journal | Year | Citations |
|---|
| 1 | The biology of incretin hormones | Cell Metabolism | 2006 | 1,824 |
| 2 | Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma | Gastroenterology | 2016 | 1,365 |
| 3 | Hypertrophic cardiomyopathy. The importance of the site and the extent of hypertrophy. A review | Progress in Cardiovascular Diseases | 1985 | 751 |
| 4 | Oxford Classification of IgA nephropathy 2016: an update from the IgA Nephropathy Classification Working Group | Kidney International | 2017 | 748 |
| 5 | Glucagon-like peptide-1 receptor is involved in learning and neuroprotection | Nature Medicine | 2003 | 722 |
| 6 | Cardiac morbidity and mortality related to orthotopic liver transplantation | Liver Transplantation | 2004 | 682 |
| 7 | Glucagon-like Peptide-1 Receptor Signaling Modulates β Cell Apoptosis | Journal of Biological Chemistry | 2003 | 524 |
| 8 | Enhancing Incretin Action for the Treatment of Type 2 Diabetes | Diabetes Care | 2003 | 510 |
| 9 | Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis | Postgraduate Medical Journal | 2008 | 504 |
| 10 | Transjugular Intrahepatic Portosystemic Shunt for Refractory Ascites: A Meta-analysis of Individual Patient Data | Gastroenterology | 2007 | 494 |
| 11 | Biological actions and therapeutic potential of the glucagon-like peptides | Gastroenterology | 2002 | 460 |
| 12 | Glucagon-Like Peptides: Regulators of Cell Proliferation, Differentiation, and Apoptosis | Molecular Endocrinology | 2003 | 444 |
| 13 | Entecavir for Treatment of Lamivudine-Refractory, HBeAg-Positive Chronic Hepatitis B | Gastroenterology | 2006 | 391 |
| 14 | Midodrine, octreotide, albumin, and TIPS in selected patients with cirrhosis and type 1 hepatorenal syndrome | Hepatology | 2004 | 369 |
| 15 | Working Party proposal for a revised classification system of renal dysfunction in patients with cirrhosis | Gut | 2011 | 359 |
| 16 | Minireview: The Glucagon-Like Peptides | Endocrinology | 2001 | 356 |
| 17 | Hyponatremia in cirrhosis: Results of a patient population survey | Hepatology | 2006 | 349 |
| 18 | Evaluating the Accuracy of Nutritional Assessment Techniques Applied To Hospitalized Patients: Methodology and Comparisons | Journal of Parenteral and Enteral Nutrition | 1984 | 330 |
| 19 | Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure | Gastroenterology | 2004 | 320 |
| 20 | A Recombinant Human Glucagon-Like Peptide (GLP)-1-Albumin Protein (Albugon) Mimics Peptidergic Activation of GLP-1 Receptor-Dependent Pathways Coupled With Satiety, Gastrointestinal Motility, and Glucose Homeostasis | Diabetes | 2004 | 318 |
| 21 | Enteroendocrine localization of GLP-2 receptor expression in humans and rodents | Gastroenterology | 2000 | 297 |
| 22 | Combination of Tenofovir Disoproxil Fumarate and Peginterferon α-2a Increases Loss of Hepatitis B Surface Antigen in Patients With Chronic Hepatitis B | Gastroenterology | 2016 | 284 |
| 23 | Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors | Diabetes | 2004 | 283 |
| 24 | A vasopressin receptor antagonist (VPA-985) improves serum sodium concentration in patients with hyponatremia: A multicenter, randomized, placebo-controlled trial | Hepatology | 2003 | 269 |
| 25 | New Evidence for Stroke Prevention | JAMA - Journal of the American Medical Association | 2002 | 266 |
| 26 | Renoprotective effects of sodium-glucose cotransporter-2 inhibitors | Kidney International | 2018 | 262 |
