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Department of Clinical Pharmacy and Toxicology
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top-articles
Department of Clinical Pharmacy and Toxicology
519
(top 1%)
papers
19.2K
(top 1%)
citations
64
(top 1%)
h
-index
120
(top 1%)
g
-index
550
all documents
20.8K
doc citations
3.3K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Genetics of rheumatoid arthritis contributes to biology and drug discovery
Nature
2014
1,974
2
Pharmacogenetics: From Bench to Byte— An Update of Guidelines
Clinical Pharmacology and Therapeutics
2011
869
3
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for
CYP3A5
Genotype and Tacrolimus Dosing
Clinical Pharmacology and Therapeutics
2015
491
4
Clinical pharmacogenetics implementation consortium guideline (CPIC) for
CYP2D6
and
CYP2C19
genotypes and dosing of tricyclic antidepressants: 2016 update
Clinical Pharmacology and Therapeutics
2017
450
5
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 Update
Clinical Pharmacology and Therapeutics
2018
407
6
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants
Clinical Pharmacology and Therapeutics
2013
397
7
Standardizing
CYP
2D6
Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group
Clinical and Translational Science
2020
353
8
Arsenic neurotoxicity — A review
Human and Experimental Toxicology
2007
331
9
Cardiotoxicity of cytotoxic drugs
Cancer Treatment Reviews
2004
318
10
Clinical Pharmacogenetics Implementation Consortium Guidelines for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing
Clinical Pharmacology and Therapeutics
2013
298
11
Recent insights in the pharmacological actions of methotrexate in the treatment of rheumatoid arthritis
Rheumatology
2007
274
12
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for
CYP2D6
and Tamoxifen Therapy
Clinical Pharmacology and Therapeutics
2018
244
13
Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium
Clinical Pharmacology and Therapeutics
2017
240
14
DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis
Lancet Oncology, The
2018
238
15
CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses
Biomaterials
2015
235
16
Pharmacogenetics: From Bench to Byte
Clinical Pharmacology and Therapeutics
2008
229
17
Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors
Clinical Pharmacokinetics
2019
222
18
Pharmacokinetics/Pharmacodynamics of Bisphosphonates
Clinical Pharmacokinetics
2005
198
19
Comparison of the Guidelines of the Clinical Pharmacogenetics Implementation Consortium and the Dutch Pharmacogenetics Working Group
Clinical Pharmacology and Therapeutics
2018
186
20
Translating Pharmacogenomics: Challenges on the Road to the Clinic
PLoS Medicine
2007
174
21
Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease
Gastroenterology
2015
169
22
HPV16 synthetic long peptide (HPV16-SLP) vaccination therapy of patients with advanced or recurrent HPV16-induced gynecological carcinoma, a phase II trial
Journal of Translational Medicine
2013
165
23
Pharmacology of oxaliplatin and the use of pharmacogenomics to individualize therapy
Cancer Treatment Reviews
2005
161
24
Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T‐cell activation
European Journal of Immunology
2013
157
25
Development of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application
Peptides
2006
155
26
Effect of Concomitant CYP2D6 Inhibitor Use and Tamoxifen Adherence on Breast Cancer Recurrence in Early-Stage Breast Cancer
Journal of Clinical Oncology
2010
150
27
Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis
PLoS Genetics
2013
146
28
Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response
Clinical Cancer Research
2016
132
29
Immunization with a P53 synthetic long peptide vaccine induces P53‐specific immune responses in ovarian cancer patients, a phase II trial
International Journal of Cancer
2009
123
30
Explaining Variability in Tacrolimus Pharmacokinetics to Optimize Early Exposure in Adult Kidney Transplant Recipients
Therapeutic Drug Monitoring
2009
119
31
Exhaled Nitric Oxide (NO) Is Reduced Shortly after Bronchoconstriction to Direct and Indirect Stimuli in Asthma
American Journal of Respiratory and Critical Care Medicine
1998
118
32
Effect of Milk Thistle (Silybum marianum) on the Pharmacokinetics of Irinotecan
Clinical Cancer Research
2005
115
33
Prospective DPYD genotyping to reduce the risk of fluoropyrimidine-induced severe toxicity: Ready for prime time
European Journal of Cancer
2016
110
34
Poly-(lactic-co-glycolic-acid)-based particulate vaccines: Particle uptake by dendritic cells is a key parameter for immune activation
Vaccine
2015
109
35
Influence of CYP3A4 Inhibition on the Steady-State Pharmacokinetics of Imatinib
Clinical Cancer Research
2007
107
36
Hormonal and reproductive factors in relation to melanoma in women: Current review and meta-analysis
European Journal of Cancer
2011
106
37
Sirolimus and everolimus in kidney transplantation
Drug Discovery Today
2015
101
38
Genetic polymorphisms and paclitaxel- or docetaxel-induced toxicities: A systematic review
Cancer Treatment Reviews
2015
101
39
Mitotane has a strong and a durable inducing effect on CYP3A4 activity
European Journal of Endocrinology
2011
99
40
A controlled human Schistosoma mansoni infection model to advance novel drugs, vaccines and diagnostics
Nature Medicine
2020
97
41
Optimization of encapsulation of a synthetic long peptide in PLGA nanoparticles: Low-burst release is crucial for efficient CD8+ T cell activation
European Journal of Pharmaceutics and Biopharmaceutics
2013
95
42
SERIES: eHealth in primary care. Part 1: Concepts, conditions and challenges
European Journal of General Practice
2019
92
43
Activation of Tumor-Promoting Type 2 Macrophages by EGFR-Targeting Antibody Cetuximab
Clinical Cancer Research
2011
91
44
A Review of Mathematical Models for Tumor Dynamics and Treatment Resistance Evolution of Solid Tumors
CPT: Pharmacometrics and Systems Pharmacology
2019
90
45
Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology
Therapeutic Drug Monitoring
2021
89
46
Intrathecal baclofen for dystonia of complex regional pain syndrome
Pain
2009
88
47
Loading and maintenance dose algorithms for phenprocoumon and acenocoumarol using patient characteristics and pharmacogenetic data
European Heart Journal
2011
86
48
Concordance of Predictive Markers for EGFR Inhibitors in Primary Tumors and Metastases in Colorectal Cancer: A Review
Oncologist
2011
85
49
Characterizing the role of enterohepatic recycling in the interactions between mycophenolate mofetil and calcineurin inhibitors in renal transplant patients by pharmacokinetic modelling
British Journal of Clinical Pharmacology
2005
82
50
Clinical and pharmacogenetic factors associated with irinotecan toxicity
Cancer Treatment Reviews
2008
82
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