| # | Title | Journal | Year | Citations |
|---|
| 1 | Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration | PLoS Medicine | 2007 | 3,710 |
| 2 | Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal | BMJ, The | 2020 | 2,134 |
| 3 | Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) | Epidemiology | 2007 | 1,717 |
| 4 | Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and elaboration | International Journal of Surgery | 2014 | 1,698 |
| 5 | Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease | Nature Genetics | 2011 | 1,685 |
| 6 | Malignancies, Prothrombotic Mutations, and the Risk of Venous Thrombosis | JAMA - Journal of the American Medical Association | 2005 | 1,639 |
| 7 | Incidence and mortality of venous thrombosis: a population-based study | Journal of Thrombosis and Haemostasis | 2007 | 1,134 |
| 8 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 9 | Epidemiology of cancer-associated venous thrombosis | Blood | 2013 | 914 |
| 10 | Clinical practice guidelines for the care of girls and women with Turner syndrome: proceedings from the 2016 Cincinnati International Turner Syndrome Meeting | European Journal of Endocrinology | 2017 | 771 |
| 11 | Calibration: the Achilles heel of predictive analytics | BMC Medicine | 2019 | 745 |
| 12 | Geographic Distribution of the 20210 G to A Prothrombin Variant | Thrombosis and Haemostasis | 1998 | 675 |
| 13 | Long-term risks for kidney donors | Kidney International | 2014 | 643 |
| 14 | Cardiovascular and Noncardiovascular Mortality Among Patients Starting Dialysis | JAMA - Journal of the American Medical Association | 2009 | 584 |
| 15 | Incidence of venous thrombosis in a large cohort of 66 329 cancer patients: results of a record linkage study | Journal of Thrombosis and Haemostasis | 2006 | 568 |
| 16 | Pregnancy, the postpartum period and prothrombotic defects: risk of venous thrombosis in the MEGA study | Journal of Thrombosis and Haemostasis | 2008 | 560 |
| 17 | A catalog of genetic loci associated with kidney function from analyses of a million individuals | Nature Genetics | 2019 | 549 |
| 18 | Rare and low-frequency coding variants alter human adult height | Nature | 2017 | 544 |
| 19 | On assessing responsiveness of health-related quality of life instruments: guidelines for instrument evaluation | Quality of Life Research | 2003 | 542 |
| 20 | Oral Contraceptives and the Risk of Venous Thrombosis | New England Journal of Medicine | 2001 | 507 |
| 21 | The venous thrombotic risk of oral contraceptives, effects of oestrogen dose and progestogen type: results of the MEGA case-control study | BMJ: British Medical Journal | 2009 | 506 |
| 22 | Thrombophilia, Clinical Factors, and Recurrent Venous Thrombotic Events | JAMA - Journal of the American Medical Association | 2005 | 489 |
| 23 | Performance of the Cockcroft-Gault, MDRD, and New CKD-EPI Formulas in Relation to GFR, Age, and Body Size | Clinical Journal of the American Society of Nephrology: CJASN | 2010 | 461 |
| 24 | Treatment-related risk factors of inhibitor development in previously untreated patients with hemophilia A: the CANAL cohort study | Blood | 2007 | 449 |
| 25 | Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk | Nature Genetics | 2017 | 426 |
| 26 | Genome-wide associations for birth weight and correlations with adult disease | Nature | 2016 | 406 |
| 27 | Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors | Nature Genetics | 2019 | 402 |
| 28 | Case–Control and Two-Gate Designs in Diagnostic Accuracy Studies | Clinical Chemistry | 2005 | 393 |
| 29 | Clopidogrel nonresponsiveness in patients undergoing percutaneous coronary intervention with stenting: A systematic review and meta-analysis | American Heart Journal | 2007 | 390 |
| 30 | Anti-inflammatory cytokine profile and mortality in febrile patients | Lancet, The | 1998 | 384 |
| 31 | Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study | Lancet Neurology, The | 2009 | 370 |
| 32 | Heart rate variability and first cardiovascular event in populations without known cardiovascular disease: meta-analysis and dose–response meta-regression | Europace | 2013 | 357 |
| 33 | Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes | Nature Genetics | 2018 | 356 |
| 34 | European Society of Clinical Microbiology and Infectious Diseases (ESCMID): Data review and recommendations for diagnosing Clostridium difficile-infection (CDI) | Clinical Microbiology and Infection | 2009 | 353 |
| 35 | The power of genetic diversity in genome-wide association studies of lipids | Nature | 2021 | 353 |
| 36 | The trans-ancestral genomic architecture of glycemic traits | Nature Genetics | 2021 | 341 |
| 37 | Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a contemporary view of the published literature | European Respiratory Journal | 2017 | 339 |
| 38 | Association between weight or body mass index and hand osteoarthritis: a systematic review | Annals of the Rheumatic Diseases | 2010 | 332 |
| 39 | Multisystem Morbidity and Mortality in Cushing's Syndrome: A Cohort Study | Journal of Clinical Endocrinology and Metabolism | 2013 | 324 |
| 40 | Observational Research, Randomised Trials, and Two Views of Medical Science | PLoS Medicine | 2008 | 317 |
| 41 | Venous thrombosis risk associated with plasma hypofibrinolysis is explained by elevated plasma levels of TAFI and PAI-1 | Blood | 2010 | 309 |
| 42 | External validation of prognostic models: what, why, how, when and where? | CKJ: Clinical Kidney Journal | 2021 | 306 |
| 43 | F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis | Blood | 2012 | 305 |
| 44 | Sample size calculations: basic principles and common pitfalls | Nephrology Dialysis Transplantation | 2010 | 302 |
| 45 | A Reduced Sensitivity for Activated Protein C in the Absence of Factor V Leiden Increases the Risk of Venous Thrombosis | Blood | 1999 | 299 |
| 46 | PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study | Lancet Diabetes and Endocrinology,the | 2017 | 298 |
| 47 | Different combined oral contraceptives and the risk of venous thrombosis: systematic review and network meta-analysis | BMJ, The | 2013 | 294 |
| 48 | Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity | Nature Genetics | 2018 | 286 |
| 49 | Genome-wide analysis identifies 12 loci influencing human reproductive behavior | Nature Genetics | 2016 | 284 |
| 50 | COSMOS-E: Guidance on conducting systematic reviews and meta-analyses of observational studies of etiology | PLoS Medicine | 2019 | 284 |
