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Top Articles

#TitleJournalYearCitations
1TFOS DEWS II Epidemiology ReportOcular Surface20171,490
2Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of ObesityJournal of Neuroscience2009886
3TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and MonkeysCell Metabolism2013340
4Peginterferon alfa-2b and Ribavirin: Effective in Patients With Hepatitis C Who Failed Interferon alfa/Ribavirin TherapyGastroenterology2009225
5Inflammatory effects of snake venom myotoxic phospholipases A2Toxicon2003210
6Sustained efficacy, immunogenicity, and safety of the HPV-16/18 AS04-adjuvanted vaccineHuman Vaccines and Immunotherapeutics2014207
7Ischemia/Reperfusion Injury Revisited: An Overview of the Latest Pharmacological StrategiesInternational Journal of Molecular Sciences2019187
8Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucomaNature Genetics2016147
9Development and Function of the Blood-Brain Barrier in the Context of Metabolic ControlFrontiers in Neuroscience2017145
10Diabetic Retinal Neurodegeneration Is Associated With Mitochondrial Oxidative Stress and Is Improved by an Angiotensin Receptor Blocker in a Model Combining Hypertension and DiabetesDiabetes2009123
11Long-Term Follow-Up of the First in Human Intravascular Delivery of AAV for Gene Transfer: AAV2-hFIX16 for Severe Hemophilia BMolecular Therapy2020123
12Effects of different protocol doses of low power gallium–aluminum–arsenate (Ga–Al–As) laser radiation (650 nm) on carrageenan induced rat paw ooedemaJournal of Photochemistry and Photobiology B: Biology2004122
13Sensitivity of Patient Outcomes to Pharmacist Interventions. Part III: Systematic Review and Meta-Analysis in Hyperlipidemia ManagementAnnals of Pharmacotherapy2008117
14Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in MiceJournal of Neuroscience2016116
15Recessive and Dominant De Novo ITPR1 Mutations Cause Gillespie SyndromeAmerican Journal of Human Genetics2016113
16Influence of Gut Microbiota on Subclinical Inflammation and Insulin ResistanceMediators of Inflammation2013111
17Pregnancies associated with sperm concentrations below 10 million/ml in clinical studies of a potential male contraceptive method, monthly depot medroxyprogesterone acetate and testosterone estersContraception1979102
18Acute inhibition of nitric oxide synthesis induces anxiolysis in the plus maze testEuropean Journal of Pharmacology1997101
19Relevant Aspects of Centrifugation Step in the Preparation of Platelet-Rich PlasmaISRN Hematology2014101
20Nosocomial infections in renal transplant patients: risk factors and treatment implications associated with urinary tract and surgical site infectionsJournal of Hospital Infection200699
21A Comparative Study on the Effect of Nicotine Administration and Cigarette Smoke Inhalation on Bone Healing Around Titanium ImplantsJournal of Periodontology200398
22A comparative study of severe scorpion envenomation in children caused by Tityus bahiensis and Tityus serrulatusRevista Do Instituto De Medicina Tropical De Sao Paulo199596
23Mast cell degranulation induced by two phospholipase A2 homologues: Dissociation between enzymatic and biological activitiesEuropean Journal of Pharmacology199893
24Epilepsy stigma: What do we know and where next?Epilepsy and Behavior201183
25Identification of CANT1 Mutations in Desbuquois DysplasiaAmerican Journal of Human Genetics200981
26Bariatric Surgery Does not Interfere With Sperm Quality—A Preliminary Long-Term StudyReproductive Sciences201278
27Comparison of Diagnostic Tests in Distinct Well-Defined Conditions Related to Dry Eye DiseasePLoS ONE201477
28Chronic nitric oxide inhibition as a model of hypertensive heart muscle diseaseBasic Research in Cardiology199676
29A 3-year multicentre randomized controlled trial of etonogestrel- and levonorgestrel-releasing contraceptive implants, with non-randomized matched copper-intrauterine device controlsHuman Reproduction201576
30Ovarian endocrine function through five years of continuous treatment with NORPLANT® subdermal contraceptive implantsContraception199073
31Efficacy of the HPV-16/18 AS04-Adjuvanted Vaccine Against Low-Risk HPV Types (PATRICIA Randomized Trial): An Unexpected ObservationJournal of Infectious Diseases201373
32Extended use up to 5 years of the etonogestrel-releasing subdermal contraceptive implant: comparison to levonorgestrel-releasing subdermal implantHuman Reproduction201673
33Dilatation of the urinary tract during pregnancy: Proposal of a curve of maximal caliceal diameter by gestational ageAmerican Journal of Obstetrics and Gynecology199872
34Multicenter Study Using Desorption-Electrospray-Ionization-Mass-Spectrometry Imaging for Breast-Cancer DiagnosisAnalytical Chemistry201870
35Gait analysis comparing Parkinson's disease with healthy elderly subjectsArquivos De Neuro-Psiquiatria201069
36Differentiated thyroid carcinomas may elude the immune system by B7H1 upregulationEndocrine-Related Cancer201369
37Fractal dimension of chromatin is an independent prognostic factor for survival in melanomaBMC Cancer201068
38Simultaneous determination of nitrite and nitrate anions in plasma, urine and cell culture supernatants by high-performance liquid chromatography with post-column reactionsBiomedical Applications199667
39Hippocampal gene expression dysregulation of Klotho, nuclear factor kappa B and tumor necrosis factor in temporal lobe epilepsy patientsJournal of Neuroinflammation201367
40Effect of crotapotin and heparin on the rat paw oedema induced by different secretory phospholipases A2Toxicon200066
41Exercise training improves relaxation response and SOD-1 expression in aortic and mesenteric rings from high caloric diet-fed ratsBMC Physiology200864
42Good interobserver and intraobserver agreement in the evaluation of the new ILAE classification of focal cortical dysplasiasEpilepsia201263
43Risk factors for ulceration and amputation in diabetic foot: study in a cohort of 496 patientsEndocrine201362
44Bacterial Nanocellulose Loaded with Bromelain: Assessment of Antimicrobial, Antioxidant and Physical-Chemical PropertiesScientific Reports201761
45Freeze-dried jaboticaba peel powder improves insulin sensitivity in high-fat-fed miceBritish Journal of Nutrition201359
46Effect of Antiretroviral Therapy Including Lopinavir/Ritonavir or Efavirenz on Etonogestrel-Releasing Implant Pharmacokinetics in HIV-Positive WomenJournal of Acquired Immune Deficiency Syndromes (1999)201459
47Chemical Modifications on Polystyrene Latex: Preparation and Characterization for Use in Immunological ApplicationsPolymers for Advanced Technologies199758
48Control of endometriosis-associated pain with etonogestrel-releasing contraceptive implant and 52-mg levonorgestrel-releasing intrauterine system: randomized clinical trialFertility and Sterility201858
49Causes and consequences of coagulation activation in sepsis: an evolutionary medicine perspectiveBMC Medicine201556
50Diagnostic Accuracy of the Short Physical Performance Battery for Detecting Frailty in Older PeoplePhysical Therapy202056