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Top Articles

#TitleJournalYearCitations
1Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
2Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
3Macrophage functional polarization (M1/M2) in response to varying fiber and pore dimensions of electrospun scaffoldsBiomaterials2013351
4Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and MetastasesCancer Cell2009332
5Sphingosine‐1‐phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respirationFASEB Journal2011307
6The TLR3 signaling complex forms by cooperative receptor dimerizationProceedings of the National Academy of Sciences of the United States of America2008255
7Mitochondrial-targeted Signal Transducer and Activator of Transcription 3 (STAT3) Protects against Ischemia-induced Changes in the Electron Transport Chain and the Generation of Reactive Oxygen SpeciesJournal of Biological Chemistry2011188
8The Import of the Transcription Factor STAT3 into Mitochondria Depends on GRIM-19, a Component of the Electron Transport ChainJournal of Biological Chemistry2013181
9The Immunomodulator FTY720 Has a Direct Cytoprotective Effect in Oligodendrocyte ProgenitorsJournal of Pharmacology and Experimental Therapeutics2007175
10Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoidsNature2013159
11Tie1-Tie2 Interactions Mediate Functional Differences between Angiopoietin LigandsMolecular Cell2010151
12Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expressionHepatology2015151
13The Role of Vascular Endothelial Growth Factor in Pulmonary Arterial Hypertension. The Angiogenesis ParadoxAmerican Journal of Respiratory Cell and Molecular Biology2014142
14Opioid addiction and pregnancy: Perinatal exposure to buprenorphine affects myelination in the developing brainGlia2008112
15Over‐expression of secreted proteins from mammalian cell linesProtein Science2014110
16HDAC inhibitors enhance the immunotherapy response of melanoma cellsOncotarget2017108
17Cytoprotection by the modulation of mitochondrial electron transport chain: The emerging role of mitochondrial STAT3Mitochondrion2012104
18Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic painJournal of Experimental Medicine2018102
19mda-7/IL-24: A unique member of the IL-10 gene family promoting cancer-targeted toxicityCytokine and Growth Factor Reviews201095
20Inhibition of MCL-1 enhances Lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagyCancer Biology and Therapy200988
21Gβ5 Is Required for Normal Light Responses and Morphology of Retinal ON-Bipolar CellsJournal of Neuroscience200785
22Interleukin-1 Regulates the Expression of Sphingosine Kinase 1 in Glioblastoma CellsJournal of Biological Chemistry200982
23BCL-2 Family Inhibitors Enhance Histone Deacetylase Inhibitor and Sorafenib Lethality via Autophagy and Overcome Blockade of the Extrinsic Pathway to Facilitate KillingMolecular Pharmacology200982
24Sorafenib and Vorinostat Kill Colon Cancer Cells by CD95-Dependent and -Independent MechanismsMolecular Pharmacology200981
25GRP78/BiP/HSPA5/Dna K is a universal therapeutic target for human diseaseJournal of Cellular Physiology201579
26The Geometry of Locomotive Behavioral States in C. elegansPLoS ONE201379
27ASI Regulates Satiety Quiescence in C. elegansJournal of Neuroscience201375
28FTY720 Reduces Inflammation and Promotes Functional Recovery after Spinal Cord InjuryJournal of Neurotrauma200967
29Eradication of Therapy-resistant Human Prostate Tumors Using an Ultrasound-guided Site-specific Cancer Terminator Virus Delivery ApproachMolecular Therapy201067
30Biological Characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a Selective Sphingosine Kinase-2 Inhibitor and Anticancer AgentPLoS ONE201367
31Background Light Produces a Recoverin-Dependent Modulation of Activated-Rhodopsin Lifetime in Mouse RodsJournal of Neuroscience201066
32hnRNP U Enhances Caspase-9 Splicing and Is Modulated by AKT-dependent Phosphorylation of hnRNP LJournal of Biological Chemistry201365
33High‐throughput miRNA sequencing and identification of biomarkers for forensically relevant biological fluidsElectrophoresis201665
34A Complex of Nuclear Factor I-X3 and STAT3 Regulates Astrocyte and Glioma Migration through the Secreted Glycoprotein YKL-40Journal of Biological Chemistry201164
35Modulation of Mouse Rod Response Decay by Rhodopsin Kinase and RecoverinJournal of Neuroscience201260
36Ceramide Kinase Regulates the Production of Tumor Necrosis Factor α (TNFα) via Inhibition of TNFα-converting EnzymeJournal of Biological Chemistry201159
37Orm/ORMDL proteins: Gate guardians and master regulatorsAdvances in Biological Regulation201858
38Controlling Mast Cell Activation and Homeostasis: Work Influenced by Bill Paul That Continues TodayFrontiers in Immunology201857
39HDAC inhibitors enhance neratinib activity and when combined enhance the actions of an anti-PD-1 immunomodulatory antibody in vivoOncotarget201757
40The Role of Ceramide-1-Phosphate in Biological FunctionsHandbook of Experimental Pharmacology201356
41Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase AxlGenes and Cancer201255
42Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degenerationProceedings of the National Academy of Sciences of the United States of America201355
43Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammationPain201755
44Ceramide plays a prominent role in MDA‐7/IL‐24‐induced cancer‐specific apoptosisJournal of Cellular Physiology201054
45PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cellsAutophagy200853
46Adaptation of Porphyromonas gingivalis to microaerophilic conditions involves increased consumption of formate and reduced utilization of lactateMicrobiology (United Kingdom)200953
47A Panel of MicroRNAs as Diagnostic Biomarkers for the Identification of Prostate CancerInternational Journal of Molecular Sciences201753
48Extracellular and intracellular sphingosine-1-phosphate in cancerCancer and Metastasis Reviews201152
49Epidermal growth factor induces matrix metalloproteinase-1 (MMP-1) expression and invasion in glioma cell lines via the MAPK pathwayJournal of Neuro-Oncology201152
50Structural basis for angiopoietin-1–mediated signaling initiationProceedings of the National Academy of Sciences of the United States of America201352