| 27 | Glucagon-Like Peptide-1 and the Islet β-Cell: Augmentation of Cell Proliferation and Inhibition of Apoptosis | Endocrinology | 2003 | 258 |
| 28 | Glucagon-Like Peptide-1-Responsive Catecholamine Neurons in the Area Postrema Link Peripheral Glucagon-Like Peptide-1 with Central Autonomic Control Sites | Journal of Neuroscience | 2003 | 248 |
| 29 | Late risk of outcomes for adults with repaired tetralogy of Fallot from an inception cohort spanning four decades☆ | European Journal of Cardio-thoracic Surgery | 2009 | 242 |
| 30 | Empagliflozin as Adjunctive to Insulin Therapy in Type 1 Diabetes: The EASE Trials | Diabetes Care | 2018 | 239 |
| 31 | The actions of SGLT2 inhibitors on metabolism, renal function and blood pressure | Diabetologia | 2018 | 234 |
| 32 | Staging of hepatocellular carcinoma: assessment of the CLIP, Okuda, and Child-Pugh staging systems in a cohort of 257 patients in Toronto | Gut | 2002 | 214 |
| 33 | -Cell Pdx1 Expression Is Essential for the Glucoregulatory, Proliferative, and Cytoprotective Actions of Glucagon-Like Peptide-1 | Diabetes | 2005 | 213 |
| 34 | Development and Characterization of a Glucagon-Like Peptide 1-Albumin Conjugate: The Ability to Activate the Glucagon-Like Peptide 1 Receptor In Vivo | Diabetes | 2003 | 212 |
| 35 | Glucagon gene expression in vertebrate brain. | Journal of Biological Chemistry | 1988 | 212 |
| 36 | Sodium-Glucose Cotransporter 2 Inhibition and Glycemic Control in Type 1 Diabetes: Results of an 8-Week Open-Label Proof-of-Concept Trial | Diabetes Care | 2014 | 211 |
| 37 | The role of antimalarial agents in the treatment of SLE and lupus nephritis | Nature Reviews Nephrology | 2011 | 207 |
| 38 | Acute kidney injury in decompensated cirrhosis | Gut | 2013 | 205 |
| 39 | A Simple Serum Iron Method Using the New Sensitive Chromogen Tripyridyl-s-triazine | Clinical Chemistry | 1964 | 204 |
| 40 | Results of Single-Lung Transplantation for Bilateral Pulmonary Fibrosis | New England Journal of Medicine | 1990 | 200 |
| 41 | Molecularly Targeted Oncology Therapeutics and Prolongation of the QT Interval | Journal of Clinical Oncology | 2007 | 198 |
| 42 | Therapeutic potential of dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes | Expert Opinion on Investigational Drugs | 2003 | 197 |
| 43 | Fluid Shift by Lower Body Positive Pressure Increases Pharyngeal Resistance in Healthy Subjects | American Journal of Respiratory and Critical Care Medicine | 2006 | 197 |
| 44 | Hemodynamic Effects of Simulated Obstructive Apneas in Humans With and Without Heart Failure | Chest | 2001 | 196 |
| 45 | Nonalcoholic fatty liver disease is associated with dysbiosis independent of body mass index and insulin resistance | Scientific Reports | 2018 | 196 |
| 46 | Guidelines for the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria and related disorders by flow cytometry | Cytometry Part B - Clinical Cytometry | 2010 | 195 |
| 47 | Cumulative Patency of Contemporary Fistulas versus Grafts (2000–2010) | Clinical Journal of the American Society of Nephrology: CJASN | 2013 | 193 |
| 48 | Circulating Viral and Thyroid Antibodies in Subacute Thyroiditis1 | Journal of Clinical Endocrinology and Metabolism | 1967 | 192 |
| 49 | Standardized Definitions for Hemodialysis Vascular Access | Seminars in Dialysis | 2011 | 191 |
| 50 | Irritant-Induced Occupational Asthma | Chest | 1989 | 184 |
