# | Title | Journal | Year | Citations |
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1 | Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease | Nature | 2012 | 4,038 |
2 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
3 | A reference panel of 64,976 haplotypes for genotype imputation | Nature Genetics | 2016 | 2,421 |
4 | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci | Nature Genetics | 2010 | 2,284 |
5 | Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics | PLoS Genetics | 2014 | 2,012 |
6 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
7 | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations | Nature Genetics | 2015 | 1,965 |
8 | Environment dominates over host genetics in shaping human gut microbiota | Nature | 2018 | 1,958 |
9 | Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study | Lancet, The | 2012 | 1,937 |
10 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
11 | Population-level analysis of gut microbiome variation | Science | 2016 | 1,716 |
12 | Systematic identification of trans eQTLs as putative drivers of known disease associations | Nature Genetics | 2013 | 1,544 |
13 | mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity | Science | 2014 | 1,517 |
14 | Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity | Science | 2016 | 1,398 |
15 | Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity | Science | 2014 | 1,338 |
16 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
17 | The neuroactive potential of the human gut microbiota in quality of life and depression | Nature Microbiology | 2019 | 1,206 |
18 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
19 | Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 | Nature Genetics | 2011 | 1,201 |
20 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
21 | Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses | Nature Genetics | 2016 | 870 |
22 | BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity | Cell Host and Microbe | 2018 | 860 |
23 | Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases | Nature Genetics | 2019 | 854 |
24 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects | Nature Genetics | 2017 | 838 |
25 | Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity | Cell | 2016 | 806 |
26 | GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment | Science | 2013 | 750 |
27 | Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity | Nature | 2017 | 743 |
28 | DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis | American Journal of Human Genetics | 2016 | 717 |
29 | Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming | Cell | 2018 | 705 |
30 | Getting up to speed with transcription elongation by RNA polymerase II | Nature Reviews Molecular Cell Biology | 2015 | 692 |
31 | Large-scale association analyses identify host factors influencing human gut microbiome composition | Nature Genetics | 2021 | 676 |
32 | The effect of host genetics on the gut microbiome | Nature Genetics | 2016 | 672 |
33 | Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes | Nature Genetics | 2007 | 670 |
34 | Evidence Based Selection of Housekeeping Genes | PLoS ONE | 2007 | 617 |
35 | Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci | Nature Genetics | 2016 | 617 |
36 | Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease | Gut | 2018 | 590 |
37 | Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression | Nature Genetics | 2021 | 590 |
38 | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture | Nature Genetics | 2013 | 578 |
39 | The transcriptional landscape of age in human peripheral blood | Nature Communications | 2015 | 533 |
40 | Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine | Nature Genetics | 2016 | 520 |
41 | Metabolic Induction of Trained Immunity through the Mevalonate Pathway | Cell | 2018 | 485 |
42 | Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy | Journal of Allergy and Clinical Immunology | 2011 | 424 |
43 | Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database | Gut | 2017 | 411 |
44 | Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database | Nature Genetics | 2014 | 410 |
45 | Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database | Gut | 2018 | 410 |
46 | Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disability | Nature Neuroscience | 2016 | 407 |
47 | Disease variants alter transcription factor levels and methylation of their binding sites | Nature Genetics | 2017 | 390 |
48 | Genome-wide patterns and properties of de novo mutations in humans | Nature Genetics | 2015 | 384 |
49 | The MHC locus and genetic susceptibility to autoimmune and infectious diseases | Genome Biology | 2017 | 384 |
50 | A novel microglial subset plays a key role in myelinogenesis in developing brain | EMBO Journal | 2017 | 375 |