| # | Title | Journal | Year | Citations |
|---|
| 1 | Tumor mutational load predicts survival after immunotherapy across multiple cancer types | Nature Genetics | 2019 | 2,702 |
| 2 | Extrapulmonary manifestations of COVID-19 | Nature Medicine | 2020 | 2,300 |
| 3 | Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study | Lancet, The | 2020 | 1,780 |
| 4 | Transcriptional Responses to Polypeptide Ligands: The JAK-STAT Pathway | Annual Review of Biochemistry | 1995 | 1,762 |
| 5 | Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma | Cancer Cell | 2014 | 1,616 |
| 6 | Subendothelial Lipoprotein Retention as the Initiating Process in Atherosclerosis | Circulation | 2007 | 1,123 |
| 7 | Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program | Nature | 2021 | 1,069 |
| 8 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 9 | Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis | BMJ: British Medical Journal | 2019 | 856 |
| 10 | Molecular genetics of prostate cancer: new prospects for old challenges | Genes and Development | 2010 | 811 |
| 11 | Oncogene Addiction | Cancer Research | 2008 | 801 |
| 12 | The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction | Nature | 1993 | 785 |
| 13 | Impact of Major Bleeding on 30-Day Mortality and Clinical Outcomes in Patients With Acute Coronary Syndromes | Journal of the American College of Cardiology | 2007 | 776 |
| 14 | Radiation Dose to Patients From Cardiac Diagnostic Imaging | Circulation | 2007 | 727 |
| 15 | Psychological distress, coping behaviors, and preferences for support among New York healthcare workers during the COVID-19 pandemic | General Hospital Psychiatry | 2020 | 708 |
| 16 | Cysteine depletion induces pancreatic tumor ferroptosis in mice | Science | 2020 | 692 |
| 17 | Proton pump inhibitors alter the composition of the gut microbiota | Gut | 2016 | 682 |
| 18 | Randomized Comparison of Percutaneous Repair and Surgery for Mitral Regurgitation | Journal of the American College of Cardiology | 2015 | 658 |
| 19 | Adherence to Bisphosphonate Therapy and Fracture Rates in Osteoporotic Women: Relationship to Vertebral and Nonvertebral Fractures From 2 US Claims Databases | Mayo Clinic Proceedings | 2006 | 652 |
| 20 | State of the Art Review: Depression, Stress, Anxiety, and Cardiovascular Disease | American Journal of Hypertension | 2015 | 628 |
| 21 | Inflammation and plaque vulnerability | Journal of Internal Medicine | 2015 | 596 |
| 22 | Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series | BMJ, The | 2020 | 588 |
| 23 | Variation in COVID-19 Hospitalizations and Deaths Across New York City Boroughs | JAMA - Journal of the American Medical Association | 2020 | 577 |
| 24 | Transthyretin Amyloid Cardiomyopathy | Journal of the American College of Cardiology | 2019 | 573 |
| 25 | Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma | Nature Medicine | 2019 | 569 |
| 26 | Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer | Cell | 2018 | 540 |
| 27 | COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets | Nature | 2021 | 537 |
| 28 | A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy | Nature | 2017 | 532 |
| 29 | C3 glomerulopathy: consensus report | Kidney International | 2013 | 505 |
| 30 | Efficient generation of lung and airway epithelial cells from human pluripotent stem cells | Nature Biotechnology | 2014 | 497 |
| 31 | Racial/Ethnic Differences in Sleep Disturbances: The Multi-Ethnic Study of Atherosclerosis (MESA) | Sleep | 2015 | 489 |
| 32 | Fluoroscopically Guided Interventional Procedures: A Review of Radiation Effects on Patients’ Skin and Hair | Radiology | 2010 | 483 |
| 33 | Suppression of insulin feedback enhances the efficacy of PI3K inhibitors | Nature | 2018 | 477 |
| 34 | Joint international consensus statement for ending stigma of obesity | Nature Medicine | 2020 | 468 |
| 35 | A three-dimensional model of human lung development and disease from pluripotent stem cells | Nature Cell Biology | 2017 | 467 |
| 36 | Efferocytosis in health and disease | Nature Reviews Immunology | 2020 | 461 |
| 37 | Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients? | American Society of Clinical Oncology Educational Book / ASCO American Society of Clinical Oncology Meeting | 2019 | 459 |
| 38 | Control of Confounding and Reporting of Results in Causal Inference Studies. Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals | Annals of the American Thoracic Society | 2019 | 458 |
| 39 | Agarose-based biomaterials for tissue engineering | Carbohydrate Polymers | 2018 | 454 |
| 40 | The Challenge of HIV-1 Subtype Diversity | New England Journal of Medicine | 2008 | 453 |
| 41 | The clinical diagnosis of osteoporosis: a position statement from the National Bone Health Alliance Working Group | Osteoporosis International | 2014 | 450 |
| 42 | Diagnosis of cobalamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations | American Journal of Hematology | 1990 | 428 |
| 43 | Neoadjuvant atezolizumab and chemotherapy in patients with resectable non-small-cell lung cancer: an open-label, multicentre, single-arm, phase 2 trial | Lancet Oncology, The | 2020 | 419 |
| 44 | Non-Celiac Gluten Sensitivity: The New Frontier of Gluten Related Disorders | Nutrients | 2013 | 418 |
| 45 | The Impact of Frailty Status on Survival After Transcatheter Aortic Valve Replacement in Older Adults With Severe Aortic Stenosis | JACC: Cardiovascular Interventions | 2012 | 411 |
| 46 | A molecular single-cell lung atlas of lethal COVID-19 | Nature | 2021 | 411 |
| 47 | Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum | Nature Immunology | 2021 | 403 |
| 48 | Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake | Nature Medicine | 2006 | 397 |
| 49 | Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-Like Metaplasia | Cancer Cell | 2012 | 395 |
| 50 | Uveal melanoma | Nature Reviews Disease Primers | 2020 | 392 |
