| # | Title | Journal | Year | Citations |
|---|
| 1 | The 16-Item quick inventory of depressive symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression | Biological Psychiatry | 2003 | 2,981 |
| 2 | Genetic Epidemiology of Major Depression: Review and Meta-Analysis | American Journal of Psychiatry | 2000 | 2,683 |
| 3 | Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression | Nature Genetics | 2018 | 2,224 |
| 4 | Causal Relationship Between Stressful Life Events and the Onset of Major Depression | American Journal of Psychiatry | 1999 | 2,034 |
| 5 | The Structure of Genetic and Environmental Risk Factors for Common Psychiatric and Substance Use Disorders in Men and Women | Archives of General Psychiatry | 2003 | 1,640 |
| 6 | Genome-wide association analysis identifies 13 new risk loci for schizophrenia | Nature Genetics | 2013 | 1,395 |
| 7 | Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use | Nature Genetics | 2019 | 1,307 |
| 8 | The Adolescent Brain Cognitive Development (ABCD) study: Imaging acquisition across 21 sites | Developmental Cognitive Neuroscience | 2018 | 1,282 |
| 9 | Childhood Sexual Abuse and Adult Psychiatric and Substance Use Disorders in Women | Archives of General Psychiatry | 2000 | 1,098 |
| 10 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 11 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 12 | Stressful life events, genetic liability, and onset of an episode of major depression in women | American Journal of Psychiatry | 1995 | 901 |
| 13 | Examining the association between parenting and childhood anxiety: A meta-analysis | Clinical Psychology Review | 2007 | 877 |
| 14 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects | Nature Genetics | 2017 | 838 |
| 15 | Genetic Variation in the 6p22.3 Gene DTNBP1, the Human Ortholog of the Mouse Dysbindin Gene, Is Associated with Schizophrenia | American Journal of Human Genetics | 2002 | 786 |
| 16 | Smoking and Major Depression | Archives of General Psychiatry | 1993 | 755 |
| 17 | Major Depression and Generalized Anxiety Disorder | Archives of General Psychiatry | 1992 | 688 |
| 18 | Analysis of polygenic risk score usage and performance in diverse human populations | Nature Communications | 2019 | 656 |
| 19 | The Structure of the Genetic and Environmental Risk Factors for Six Major Psychiatric Disorders in Women | Archives of General Psychiatry | 1995 | 631 |
| 20 | Gender Differences in Treatment Response to Sertraline Versus Imipramine in Chronic Depression | American Journal of Psychiatry | 2000 | 611 |
| 21 | The Roscommon Family Study | Archives of General Psychiatry | 1993 | 603 |
| 22 | Lifetime Prevalence, Demographic Risk Factors, and Diagnostic Validity of Nonaffective Psychosis as Assessed in a US Community Sample | Archives of General Psychiatry | 1996 | 601 |
| 23 | The Genetics of Major Depression | Neuron | 2014 | 559 |
| 24 | A Longitudinal Twin Study of Personality and Major Depression in Women | Archives of General Psychiatry | 1993 | 558 |
| 25 | Personality and Major Depression | Archives of General Psychiatry | 2006 | 554 |
| 26 | Specifying race-ethnic differences in risk for psychiatric disorder in a USA national sample | Psychological Medicine | 2006 | 542 |
| 27 | Lifetime risk and persistence of psychiatric disorders across ethnic groups in the United States | Psychological Medicine | 2005 | 526 |
| 28 | Examining the association between parenting and childhood depression: A meta-analysis | Clinical Psychology Review | 2007 | 516 |
| 29 | A Population-Based Twin Study of the Relationship Between Neuroticism and Internalizing Disorders | American Journal of Psychiatry | 2006 | 508 |
| 30 | Critical slowing down as early warning for the onset and termination of depression | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 504 |
| 31 | Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders | Nature Neuroscience | 2018 | 490 |
| 32 | The prediction of major depression in women: toward an integrated etiologic model | American Journal of Psychiatry | 1993 | 489 |
| 33 | Major Depressive Disorder | Neuron | 2000 | 486 |
| 34 | The Genetic Epidemiology of Phobias in Women | Archives of General Psychiatry | 1992 | 474 |
| 35 | Illicit Psychoactive Substance Use, Heavy Use, Abuse, and Dependence in a US Population-Based Sample of Male Twins | Archives of General Psychiatry | 2000 | 455 |
| 36 | A potential vulnerability locus for schizophrenia on chromosome 6p24–22: evidence for genetic heterogeneity | Nature Genetics | 1995 | 448 |
| 37 | Toward a Philosophical Structure for Psychiatry | American Journal of Psychiatry | 2005 | 433 |
| 38 | Gender Differences in the Rates of Exposure to Stressful Life Events and Sensitivity to Their Depressogenic Effects | American Journal of Psychiatry | 2001 | 429 |
| 39 | Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations | Cell | 2019 | 428 |
| 40 | Genetic Risk, Number of Previous Depressive Episodes, and Stressful Life Events in Predicting Onset of Major Depression | American Journal of Psychiatry | 2001 | 426 |
| 41 | A Population-Based Twin Study of Major Depression in Women | Archives of General Psychiatry | 1992 | 420 |
| 42 | Genetic and Environmental Influences on Alcohol, Caffeine, Cannabis, and Nicotine Use From Early Adolescence to Middle Adulthood | Archives of General Psychiatry | 2008 | 412 |
| 43 | Sex Differences in the Relationship Between Social Support and Risk for Major Depression: A Longitudinal Study of Opposite-Sex Twin Pairs | American Journal of Psychiatry | 2005 | 391 |
| 44 | Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multisite, randomised, sham-controlled trial | Lancet Psychiatry,the | 2017 | 382 |
| 45 | A test of the equal-environment assumption in twin studies of psychiatric illness | Behavior Genetics | 1993 | 376 |
| 46 | Co-morbid major depression and generalized anxiety disorders in the National Comorbidity Survey follow-up | Psychological Medicine | 2008 | 374 |
| 47 | Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability | Molecular Psychiatry | 2018 | 374 |
| 48 | Meta-analysis of genome-wide association studies of anxiety disorders | Molecular Psychiatry | 2016 | 373 |
| 49 | Childhood Parental Loss and Adult Psychopathology in Women | Archives of General Psychiatry | 1992 | 360 |
| 50 | Personality and comorbidity of common psychiatric disorders | British Journal of Psychiatry | 2005 | 358 |
