| # | Title | Journal | Year | Citations |
|---|
| 1 | ESMO Consensus Guidelines for management of patients with colon and rectal cancer. A personalized approach to clinical decision making | Annals of Oncology | 2012 | 1,233 |
| 2 | Prognostic Value of Mature MicroRNA-21 and MicroRNA-205 Overexpression in Non–Small Cell Lung Cancer by Quantitative Real-Time RT-PCR | Clinical Chemistry | 2008 | 415 |
| 3 | Prospective evaluation of effects of broad-spectrum antibiotics on gastrointestinal yeast colonization of humans | Antimicrobial Agents and Chemotherapy | 1993 | 153 |
| 4 | Six versus 12 months of adjuvant trastuzumab in combination with dose-dense chemotherapy for women with HER2-positive breast cancer: a multicenter randomized study by the Hellenic Oncology Research Group (HORG) | Annals of Oncology | 2015 | 153 |
| 5 | A multicenter randomized clinical trial comparing paclitaxel–cisplatin–etoposide versus cisplatin–etoposide as first-line treatment in patients with small-cell lung cancer | Annals of Oncology | 2001 | 139 |
| 6 | Comparison of the pharmacokinetics of 68Ga-DOTATOC and [18F]FDG in patients with metastatic neuroendocrine tumours scheduled for 90Y-DOTATOC therapy | European Journal of Nuclear Medicine and Molecular Imaging | 2006 | 134 |
| 7 | Trastuzumab decreases the incidence of clinical relapses in patients with early breast cancer presenting chemotherapy-resistant CK-19mRNA-positive circulating tumor cells: results of a randomized phase II study | Annals of Oncology | 2012 | 133 |
| 8 | Evaluation of the pharmacokinetics of 68Ga-DOTATOC in patients with metastatic neuroendocrine tumours scheduled for 90Y-DOTATOC therapy | European Journal of Nuclear Medicine and Molecular Imaging | 2006 | 115 |
| 9 | Front-Line Treatment of Advanced Non–Small-Cell Lung Cancer With Docetaxel and Gemcitabine: A Multicenter Phase II Trial | Journal of Clinical Oncology | 1999 | 114 |
| 10 | Pemetrexed versus erlotinib in pretreated patients with advanced non–small cell lung cancer: A Hellenic Oncology Research Group (HORG) randomized phase 3 study | Cancer | 2013 | 106 |
| 11 | Gene expression profile of circulating tumor cells in breast cancer by RT-qPCR | BMC Cancer | 2011 | 97 |
| 12 | The promise of immunotherapy in head and neck squamous cell carcinoma | Annals of Oncology | 2016 | 95 |
| 13 | Treatment of Pancreatic Cancer With Docetaxel and Granulocyte Colony-Stimulating Factor: A Multicenter Phase II Study | Journal of Clinical Oncology | 1999 | 79 |
| 14 | Detection of Mammaglobin A-mRNA-positive circulating tumor cells in peripheral blood of patients with operable breast cancer with nested RT-PCR | Clinical Biochemistry | 2006 | 79 |
| 15 | Breast cancer metastasis suppressor-1 promoter methylation in cell-free DNA provides prognostic information in non-small cell lung cancer | British Journal of Cancer | 2014 | 68 |
| 16 | SOX17 promoter methylation in plasma circulating tumor DNA of patients with non-small cell lung cancer | Clinical Chemistry and Laboratory Medicine | 2016 | 66 |
| 17 | First-line treatment of advanced non-small-cell lung cancer with docetaxel and cisplatin: A multicenter phase II study | Annals of Oncology | 1998 | 64 |
| 18 | Quantitative assessment of SSTR2 expression in patients with non-small cell lung cancer using68Ga-DOTATOC PET and comparison with18F-FDG PET | European Journal of Nuclear Medicine and Molecular Imaging | 2006 | 64 |
| 19 | Evaluation of PD-L1/PD-1 on circulating tumor cells in patients with advanced non-small cell lung cancer | Therapeutic Advances in Medical Oncology | 2018 | 61 |
| 20 | Short-Term Exposure of Cancer Cells to Micromolar Doses of Paclitaxel, with or without Hyperthermia, Induces Long-Term Inhibition of Cell Proliferation and Cell Death In Vitro | Annals of Surgical Oncology | 2007 | 57 |
| 21 | Successful Conservative Treatment of Neutropenic Enterocolitis Complicating Taxane-Based Chemotherapy | American Journal of Clinical Oncology: Cancer Clinical Trials | 2000 | 55 |
| 22 | Docetaxel-induced lymphopenia in patients with solid tumors | Cancer | 2000 | 52 |
| 23 | First-line treatment of advanced nonsmall cell lung carcinoma with docetaxel and vinorelbine | Cancer | 1998 | 51 |
| 24 | Circulating cancer cells | Annals of Oncology | 2010 | 48 |
| 25 | Treatment of Non-Small-Cell Lung Cancer With Prolonged Oral Etoposide | American Journal of Clinical Oncology: Cancer Clinical Trials | 1998 | 44 |
