| # | Title | Journal | Year | Citations |
|---|
| 1 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 2 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 3 | Prevalence of Frailty in Community‐Dwelling Older Persons: A Systematic Review | Journal of the American Geriatrics Society | 2012 | 2,125 |
| 4 | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations | Nature Genetics | 2015 | 1,965 |
| 5 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 6 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 7 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 8 | The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis | British Journal of Cancer | 2011 | 1,045 |
| 9 | Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits | Nature Genetics | 2018 | 924 |
| 10 | Interventions for treating obesity in children | The Cochrane Library | 2009 | 882 |
| 11 | Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses | Nature Genetics | 2016 | 870 |
| 12 | Common variants associated with plasma triglycerides and risk for coronary artery disease | Nature Genetics | 2013 | 754 |
| 13 | GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment | Science | 2013 | 750 |
| 14 | Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways | Nature Genetics | 2012 | 746 |
| 15 | DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis | American Journal of Human Genetics | 2016 | 717 |
| 16 | Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index | Nature Genetics | 2015 | 709 |
| 17 | Social relationships and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies | Ageing Research Reviews | 2015 | 683 |
| 18 | Genome-wide association analyses identify 18 new loci associated with serum urate concentrations | Nature Genetics | 2013 | 675 |
| 19 | Dutch Tariff for the Five-Level Version of EQ-5D | Value in Health | 2016 | 652 |
| 20 | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture | Nature Genetics | 2013 | 578 |
| 21 | Faecal calprotectin for screening of patients with suspected inflammatory bowel disease: diagnostic meta-analysis | BMJ: British Medical Journal | 2010 | 554 |
| 22 | A catalog of genetic loci associated with kidney function from analyses of a million individuals | Nature Genetics | 2019 | 549 |
| 23 | Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche | Nature | 2014 | 548 |
| 24 | Worsening Renal Function and Prognosis in Heart Failure: Systematic Review and Meta-Analysis | Journal of Cardiac Failure | 2007 | 527 |
| 25 | Automating network meta‐analysis | Research Synthesis Methods | 2012 | 523 |
| 26 | Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma | Nature Genetics | 2011 | 501 |
| 27 | Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk | Nature Genetics | 2017 | 492 |
| 28 | The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies | BMC Endocrine Disorders | 2014 | 440 |
| 29 | Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk | Nature Genetics | 2017 | 426 |
| 30 | Lung cancer probability in patients with CT-detected pulmonary nodules: a prespecified analysis of data from the NELSON trial of low-dose CT screening | Lancet Oncology, The | 2014 | 424 |
| 31 | Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function | Nature Communications | 2016 | 412 |
| 32 | Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy | Journal of Allergy and Clinical Immunology | 2011 | 406 |
| 33 | Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure | Nature Genetics | 2011 | 403 |
| 34 | New gene functions in megakaryopoiesis and platelet formation | Nature | 2011 | 401 |
| 35 | Decreased cardiac output, venous congestion and the association with renal impairment in patients with cardiac dysfunction | European Journal of Heart Failure | 2007 | 393 |
| 36 | Automated generation of node‐splitting models for assessment of inconsistency in network meta‐analysis | Research Synthesis Methods | 2016 | 372 |
| 37 | Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits | PLoS Genetics | 2013 | 371 |
| 38 | Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function | Nature Genetics | 2011 | 367 |
| 39 | The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals | Nature Genetics | 2016 | 362 |
| 40 | Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair | Nature Genetics | 2015 | 357 |
| 41 | The power of genetic diversity in genome-wide association studies of lipids | Nature | 2021 | 353 |
| 42 | Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer | Cancer Immunology, Immunotherapy | 2009 | 347 |
| 43 | Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes | JAMA - Journal of the American Medical Association | 2019 | 344 |
| 44 | A Program of Methodological Research to Arrive at the New International EQ-5D-5L Valuation Protocol | Value in Health | 2014 | 341 |
| 45 | Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis | PLoS Medicine | 2017 | 341 |
| 46 | The trans-ancestral genomic architecture of glycemic traits | Nature Genetics | 2021 | 341 |
| 47 | The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study | PLoS Genetics | 2015 | 331 |
| 48 | Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta‐analysis of European, North American and Australian cohorts | BJOG: an International Journal of Obstetrics and Gynaecology | 2019 | 327 |
| 49 | Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders | American Journal of Human Genetics | 2018 | 326 |
| 50 | Seventy-five genetic loci influencing the human red blood cell | Nature | 2012 | 320 |