| 26 | Fungal infections in cancer patients: an escalating problem | In Vivo | 1992 | 44 |
| 27 | Effects of broad-spectrum antibiotics on colonization of gastrointestinal tracts of mice by Candida albicans | Antimicrobial Agents and Chemotherapy | 1994 | 43 |
| 28 | International study on inter-reader variability for circulating tumor cells in breast cancer | Breast Cancer Research | 2014 | 43 |
| 29 | Salvage treatment with paclitaxel and gemcitabine for patients with non-small-cell lung cancer after cisplatin- or docetaxel-based chemotherapy: A multicenter phase II study | Annals of Oncology | 1998 | 42 |
| 30 | The hard road to data interpretation: 3 or 6 months of adjuvant chemotherapy for patients with stage III colon cancer? | Annals of Oncology | 2018 | 29 |
| 31 | Assessment of highly angiogenic and disseminated in the peripheral blood disease in breast cancer patients predicts for resistance to adjuvant chemotherapy and early relapse | International Journal of Cancer | 2004 | 28 |
| 32 | Application of data mining techniques and data analysis methods to measure cancer morbidity and mortality data in a regional cancer registry: The case of the island of Crete, Greece | Computer Methods and Programs in Biomedicine | 2017 | 28 |
| 33 | A new prognostic and predictive tool for shared decision making in stage III colon cancer | European Journal of Cancer | 2020 | 27 |
| 34 | Carboplatin, Methotrexate and 5-Fluorouracil in Combination with Medroxyprogesterone Acetate (JMF-M) in the Treatment of Advanced or Recurrent Endometrial Carcinoma: A Hellenic Cooperative Oncology Group Study | Oncology | 1999 | 25 |
| 35 | FCGR polymorphisms and cetuximab efficacy in chemorefractory metastatic colorectal cancer: an international consortium study | Gut | 2015 | 22 |
| 36 | Salvage Chemotherapy With Paclitaxel, Vinorelbine, and Cisplatin (PVC) in Anthracycline-Resistant Advanced Breast Cancer | American Journal of Clinical Oncology: Cancer Clinical Trials | 1998 | 22 |
| 37 | Immunotherapy in Metastatic Colorectal Cancer: Could the Latest Developments Hold the Key to Improving Patient Survival? | Cancers | 2020 | 20 |
| 38 | Prognostic Significance of the Detection of Peripheral Blood CEACAM5mRNA-Positive Cells by Real-Time Polymerase Chain Reaction in Operable Colorectal Cancer | Clinical Cancer Research | 2011 | 19 |
| 39 | Dose-Escalation Study of Docetaxel in Combination With Mitoxantrone as First-Line Treatment in Patients With Metastatic Breast Cancer | Journal of Clinical Oncology | 1999 | 18 |
| 40 | Docetaxel (Taxotere) in the Treatment of Non-Small Cell Lung Cancer | Current Medicinal Chemistry | 2002 | 18 |
| 41 | Cisplatin–etoposide alternating with topotecan in patients with extensive stage small cell lung cancer (SCLC) | Lung Cancer | 2002 | 18 |
| 42 | MKAD-21 Suppresses the Oncogenic Activity of the miR-21/PPP2R2A/ERK Molecular Network in Bladder Cancer | Molecular Cancer Therapeutics | 2018 | 17 |
| 43 | Immunohistochemical Study of the Angiogenetic Network of VEGF, HIF1α, VEGFR-2 and Endothelial Nitric Oxide Synthase (eNOS) in Human Breast Cancer | Pathology and Oncology Research | 2012 | 16 |
| 44 | Sequential Versus Alternating Administration of Cisplatin/Etoposide and Topotecan as First-Line Treatment in Extensive-Stage Small-Cell Lung Cancer: Preliminary Results of a Phase III Trial of the Hellenic Oncology Research Group | Clinical Lung Cancer | 2005 | 14 |
| 45 | Sequential administration of cisplatin–etoposide followed by topotecan in patients with extensive stage small cell lung cancer. A multicenter phase II study | Lung Cancer | 2003 | 13 |
| 46 | Autocrine IL-2-dependent growth of a newly established CD3+, CD16−, CD56+, CD57+, JH−, TCRβ−, TCRγ− leukemia cell line (NOI-90) | Leukemia | 1997 | 12 |
| 47 | Immunohistochemical study of pElk-1 expression in human breast cancer: Association with breast cancer biologic profile and clinicopathologic features | Breast | 2013 | 12 |
| 48 | Prospective Randomized Study of Aminoglutethimide (AG) versus Medroxyprogesterone Acetate (MPA) versus AG+MPA in Generalized Breast Cancer | Oncology | 1994 | 11 |
| 49 | Development and validation of a multiplex methylation specific PCR-coupled liquid bead array for liquid biopsy analysis | Clinica Chimica Acta | 2016 | 10 |
| 50 | Serum IGF-1, IGFBP-3 levels and circulating tumor cells (CTCs) in early breast cancer patients | Growth Hormone and IGF Research | 2017 | 10 |
